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BPC-157 Anti-inflammatory, angiogenic NF-κB inhibition, VEGF upregulation 60% reduction in serum ALT, 40% reduction in steatosis score (Journal of Physiology Paris) Lyophilized at -20°C; reconstituted at 2–8°C, use within 14 days…
Thymalin Thymic immune modulation. Normalizes T-cell function, reduces IL-6 and TNF-alpha Chronic inflammation reduction, endothelial protection 10–20 mg subcutaneous 2–3x weekly Targets downstream inflammation. Doesn't address a…
Thymalin T-regulatory cell restoration; reduces mast cell hypersensitivity through immune recalibration 3–6 weeks for sustained effect 10mg SC twice weekly × 8 weeks Phase 2 clinical data in MCAS populations Best for systemic imm…
BPC-157 VEGF upregulation, angiogenesis, collagen type I deposition Rodent tendon models show 30–40% faster repair; no large human trials 250–500 mcg daily SubQ Best for soft tissue microtears in ligaments and fascia where angiog…
BPC-157 VEGF upregulation, angiogenesis promotion, fibroblast activation 250–500mcg daily subcutaneous VEGFR-2, nitric oxide synthase, collagen synthesis 8–12 weeks for measurable strength improvement First-line choice for chroni…
MOTS-c Mitochondrial biogenesis via AMPK activation Increased oxidative capacity and fatty acid metabolism 30% improvement in time to exhaustion (mouse model) 5–15mg SC 2–3×/week Well-tolerated in animal studies; human safety dat…
| Peptide | Primary Mechanism | Injury Type Target | Typical Dose Range | Administration Frequency | Evidence Strength | Professional Assessment ||—|—|—|—|—|—|| BPC-157 | VEGF-mediated angiogenesis, tendon-to-bone healing | Ligam…
Ipamorelin (GH Secretagogue) Ghrelin receptor agonist → endogenous GH pulse → IGF-1 → hormone-sensitive lipase activation Lipolysis, lean mass preservation, protein synthesis 200–300 mcg SC nightly pre-sleep Individuals with low-…
GLP-1 Agonists (semaglutide, tirzepatide) Appetite suppression via hypothalamic GLP-1 receptor activation + delayed gastric emptying Reduced caloric intake (20–30% deficit) STEP-1: 14.9% weight loss at 68 weeks; SURMOUNT-1: 20.9%…
Cerebrolysin BDNF-like neurotrophic signaling Synaptic plasticity, dendritic arborisation Improved cognitive flexibility, working memory retention 10–30 mL IV daily (clinical); 1–5 mg/kg subcutaneous (research) Strongest evidence…
BPC-157 Tight junction repair, VEGF upregulation, mucosal healing IBS-D (diarrhea-predominant) 250–500 mcg subcutaneous twice daily Bacteriostatic water, 2–8°C storage, use within 28 days First-line for barrier dysfunction. Addre…
Cerebrolysin BDNF/NGF receptor agonism via multi-peptide mixture Requires IV/IM. Does not passively cross BBB 2.5–5 mL IM (scaled by weight) 4–6 hours Intramuscular or intravenous Best for protocols requiring broad neurotrophic s…
Selank GABA-A receptor upregulation Panic disorder, acute episodic anxiety 600mcg–2.4mg/day intranasal or subcutaneous 10–14 days Multiple RCTs, moderate-quality evidence Semax BDNF elevation, neuroprotection GAD, chronic stress-…
Thymalin T-cell maturation, Treg restoration Immune dysregulation, T-cell exhaustion Clinical use in Russia/Eastern Europe; limited Western trials 10mg SubQ every 48 hours × 10 doses Strongest immunomodulatory data for post-infec…
Cortisone shots: Fast pain relief (days) Temporary (3-6 months) Can weaken tissue long-term Limited number allowed Don't heal underlying issue Slower onset (weeks) Longer-lasting results Strengthen tissue Can use repeatedly Addre…
BPC-157: Can inject near affected joint for potential local benefit. TB-500: Works systemically, inject anywhere. GHK-Cu: Systemic effects, standard subcutaneous injection.
HA injections (for knees): Medical procedure ($500-2,000) Lubricates joint temporarily 6-12 month duration Doesn't heal tissue Moderate evidence Self-administered ($200-600 for protocol) Promotes healing Long-lasting results Heal…
Different immune goals require different peptide selections. This comparison helps match peptides to specific situations. Peptide Primary Mechanism Best For Evidence Quality Administration Cost Level Thymosin Alpha-1 T cell enhan…
Surgery: For severe structural damage High success rates for appropriate cases Long recovery (6-12 months) Expensive ($10,000-50,000) Irreversible For mild-moderate issues Can help avoid surgery Accelerate post-surgical healing V…
This table compares key peptides for fibromyalgia across important factors: Peptide Primary Mechanism Main Symptom Target Dose Range Best For BPC-157 Anti-inflammatory, healing Pain, gut symptoms 250-500mcg 2x daily Broad symptom…