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Peptide Therapy GuideClear peptide education

Understand the source comparison

Best Peptides for Lyme Disease: Research Comparison

Thymalin T-cell maturation, Treg restoration Immune dysregulation, T-cell exhaustion Clinical use in Russia/Eastern Europe; limited Western trials 10mg SubQ every 48 hours × 10 doses Strongest immunomodulatory data for post-infectious immune collapse BPC-157 V

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • Thymalin
  • T-cell maturation, Treg restoration
  • Immune dysregulation, T-cell exhaustion
  • Clinical use in Russia/Eastern Europe; limited Western trials
  • 10mg SubQ every 48 hours × 10 doses
  • Strongest immunomodulatory data for post-infectious immune collapse
  • BPC-157
  • VEGF/FGF-2 modulation, mitochondrial repair
  • Tissue damage, neuroborreliosis, gut permeability
  • Extensive rodent data; human case reports
  • 250–500 mcg SubQ daily
  • Most versatile—addresses multiple Lyme sequelae simultaneously
  • KPV
  • NF-κB inhibition, local anti-inflammatory
  • Persistent cytokine elevation, gut inflammation
  • Phase 2 ulcerative colitis trials ongoing
  • 500 mcg oral or 200 mcg SubQ daily
  • Best for gut-dominant symptoms and systemic inflammation
  • Cerebrolysin
  • Neurotrophic factor delivery, BDNF/NGF signaling
  • Cognitive dysfunction, neuroprotection
  • Approved in EU/Asia; 200+ clinical trials in stroke/dementia
  • 5–10 mL IV daily × 20 sessions
  • Gold standard for neuroborreliosis-associated cognitive decline
  • Dihexa
  • HGF receptor activation, synaptogenesis
  • Memory deficits, synaptic loss
  • Preclinical only; potent in animal models
  • 1–5 mg/kg in rodent studies (human dosing undefined)
  • Promising but early-stage; wait for human safety data
  • MK-677
  • GH/IGF-1 secretagogue
  • Anabolic recovery, immune cell proliferation
  • Human trials in sarcopenia/aging; well-tolerated
  • 25 mg oral daily
  • Useful adjunct for overall recovery acceleration, not Lyme-specific