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Peptide Therapy GuideClear peptide education

Understand the source comparison

Peptide Recomposition Protocol Comparison

GHRH Monotherapy CJC-1295 (no DAC) + Ipamorelin 1–2x daily (pre-bed, pre-workout) 2–4× baseline during pulses Minimal High. Preserves insulin sensitivity, supports fat loss phases Ghrelin Agonist Monotherapy MK-677 (ibutamoren) Once daily (evening preferred) 1

No winner is assigned.

This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • GHRH Monotherapy
  • CJC-1295 (no DAC) + Ipamorelin
  • 1–2x daily (pre-bed, pre-workout)
  • 2–4× baseline during pulses
  • Minimal
  • High. Preserves insulin sensitivity, supports fat loss phases
  • Ghrelin Agonist Monotherapy
  • MK-677 (ibutamoren)
  • Once daily (evening preferred)
  • 1.5–2× baseline sustained
  • Significant increase
  • Moderate. Appetite makes deficit adherence harder
  • Synergistic Stack
  • CJC-1295 + Ipamorelin + low-dose MK-677
  • CJC 2x/week, Ipa daily, MK nightly
  • 3–5× baseline with sustained IGF-1
  • Moderate
  • Very High. Combines pulsatile and sustained elevation
  • Recovery-Focused Stack
  • BPC-157 + TB-500 + GHRH analog
  • BPC/TB daily, GHRH 2x/week
  • 2–3× baseline
  • None
  • High for injury-prone individuals or high training volume
  • Professional Assessment
  • For pure recomposition (fat loss + muscle gain simultaneously), the synergistic GHRH + ghrelin stack outperforms monotherapy by maintaining anabolic signalling during caloric deficits without excessive appetite disruption. Recovery peptides amplify training volume capacity, which indirectly drives recomposition through increased stimulus.