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Best Peptides for Body Recomposition: Protocol Comparison
The table below compares the most effective peptide protocols for body recomposition based on mechanism, dosing logistics, and expected outcomes over a 12-week cycle. CJC-1295/Ipamorelin GHRH/GHRP synergy. Pulsatile GH/IGF-1 elevation 200–300mcg each, SubQ, ni
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- The table below compares the most effective peptide protocols for body recomposition based on mechanism, dosing logistics, and expected outcomes over a 12-week cycle.
- CJC-1295/Ipamorelin
- GHRH/GHRP synergy. Pulsatile GH/IGF-1 elevation
- 200–300mcg each, SubQ, nightly
- +1.5–3kg lean mass, −2–4kg fat mass
- Neutral to mild increase
- Gold standard for balanced recomposition. Mimics natural GH physiology with minimal side effects
- MK-677 (Ibutamoren)
- Oral ghrelin mimetic. Sustained 24hr GH/IGF-1 elevation
- 15–25mg oral, once daily
- +1–2kg lean mass, −1–3kg fat mass
- Significant increase (60–70% of users)
- Convenient but appetite stimulation makes caloric control difficult. Best for lean bulking rather than pure recomposition
- Tesamorelin
- Selective GHRH analog. Targets visceral adipose tissue
- 2mg SubQ daily
- +0.5–1.5kg lean mass, −2–5kg visceral fat
- Neutral
- Best choice for individuals with elevated waist circumference and metabolic dysfunction. Precise, predictable
- AOD-9604
- GH fragment. Lipolysis without GH receptor activation
- 250–500mcg SubQ daily fasted
- Minimal lean mass change, −1–2kg fat mass
- Pure fat-loss agent with no systemic effects. Ideal for final cut phase or stacking with anabolic peptides
- MOTS-c
- Mitochondrial peptide. AMPK activation, insulin sensitization
- 5–10mg SubQ 2–3×/week
- Minimal lean mass change, −1–3kg fat mass
- Long-term metabolic optimizer. Improves nutrient partitioning and insulin sensitivity over months
- Tesofensine
- Triple monoamine reuptake inhibitor. Thermogenesis + appetite suppression
- 0.25–0.5mg oral daily
- Minimal lean mass change, −4–7kg fat mass
- Strong decrease
- Most potent fat-loss agent available. Requires cardiovascular screening, stimulant profile limits tolerability
- BPC-157 + TB-500
- Tissue repair, angiogenesis, anti-inflammatory signaling
- BPC-157: 250–500mcg daily; TB-500: 2–5mg 2×/week
- No direct body composition effect
- Enables training consistency and volume. Indirect but essential for recomposition success