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Peptide Therapy GuideClear peptide education

Understand the source comparison

How to Use Peptides for Fat Burning: Protocol Comparison

Before starting any peptide regimen, understand that different compounds require different administration strategies based on half-life, receptor dynamics, and stacking compatibility. CJC-1295 (no DAC) GH-releasing hormone analog. Stimulates pituitary GH secre

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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • Before starting any peptide regimen, understand that different compounds require different administration strategies based on half-life, receptor dynamics, and stacking compatibility.
  • CJC-1295 (no DAC)
  • GH-releasing hormone analog. Stimulates pituitary GH secretion
  • 100–200 mcg per injection
  • 1–3 times daily, fasted state
  • ~30 minutes
  • Short half-life requires frequent dosing but allows precise control over GH pulses; often stacked with a GHRP
  • CJC-1295 with DAC
  • Extended-release GHRH analog. Sustained GH elevation
  • 2 mg per week
  • Once weekly, any time
  • 6–8 days
  • Sustained GH release over days reduces injection frequency; may blunt natural pulsatile GH secretion if used long-term
  • Ipamorelin
  • GHRP. Selective ghrelin receptor agonist
  • 200–300 mcg per injection
  • 2–3 times daily, fasted
  • ~2 hours
  • Minimal impact on cortisol or prolactin; synergizes with CJC-1295; short half-life limits convenience
  • Tesofensine
  • Triple monoamine reuptake inhibitor
  • 0.25–1.0 mg daily
  • Once daily, morning
  • Not a peptide but often grouped in fat-loss research; acts centrally on appetite and energy expenditure; highest weight loss magnitude in trials
  • Hexarelin
  • Potent GHRP. Strongest GH pulse amplitude
  • 100 mcg per injection
  • 1–2 times daily, fasted
  • ~70 minutes
  • Strongest GH response but rapid desensitization after 10–16 weeks; cortisol elevation noted at higher doses