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Best Glutathione Dosage Liver Health 2026: Dosing Comparison
The table below compares dosing strategies, expected bioavailability, and clinical context for different glutathione supplementation methods. Liposomal GSH 500–1000mg 30–40% 8–12 weeks for ALT/AST reduction $60–$120 Highest oral bioavailability. Worth the prem
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- The table below compares dosing strategies, expected bioavailability, and clinical context for different glutathione supplementation methods.
- Liposomal GSH
- 500–1000mg
- 30–40%
- 8–12 weeks for ALT/AST reduction
- $60–$120
- Highest oral bioavailability. Worth the premium if compliance is high
- Sublingual Reduced GSH
- 500–750mg
- 15–25%
- 10–14 weeks
- $40–$80
- Moderate bioavailability. Viable alternative if liposomal cost is prohibitive
- Standard Oral Capsules (non-liposomal)
- <10%
- Minimal to no effect
- $20–$50
- Low bioavailability makes this cost-ineffective despite lower price
- N-Acetylcysteine (Precursor)
- 600–1200mg
- Indirect (cysteine absorbed at ~70%)
- 6–10 weeks for endogenous GSH elevation
- $15–$35
- Most cost-effective strategy. Supports hepatic synthesis rather than replacement
- Intravenous Glutathione
- 600–1200mg per session (1–3×/week)
- ~100%
- 4–8 weeks with consistent sessions
- $200–$600
- Highest bioavailability but requires clinical access. Reserve for acute hepatic distress