Understand the source comparison
Best Glutathione Dosage Heavy Metal Detox 2026: Protocol Comparison
Low-Burden Maintenance 500mg daily Liposomal or sublingual NAC 600mg, Selenium 200mcg 12–16 weeks minimum <5% (mild GI) Best for environmental exposure without documented high burden. Balances efficacy and tolerability Moderate-Burden Active Detox 1000mg split
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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- Low-Burden Maintenance
- 500mg daily
- Liposomal or sublingual
- NAC 600mg, Selenium 200mcg
- 12–16 weeks minimum
- <5% (mild GI)
- Best for environmental exposure without documented high burden. Balances efficacy and tolerability
- Moderate-Burden Active Detox
- 1000mg split twice daily
- Liposomal preferred
- NAC 1200mg, Selenium 200mcg, Methylated B complex
- 16–24 weeks
- 8–12% (nausea, sulfur taste)
- Standard evidence-based protocol for blood mercury 5–10mcg/L or lead 10–25mcg/dL
- High-Burden Supervised
- 1500–2000mg split twice daily
- Liposomal or IV pulse
- NAC 1800mg, Selenium 400mcg, Methylated B12/folate, Magnesium glycinate
- 24+ weeks with monitoring
- 15–25% (GI distress, fatigue during mobilisation)
- Reserved for occupational exposure or documented organ burden. Requires physician oversight and serial lab monitoring
- IV Pulse Protocol
- 1000–2000mg per infusion
- Intravenous push
- Oral maintenance between infusions (500–1000mg daily)
- Weekly or biweekly for 8–12 weeks
- <10% infusion site reactions
- Fastest mobilisation but not sustainable long-term. Best used to initiate detox before transitioning to oral maintenance