Isntree TW-Real Bifida Ampoule Versus Estée Lauder Advanced Night Repair Synchronized Recovery Complex II

Isntree TW-Real Bifida Ampoule Versus Estée Lauder Advanced Night Repair Synchronized Recovery Complex II

This barrier-repair ampoule is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and soften the look of wrinkles.

This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Bifida Ferment Lysate

Dipropylene Glycol

Niacinamide

Glycerin

Lactobacillus/Pumpkin Ferment Extract

Lactobacillus/Soybean Ferment Extract

Rice Ferment Filtrate

Sodium Hyaluronate

Hydrolyzed Collagen

Salix Alba Bark Extract

Origanum Vulgare Leaf Extract

Cinnamomum Zeylanicum Bark Extract

Portulaca Oleracea Extract

Chamaecyparis Obtusa Leaf Extract

Beta-Glucan

Palmitoyl Oligopeptide

Copper Tripeptide-1

Acetyl Hexapeptide-8

Allantoin

Hydroxyethylcellulose

Panthenol

Carbomer

Arginine

Butylene Glycol

Scutellaria Baicalensis Root Extract

Illicium Verum Fruit Extract

Adenosine

1,2-Hexanediol

Disodium EDTA

Bifida Ferment Lysate, Dipropylene Glycol, Niacinamide, Glycerin, Lactobacillus/Pumpkin Ferment Extract, Lactobacillus/Soybean Ferment Extract, Rice Ferment Filtrate, Sodium Hyaluronate, Hydrolyzed Collagen, Salix Alba Bark Extract, Origanum Vulgare Leaf Extract, Cinnamomum Zeylanicum Bark Extract, Portulaca Oleracea Extract, Chamaecyparis Obtusa Leaf Extract, Beta-Glucan, Palmitoyl Oligopeptide, Copper Tripeptide-1, Acetyl Hexapeptide-8, Allantoin, Hydroxyethylcellulose, Panthenol, Carbomer, Arginine, Butylene Glycol, Scutellaria Baicalensis Root Extract, Illicium Verum Fruit Extract, Adenosine, 1,2-Hexanediol, Disodium EDTA

Water

Methyl Gluceth-20

PEG-75

Bis-PEG-18 Methyl Ether Dimethyl Silane

Propanediol

Cola Acuminata Seed Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Tripeptide-32

Ethylhexylglycerin

Sodium Rna

Bisabolol

Glycereth-26

Squalane

Oleth-3 Phosphate

Caprylyl Glycol

Lactobacillus Ferment

Oleth-3

Oleth-5

Anthemis Nobilis Flower Extract

Faex Extract

Choleth-24

Hydrogenated Lecithin

Ceteth-24

Tocopheryl Acetate

Ethylhexyl Methoxycinnamate

Hexylene Glycol

Triethanolamine

Trisodium EDTA

BHT

Xanthan Gum

Phenoxyethanol

CI 14700

CI 19140

Water, Bifida Ferment Lysate, Methyl Gluceth-20, PEG-75, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Propanediol, Cola Acuminata Seed Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Tripeptide-32, Ethylhexylglycerin, Sodium Rna, Bisabolol, Glycereth-26, Squalane, Sodium Hyaluronate, Oleth-3 Phosphate, Caprylyl Glycol, Lactobacillus Ferment, Oleth-3, Oleth-5, Anthemis Nobilis Flower Extract, Faex Extract, Choleth-24, Hydrogenated Lecithin, Ceteth-24, Tocopheryl Acetate, Ethylhexyl Methoxycinnamate, Hexylene Glycol, Carbomer, Triethanolamine, Trisodium EDTA, BHT, Xanthan Gum, Phenoxyethanol, CI 14700, CI 19140

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bifida Ferment Lysate is a postbiotic ingredient made by fermenting Bifidobacterium to extract a nutrient-rich mix of peptides, amino acids, vitamins, organic acids, and polysaccharides.

These components are basically the building blocks that your skin already uses to stay hydrated, repair itself, and maintain its barrier. That's why this ingredient helps your skin hold onto moisture and stay resilient against irritation.

One in-vitro study found that this ingredient tells your skin cells to produce more of the proteins (filaggrin, loricrin, and involucrin) for building a strong and healthy barrier. This study also found this ingredient to be a solid antioxidant that helped neutralize damage against UV and pollution.

A study with people from 2010 found that sensitive, reactive skin using a cream with 10% of this ingredient for a month became noticeably less dry, less reactive, and harder to irritate compared to the group using a plain cream.

In short, this ingredient is a well-tolerated ingredient that can help with barrier repair, antioxidant protection, and calming reactive skin.

This ingredient is generally considered fungal acne (Malassezia) safe; Bifidobacterium is a bacterium, not a yeast or fungus.

The fungal acne concern with fermented ingredients mainly applies to yeast-derived ferments like Saccharomyces and Galactomyces, because those are in the same kingdom as Malassezia and could theoretically contain residual compounds that feed it.

Bifida is a completely different organism, so on its own it doesn't provide a food source for the Malassezia yeast that causes fungal acne.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

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