synpep table FAQ

If you or someone else has taken too much naproxen/esomeprazole, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure that you discuss if you are using any of the following before taking naproxen/esomeprazole.

The most common side effects of naproxen/esomeprazole are listed below. Tell your health care provider if you have any of these side effects that bother you.

Allergies to Ingredients. People who are allergic to any of the following should not take naproxen/esomeprazole.

Naproxen/esomeprazole is a combination medicine that is commonly used to treat pain, swelling, and discomfort caused by osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and juvenile idiopathic arthritis. Esomeprazole reduces the risk of stomach ulcers from naproxen. Naproxen/esomeprazole may also be used for other conditions as determined by your health care provider.

Naproxen/esomeprazole should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C), for shorter periods of time, such as when transporting it. Store in a cool, dry place in a tightly closed container.

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if naproxen/esomeprazole is right for you. In particular, make sure that you discuss any of the following. Current and Past Health Conditions. Tell your health care provider if you have any of the following.

Naproxen works by blocking certain substances in the body that cause pain, inflammation, and fever. Esomeprazole reduces acid secretion and protects the stomach from acid-related problems.

Do not take naproxen/esomeprazole unless it has been prescribed to you by a health care provider. Take it as prescribed. Do not share naproxen/esomeprazole with other people, even if they have the same condition as you. It may harm them. Keep naproxen/esomeprazole out of the reach of children. Take naproxen/esomeprazole at least 30 minutes before a meal. Swallow naproxen/esomeprazole whole with liquid. Do not split, chew, crush, or dissolve. You may use antacids while taking naproxen/esomeprazole. People aged 65 years and older may be at a greater risk for some side effects of naproxen/esomeprazole. Talk to your health care provider about your risks if you are in this age group.

While less common, the most serious side effects of naproxen/esomeprazole are described below, along with what to do if they happen. Heart Attack and Stroke. Naproxen/esomeprazole may increase your risk for a heart attack or stroke that can lead to death. This risk is higher in people with existing heart disease and with longer use of naproxen and higher doses. Do not take naproxen if you have had a recent heart attack without talking to your health care provider. This could increase your risk of having another heart attack. Stop taking naproxen and get help right away if you have any of the following symptoms of a heart attack or stroke.

There are no known interactions between naproxen/esomeprazole and foods or drinks. Drinking alcohol while taking naproxen/esomeprazole increases your risk for stomach ulcers and bleeding. It is best to limit the amount of alcohol you drink.