setmelanotide uses FAQ

There are no known interactions between Imcivree and foods or drinks. There are no known interactions between Imcivree and alcohol.

If you or someone else has used too much Imcivree, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Imcivree is right for you. In particular, make sure that you discuss any of the following. Adrenal Insufficiency. If you have acquired hypothalamic obesity and adrenal insufficiency you may be at higher risk of having acute adrenal insufficiency while using Imcivree. Tell your health care provider right away if you have fever, other signs of infection, or changes in how tired you feel, energy levels, mental function, or dizziness. Your health care provider may need to start or increase your steroid medicine dose while you are using Imcivree. Diabetes Insipidus. If you have acquired hypothalamic obesity and central diabetes insipidus you may be at higher risk of changes in your sodium blood levels while using Imcivree. Your health care provider may need to monitor your sodium levels more frequently, especially if you have changes in how much liquid you drink each day or your hydration status. Tell your health care provider if you have severe nausea and vomiting, changes in how much you are drinking, or any of the following signs of dehydration.

For more information about Imcivree, you can visit the drugmaker’s website at www.imcivree.com or call them at 857-264-4280.

Allergies to Ingredients. People who are allergic to any of the following should not use Imcivree.

The most common side effects of Imcivree are listed below. Tell your health care provider if you have any of these side effects that bother you.

Imcivree activates a specific receptor in the body called the melanocortin 4 (MC4) receptor, which is thought to decrease hunger and promote weight loss by decreasing the amount of calories eaten and increasing the amount of energy used by the body. This medicine is only for certain people with conditions where the MC4 receptor is not activated enough. You will likely have a genetic test to confirm that you may benefit from this medicine.

There are no known interactions between Imcivree and other medicines. Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using.

Imcivree (setmelanotide) is commonly used to help lose weight and maintain weight loss in certain people with obesity caused by the following conditions.

If you miss a dose of Imcivree, use your next dose at the regularly scheduled time the next day. Do not use double or extra doses.

While less common, the most serious side effects of Imcivree are described below, along with what to do if they happen. Severe Allergic Reactions. Imcivree may cause allergic reactions, which can be serious. Stop using Imcivree and get help right away if you have any of the following symptoms of a serious allergic reaction.

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Unopened Imcivree should be stored in the original carton in the refrigerator, between 36 F and 46 F (2 C and 8 C). Unopened Imcivree may also be stored for up to 30 days at room temperature, between 36 F and 77 F (2 C and 25 C). It can be exposed to temperatures up to 86 F (30 C) for shorter periods of time, such as when transporting it. Throw away Imcivree 30 days after it is punctured, opened, or first removed from the refrigerator.

Do not use Imcivree unless it has been prescribed to you by a health care provider. Use it as prescribed. Do not share Imcivree with other people, even if they have the same condition as you. It may harm them. Keep Imcivree out of the reach of children. If this medicine is kept in a refrigerator, take special precautions to keep it away from children who also use the refrigerator. Imcivree is an injection given under the skin of the belly, upper arm, or thigh. Imcivree should not be injected into painful, damaged, or infected areas of skin. Make sure that you or a caregiver understands how to properly prepare and use Imcivree. Read the “Instructions for Use” that comes with your medicine. If you have any questions, talk to your health care provider.