ruxolitinib other names FAQ

Jakafi should be stored at room temperature, between 68 F and 77 F (20 C and 25 C). It can be exposed to temperatures between 59 F and 86 F (15 C and 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place. Protect Jakafi from light.

There are no known interactions between Jakafi and foods or drinks. It is unknown if drinking alcohol will affect Jakafi. The risk of dizziness may be increased if you drink alcohol while taking Jakafi.

Jakafi (ruxolitinib) is commonly used to treat certain types of blood cancers, including myelofibrosis (MF) and polycythemia vera. It is also used to treat graft versus host disease (GVHD). Your Guide to Jakafi for Polycythemia Vera: What You Need to Know Jakafi may also be used for other conditions as determined by your health care provider.

Tell your health care provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them know if Jakafi is right for you. In particular, make sure that you discuss any of the following. Current and Past Health Conditions. Tell your health care provider if you have any of the following.

Do not take Jakafi unless it has been prescribed to you by a health care provider. Take it as prescribed. Do not share Jakafi with other people, even if they have the same condition as you. It may harm them. Keep Jakafi out of the reach of children. Attend all appointments with your health care provider so they can do blood tests to make sure Jakafi is safe for you to take. If you are unable to swallow Jakafi and have a nasogastric tube, ask your health care provider how to take the medicine. Do not stop taking Jakafi without talking to your health care provider. Stopping Jakafi suddenly can cause symptoms of your condition to return. These symptoms can be dangerous and even life-threatening. If you need to stop taking Jakafi, your health care provider will give you instructions on how to stop the medicine. If you have kidney problems and are on dialysis, you should not take your Jakafi dose before your dialysis. Take Jakafi after you have completed dialysis.

If you or someone else has used too much Jakafi, get medical help right away, call 911, or contact a Poison Control center at 800-222-1222.

While less common, the most serious side effects of Jakafi are described below, along with what to do if they happen. Severe Allergic Reactions. Jakafi may cause allergic reactions, which can be serious. Stop taking Jakafi and get help right away if you have any of the following symptoms of a serious allergic reaction.

Jakafi is a type of medicine known as a JAK inhibitor. It inhibits specific kinases called Janus associated kinase 1 and 2 (JAK1 and JAK2). Janus associated kinases (JAKs) are proteins that become overactive in blood cancer and can cause your body to make blood cells that are not healthy. Jakafi blocks the action of JAK1 and JAK2 to slow down the creation of blood cells that are not normal. It also blocks JAK from sending certain signals that can cause GVHD. Jakafi blocks these signals to treat GVHD.

The most common side effects of Jakafi are listed below. Tell your health care provider if you have any of these side effects that bother you.

If you miss a dose, skip the missed dose and only take the next dose. Do not take double or extra doses.

Always tell your health care provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. In particular, make sure that you discuss if you are taking fluconazole, which is a medicine used to treat fungal or yeast infections. Many other medicines may alter the blood levels of Jakafi. Tell your health care provider about all medicines that you take or have recently taken. This may not be a complete list of medicines that can interact with Jakafi. Always check with your health care provider.

Allergies to Ingredients. People who are allergic to any of the following should not take Jakafi.

For more information about Jakafi, you can visit the drugmaker’s website www.jakafi.com or call them at 855-452-5234.