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Macrocyclic peptides – unlocking the power of macrocycles In modern drug discovery macrocyclic peptides are breaking boundaries. Since the inception of RG Discovery, we have had a strong focus on peptide chemi…
Read guide →Innovation Merck scientists are exploring macrocyclic peptides, a new way to combine the properties of a biologic in a pill. September 15, 2025 Small molecules, generally taken as pills, make up nearly 90% of …
Read guide →Macrocyclic peptides have emerged as a compelling therapeutic modality for difficult protein targets, and mRNA display technologies now allow researchers to screen libraries exceeding one trillion unique seque…
Read guide →Introduction Peptides are emerging therapeutics, filling the gap between small molecular drugs and antibodies 1, 2. Historically, peptide drugs are developed from naturally occurring bioactive peptides such as…
Read guide →Reports claim that the development of peptide-based therapeutics, from discovery to commercial launch, can take approximately 10 to 15 years. Consequently, research has been centred around accelerating the pre…
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