Plecanatide FAQ

Unless your doctor tells you otherwise, continue your normal diet.

Plecanatide comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take plecanatide at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take plecanatide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Remove and discard the polyester coil (used to protect the tablets during shipping) after opening the bottle. Do not remove the desiccant (drying agent) from the bottle, if one has been provided.

Plecanatide is used in adults to treat chronic idiopathic constipation (CIC; difficult or infrequent passage of stools that lasts for 3 months or longer and is not caused by a disease or a medication) and irritable bowel syndrome with constipation (IBS-C; a condition that causes stomach pain or cramps, bloating, and constipation.) Plecanatide is in a class of medications called guanylate cyclase-C agonists. It works by increasing the movement of food and waste through the stomach and intestines.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.