Topic resource collection
Approved comparison material connected to this topic.
6 resourcesRead both sides
BPC-157 Angiogenesis + collagen synthesis Moderate. Promotes healing in multiple tissues High. Restores tight junctions, reduces mucosal lesions Strong (multiple animal studies, limited human data) Best barrier-repair peptide wit…
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid sequence derived from gastric juice protein BPC. It promotes angiogenesis through VEGF (vascular endothelial growth factor) upregulation and accelerates collagen…
Ghrelin agonists (MK-677) Motilin receptor activation, MMC cycling restoration Moderate. Mechanistic studies in healthy subjects, no SIBO trials 10–25mg oral daily No controlled SIBO outcomes, variable individual response Stronge…
BPC-157 Epithelial repair, angiogenesis VEGF upregulation, NOS stabilisation Rodent models: 60% faster healing; human case reports positive 250–500 mcg SC daily Most relevant for barrier dysfunction SIBO LL-37 Antimicrobial membr…
LL-37 (Cathelicidin) Direct antimicrobial activity via bacterial membrane disruption MIC against E. coli and Enterococcus at 2–8 μg/mL; SIBO patients show 58% reduced LL-37 expression Not available as exogenous peptide; upregulat…
BPC-157 VEGF-mediated angiogenesis, tight junction protein upregulation Restores occludin and ZO-1 expression, reduces permeability by 40–60% in 72 hours Modest. Reduces neutrophil infiltration, limited direct immune modulation A…