peptides for low platelets FAQ

According to clinical studies, Nplate worked to increase platelet levels in as little as 2 weeks after starting the medicine. You or your child may notice less bleeding or bruising as your platelet levels go up. Your health care provider may monitor your platelets through blood tests while you are receiving Nplate. Based on this, your health care provider can find out how Nplate is working for you, if more medicine needs to be added, or if you may need to switch to a new medicine altogether.

There currently are no noted drug interactions with Nplate. But it is important to avoid taking medicines that can increase your risk of bleeding and to avoid situations where you may hurt yourself while you are receiving Nplate. Always tell your health care provider about all your or your child’s prescription and over-the-counter medicines, and supplements, including any changes to your or your child’s medicines. Your health care provider will decide if any of the medicines you or your child is taking can increase the risk of bleeding.

The drugmaker offers a program that may make you eligible to pay as little as $0 for you or your child’s Nplate prescription. Whether you are eligible depends on the type of health insurance you or your child has. You can find out more information by calling 866-264-2778 or by visiting www.nplate.com/support#financial-assistance-container.

Nplate is given as a shot under the skin. It will be given to you or your child by a health care provider once a week. Your dose will generally depend on your weight. Your health care provider may adjust your dose depending on how well the medicine is working to increase your platelet count. Try to keep all appointments with your health care provider. If you miss a dose of Nplate, call your health care provider right away to reschedule your next dose.

The most common side effects seen with Nplate in adults are listed below.

There is no cure for ITP. Its symptoms can vary from person to person, with some people not having any symptoms. Because ITP causes low platelets, the main side effects that you or your child may have are bleeding problems, which may show up in different ways as listed below.

Multiple clinical trials were done in adults and children to test the efficacy and safety of Nplate. Adults Studies 1 and 2 included people who had tried at least one medicine for their ITP and had a platelet count of 30 billion cells per liter or less. Study 1 included people who had not had their spleen removed, while Study 2 included people who had their spleen removed. People in the study either received Nplate or a placebo containing no medicine every week for 24 weeks. Researchers measured how well people responded to Nplate based on their platelet count. In this study, it was defined as the percentage of people who had a platelet count of 50 billion cells per liter or more for at least 6 of the last 8 weeks of treatment. The study included White people (82%), Black people (7%), Hispanic or Latino people (6%), and those classified as “Other” (5%), which included Asian people and Native Hawaiians or other Pacific Islanders. The average age of people in the study was 52 years old, and a higher number of people in the study were women (65%). Study 3 included people who had tried at least one first-line medicine for their ITP and had a platelet count of 30 billion cells per liter or less. Researchers measured how well people responded to Nplate based on their platelet count. In this study, it was defined as the number of months in which people had a platelet count of 50 billion cells per liter or more while receiving Nplate over a 12-month period. The study included White people, Black people, and Asian people, with a majority of people in the study being White. The median age was 39 years old, and a higher number of people in the study were women (59%). Children Study 4 included children who were 1 to 17 years of age who had tried at least one medicine for their ITP and had a platelet count of 30 billion cells per liter or less. The children in the study received either Nplate or a placebo for 24 weeks. Researchers measured how well the children responded to Nplate based on their platelet count. In this study, it was defined as the percentage of children with a platelet count of 50 billion cells per liter or more for at least 6 of the last 8 weeks of treatment. The study included White people (75%), Black people (10%), Asian people (10%), and those classified as “Other” (5%). A higher number of children in the study were girls (56%), and the median age was around 10 years old. Study 5 included children who were 1 to 17 years of age who had a platelet count of 30 billion cells per liter or less. The children in the study received either Nplate or a placebo for 12 weeks. Researchers measured how well the children responded to Nplate based on their platelet count. In this study, it was defined as the percentage of children who had a platelet count of 50 billion cells per liter or more for 2 consecutive weeks. The study included White people (59%), Black people (23%), Hispanic or Latino people (14%), and those classified as “Other” (5%). A higher number of children in the study were boys (73%), and the median age was 10 years old. Study 6 included children who were 1 to 17 years of age who had tried at least one medicine for their ITP. The children in the study received Nplate. The study looked to see the time children had a platelet response, which was defined as 50 billion cells per liter or more, during the first 6 months of treatment. The study included White people (81%), Black people (5%), Asian people (6%), and those classified as “Other” (8%). The median age was 10 years old.