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Thymalin Restores CD4+CD25+Foxp3+ T-regulatory cell differentiation from thymic progenitors Sechenov trial: 38% anti-TPO reduction at 12 weeks in 84 patients with active Hashimoto's 10mg IM daily × 10 days, then 10mg IM twice wee…
Thymosin Alpha-1 T-regulatory cell upregulation, Treg/Th17 rebalancing Direct (restores immune tolerance) Indirect (reduces ongoing damage) Minimal direct effect Phase 2 human trials in autoimmune thyroiditis BPC-157 VEGF/FGF-2 u…
Thymalin T-cell modulation; Treg upregulation Moderate (Eastern European clinical trials) 5–10mg subcutaneous, 2–3 times weekly 22–34% reduction in anti-TPO titres over 12 weeks in 2018 study Strongest evidence for immune recalib…