peptides for fertility FAQ

Idiopathic oligospermia (sperm count <15 million/mL without anatomical or hormonal abnormality) often reflects subclinical HPG axis dysfunction or local testicular inflammation. Pulsatile gonadorelin can restore spermatogenesis in men with hypogonadotropic hypogonadism. 90% sperm production restoration in 12 months according to Human Reproduction data. For men with normal LH and FSH but low sperm parameters, the mechanism may be local: IGF-1 LR3 enhances Sertoli cell function, and thymosin alpha-1 reduces intratesticular inflammation. No large RCTs exist for these peptides in male infertility, but the mechanistic rationale is strong. Seminal IGF-1 testing can identify men most likely to respond.