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Scientists at the Washington University School of Medicine in St. Louis have developed an immunotherapy to minimize the damage from traumatic spinal cord injury. Their findings in mice show that immunotherapy …
Read guide →A calorie-restricted diet is often said to enhance longevity. Less frequently discussed, and poorly understood, is why fasting should slow aging or delay the loss of tissue function associated with aging. To b…
Read guide →mRNA 3′ UTRs have hundreds of highly conserved nucleotides, but their biological roles are unclear. In a new study published in Cell titled, “mRNA 3′ UTRs chaperone intrinsically disordered regions to control …
Read guide →Going the full distance is the least any messenger can do. A messenger should also retain enough vigor to ensure that its message is heard and, if possible, heeded. For an inspirational example, look at Pheidi…
Read guide →UCB plans to acquire Ra Pharmaceuticals for approximately $2.1 billion, the companies said today, in a deal designed to expand the buyer’s presence in rare disease therapeutics by adding to its pipeline Ra Pha…
Read guide →Mirna Therapeutics today said it has initiated a Phase I clinical trial for its microRNA-based cancer candidate MRX34, making it the first miRNA to advance into such study for cancer. MRX34 is an miRNA mimic o…
Read guide →Chiesi Farmaceutici and Aptuit have initiated a joint project aimed at identifying compounds for the potential treatment of idiopathic pulmonary fibrosis (IPF). Under terms of the agreement, both parties will …
Read guide →Prime Medicine which applies a “search and replace” approach to gene editing, has disclosed plans to go public through an initial public offering (IPO) whose value has been speculated may reach $200 million—no…
Read guide →Scientists have inserted mRNA into mesenchymal stem cells (MSCs) to produce a drug delivery vehicle. Following systemic administration, the modified MSCs targeted and adhered to sites of inflammation, then rel…
Read guide →Voltaire argued, “Perfection is attained by slow degrees; it requires the hand of time.” However, in drug discovery projects, perfection can’t be attained soon enough. A project to develop a perfect drug, or a…
Read guide →March 1, 2007 (Vol. 27, No. 5) With the introduction of fluorogenic probes and fluorometric thermal cyclers that enable the monitoring of amplification reactions in real time, the sensitivity and precision of …
Read guide →HPV OncoTect is available in Europe, South America, and South Asia to detect progression to cervical cancer. IncellDx closed a $3 million Series A financing round that will help advance its HPV OncoTect test. …
Read guide →Companies will be looking for therapeutic proteins using Envoy’s bacTRAP platform. Takeda Pharmaceutical is initially paying Envoy Therapeutics $3 million under a three-year research alliance aimed at discover…
Read guide →Johnson & Johnson’s Janssen Biotech will use Isis Pharmaceuticals’ RNA-targeted technology platform to discover and develop antisense drugs to treat autoimmune disorders of the gastrointestinal (GI) tract, in …
Read guide →Money will go toward a Phase III study in nonsense mutation cystic fibrosis. PTC Therapeutics obtained a $1.6 million grant from the FDA Office of Orphan Products Development to support a Phase III study of at…
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