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Old molecules and new complexes: Hollings Cancer Center researchers at the Medical University of South Carolina (MUSC) have discovered cell membrane complexes called ceramidosomes that may be a new target for …
Read guide →Research article Open archive Abstract Antimicrobial peptides (AMPs) have received considerable interest as a source of new antibiotics with the potential for treatment of multiple-drug resistant infections. A…
Read guide →Abstract Peptides comprise a versatile class of biomolecules that present a unique chemical space with diverse physicochemical and structural properties. Some classes of peptides are able to naturally cross th…
Read guide →Melittin-loaded nanoparticle synthesis and action on cancer cells in vitro. The chemical synthesis of melittin-loaded nanoparticle complexes has been described earlier ( 19 ). When melittin is incorporated int…
Read guide →Research article Open archive Author links open overlay panel , , , , Highlights • Bioactivity of membrane-active peptides is not merely due to their binding to the membrane. • Oligomer formation and molecular…
Read guide →© 2024 by the Association of Clinical Scientists, Inc. Victor Adler 3 , Richard D. Feinman 2 , Anna Miller 2 , Miriam Silberstein 3 , Ehsan Yazdi 4 ⇑ and Matthew R. Pincus 1 ⇑ 1 Department of Pathology, Brookl…
Read guide →Introduction In search for novel and more efficacious anticancer therapeutics, many positively charged antimicrobial peptides (AMPs) have surfaced as promising agents because they can kill cancer cells by pref…
Read guide →Skip to main content Skip to article View PDF Under a Creative Commons license Open access Abstract Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or anticarcinogens that present a gene…
Read guide →Abstract Membrane-disruptive peptides/peptidomimetics (MDPs) are antimicrobials or anticarcinogens that present a general killing mechanism through the physical disruption of cell membranes, in contrast to con…
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