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Nephrilin peptides have proven to have several beneficial systemic effects in rodent models of stress, burn, and sepsis by reducing present pro-inflammatory factors. Scientists in Sunnyvale, CA were keen on te…
Read guide →Peptide design is a delicate balance of structure, function, and stability. One critical yet often overlooked element is the spacer, a molecular linker that separates functional groups or enhances peptide perf…
Read guide →When it comes to the world of peptide research, the selection of appropriate fluorescent dyes is crucial for various applications, including cellular imaging, molecular diagnostics, and therapeutic interventio…
Read guide →LifeTein Referral Rewards Program Refer a colleague. Strengthen your research network. Get rewarded. At LifeTein, many of our strongest collaborations begin with referrals from trusted scientists like you. To …
Read guide →The folate receptor alpha (FRα) is highly expressed in ovarian cancer and not in normal tissues. An FRα binding peptide C7 (Met-His-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser, MHTAPGWGYRLS) was found to bind to F…
Read guide →A tumor-penetrating peptide, iRGD, was synthesized by LifeTein. It was found that iRGD improves tumor-specific penetration of intraperitoneal compounds and enhances intraperitoneal chemotherapy (IPC) in mice. …
Read guide →Peptide protein binding strategies: Structure, Volume 18, Issue 2, 188-199, 10 February 2010 Peptide-Protein Binding Highlights After binding its partners, most peptides do not introduce any conformational cha…
Read guide →Deuterated peptides represent a significant advancement in the field of drug development and structural characterization. These molecules, where one or more of the hydrogen atoms have been replaced by its heav…
Read guide →Peptides can be used for ELISA assay. A peptide-based indirect ELISA was used to screen a population of 40 Multiple sclerosis patients and 39 healthy controls. The encephalitogenic myelin oligodendrocyte glyco…
Read guide →Stapled peptides represent a significant advancement in the field of therapeutic peptides, offering enhanced stability, specificity, and cellular uptake compared to their linear counterparts. This innovative a…
Read guide →Hydrogels with a capacity to absorb and hold water within a porous, swelled structure make it a great candidate as a drug delivery system due to their broad range of physical properties as well as chemical ada…
Read guide →Cell-penetrating peptides (CPPs) have transformed biomedical research by facilitating the delivery of therapeutic and diagnostic agents across cellular membranes. Among these, the RGD peptide (Arg-Gly-Asp) has…
Read guide →Protein-protein interactions (PPI) are highly specific electrostatic attractions between protein structures. The interactions regulate cell function and influence physiology and development. Mass spectrometry …
Read guide →personalized medicine using synthetic peptides Interest in personalized treatment has been fuelled by the concept of tailoring therapy with the best response and highest safety margin to ensure better patient …
Read guide →There are many ways to design improved peptides: site-directed mutagenesis, computational design approaches, synthetic libraries, template-assisted methodologies, and mechanism-based strategies. Site-directed …
Read guide →Peptide conjugation magnetic beads are powerful tools in biotechnology and molecular biology. They facilitate the covalent attachment of peptides to a magnetic core, enabling efficient separation and purificat…
Read guide →Peptide nucleic acids (PNAs) are synthetic mimics of DNA. The deoxyribose phosphate backbone of PNAs is replaced by a pseudo-peptide polymer. These specific physicochemical properties are exploited to develop …
Read guide →Antimicrobial peptides (AMPs) represent promising alternatives to conventional antibiotics. These antimicrobial peptides form pores by interaction with the peptide and lipid from bacterial membranes. Thus, AMP…
Read guide →Check the cancer peptide database for a list of tumor peptides. Tumor antigens can be classified into two categories based on their expression pattern: tumor-specific antigens (TSA) and tumor-associated antige…
Read guide →Bioactive peptides have potential as drug leads. However, one of the peptides’ limitations is their poor stability. One solution is to graft peptides onto suitable molecular scaffolds. When the peptide scaffol…
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