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Antibody screening has enjoyed considerable success in finding antibodies that can grasp disease-associated targets and contribute to therapeutic applications. For example, since the mid-1980s, slightly over 1…
Read guide →The company will screen 700 compounds to obtain in vitro assay data. Caliper Life Sciences has been awarded $2.9 million under the EPA’s ToxCast screening program to evaluate 700 environmental compounds. Separ…
Read guide →Cryo-electron microscopy (cryo-EM) has advanced rapidly in the past few years, positioning itself as an invaluable tool for the pharmaceutical industry. Nobel Laureate Richard Henderson predicted that by 2024,…
Read guide →While G-protein coupled receptors (GPCRs) have shown to be one of the most successful classes of druggable targets in the human genome—with estimates ranging between 30-50% of all medications targeting this cl…
Read guide →The human genome encodes hundreds of G protein-coupled receptors (GPCRs), which form the largest group of receptors that hormones and neurotransmitters exert their functions on our cells. Because of this GPCRs…
Read guide →Researchers at New York University Pain Research Center have identified a mechanism that underlies inflammation and pain in the colon, and demonstrated that in mice with colitis, blocking a key receptor from e…
Read guide →The cell signaling switchboard just got a little bigger and a little more intricate: five orphan receptors and 17 candidate peptide ligands have been found to connect with each other. Also, nine receptors with…
Read guide →Firm claims lipopeptide technology modulates receptors’ intracellular binding sites. Anchor Therapeutics (previously Ascent Therapeutics) secured $10 million in a Series B fundraising led by current investors.…
Read guide →Ortho-McNeil will provide $2.4 million over one-year increment. Ortho-McNeil Pharmaceutical its research agreement with Arena Pharmaceuticals by one year. This is compliant with provisions of the partnership b…
Read guide →DiscoveRx’ cell-based assays will be coupled with Caliper’s LabChip instruments. Caliper Life Sciences and DiscoveRx’ inked an agreement under which DiscoveRx’ functional cell-based GPCR assays will be perform…
Read guide →Receptos’ technology will be used to find small molecule modulators. Receptos and Eli Lilly agreed to research and develop orally delivered small molecule modulators of an undisclosed GPCR target. They will ad…
Read guide →Investor can elect to receive payments from out-licensed products or Compugen shares. Compugen is to receive $5 million in R&D funding from Baize Investments (Israel) to support the development of its pipeline…
Read guide →Cell-based neurotransmitter fluorescent-engineered reporters were used to pinpoint how atypical neuroleptics work, according to study in Nature Neuroscience. Scientists at the University of California, San Die…
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