can peptides cause shingles FAQ

Skin and blood vessel complications of EDS may predispose you to problems with wound healing. This may make you more likely to develop skin infections.

Don’t get the Shingrix vaccine if:

Most complications of EDS affect the skin, muscles, bones, and blood vessels. People with EDS often have skin described as velvety. Skin may be fragile, and wounds may heal slowly. Scars may be thin and discolored and may stretch over time. Rashes are less common but can potentially be a symptom of some types of EDS.

Shingles is a rash caused by varicella zoster, a type of herpes virus that also causes chicken pox. If you’ve had chicken pox, you’re at risk of getting shingles at some point during your lifetime. The first sign of shingles is typically tingling or burning along a particular nerve pathway in the body, progressing to a rash consisting of fluid-filled blisters. Shingles is typically treated with antiviral drugs, over-the-counter pain relievers, and corticosteroids. Healthy people who are treated early usually recover in three to five weeks.

The vaccine Shingrix is available in the U.S, to help prevent shingles. It is the only way to help prevent shingles. Who should get it: The CDC recommends that you get this vaccine if you’re a healthy adult age 50 or older, whether or not you remember having had chickenpox, because most people have been exposed to the virus. The shingles vaccine is also recommended if you are age 19 or older with a weak immune system. How many shots do you need? You would need two shots for Shingrix: One at first, with a follow-up in 2 to 6 months. If you have a weakened immune system, your doctor may want you to get the vaccines closer together. What it does: Shingrix reduces your chance of getting shingles by more than 90%. Even if you still get shingles, the vaccine may help it be less painful. I never had chickenpox. Do I still need the shingles vaccine? Yes, you do. Shingrix is recommended for everyone age 50 or older, whether or not you remember having had chickenpox. If I’ve had shingles, can I still get the vaccine? Yes. It may help prevent another bout of shingles later on. If you have shingles right now, you should wait until the rash is gone before you get vaccinated. What are the side effects? The most common side effects with Shingrix include pain and swelling where the needle went into your skin, muscle pain, tiredness, headache, chills, fever, and stomach troubles. With any vaccine, there is a chance of a severe allergic reaction.

Some studies show that various alternative treatments, from acupuncture to supplements, can offer relief. The research isn’t complete, but some show promise. Check with your doctor before you try any of these: TENS (transcutaneous electrical nerve stimulation). This therapy uses tiny electrical pulses to relieve pain. A TENS unit is about the size of a smartphone and comes with small patches called electrodes. You put them over the painful area and turn the unit on and off as your pain comes and goes. Traditional Chinese medicine. These treatments aim to restore balance in your body. They include acupuncture, the ancient practice of inserting very thin needles into your skin at specific points. Also, moxibustion and cupping, two types of heat therapy, are supposed to draw out toxins. These treatments may be done in combination. Creams and other skin treatments. A mixture of liquid dimethyl sulfoxide (DMSO) and idoxuridine, an antiviral drug, has been proposed as a way to reduce swelling and the number of blisters you have when you put it on your rash. And chlorophyll, the chemical that gives plants their green color, is sometimes used directly on the rash as a cream or saline solution. Supplements. You’ll find a long list of herbs, pills, and oils that claim to relieve shingles. Most have no research to back them up, but there are a couple of exceptions. Papain, a protein found in papayas, is sold in capsules. And manuka and clover honeys can be put directly on your skin. Very early studies on both show they might be helpful.

Small nerve neuropathy, or damage to the small nerve fibers in your skin, is a common feature of EDS. It can cause tingling or burning in your feet or hands and reduced sensitivity to pain and heat.

Shingles is definitely an illness to avoid if you can. Known for its blistering rash, shingles is uncomfortable and sometimes leads to long-lasting complications, including a painful nerve condition called postherpetic neuralgia. While it can affect people of any age, including children, it's most likely to strike after age 60. Shingles is also somewhat unusual. It's caused by a virus that has often been living inside the body for decades. That means it differs from most viral infections in how you get it and how you can prevent it. We asked Michael Starnbach, a professor of microbiology at Harvard Medical School, to answer some common questions about shingles. Below are his responses. Q. How do I get the virus that causes shingles? A. Shingles is caused by the varicella-zoster virus, which you probably encountered decades ago when you got chickenpox as a child. After your chickenpox infection cleared, the virus stuck around. It took up residence in nerve cell clusters in your spine or at the base of your skull. There it stayed dormant, held in check by your immune system. But it can reemerge as shingles. Q. Does everyone who had chickenpox get shingles? A. No. Although anyone who has had chickenpox is at risk for the condition, only an estimated one in three of those people will actually get shingles. It's not clear why some people get it and others don't. It may have something to do with your immune system. If your immune system is compromised by an illness, surgery, or medication, the virus may be able to shake off its slumber and reactivate. When it does, it typically causes a blistering rash, which often appears as a thick stripe across your ribcage or on the side of your face. It may also bring a painful or burning sensation on the skin, headache, fever, and fatigue. Q.Is shingles contagious? A. Yes and no. If you come in close contact with someone who has shingles, you can't catch shingles. But you can be infected with the varicella-zoster virus and develop chickenpox if you aren't vaccinated against the virus and haven't had chickenpox in the past. If you do develop shingles after you were around someone who had a shingles infection, it came from the virus that was already present inside you, not from the new exposure. Q. Can a vaccine trigger shingles? My friend got shingles shortly after receiving her COVID-19 vaccine. Is it just a coincidence? A. There have been anecdotal Internet reports of shingles following both COVID-19 infection and vaccination for COVID-19. But there isn't sufficient statistical or scientific evidence to show a connection. Just because the two events occur near to each other doesn't mean they are related. Any medical intervention, even vaccines as safe as the COVID-19 vaccines, can cause health problems in a very small number of individuals. The vaccine manufacturers and U.S. regulatory agencies track these reactions carefully to determine if there is an association between a particular vaccine and an adverse outcome. Doctors continuously weigh those risks and have uniformly concluded that it is much, much more likely for you to remain healthy if you take the vaccine, despite the super-low risk of an adverse reaction. Q. Can you get shingles more than once? A. Unfortunately, you can. Studies have found that there is approximately a 5% risk of getting a second or a third case of shingles within eight years of your first. This is why doctors recommend that people get the shingles vaccine even if they have already had shingles in the past. Q. How common are complications from shingles? A. A small percentage of people who get shingles experience complications. Approximately 10% to 18% of people develop the nerve pain known as postherpetic neuralgia. About 1% to 4% of people experience other complications that require a hospital stay, such as skin infections or eye-related problems. Q. Is there a cure for shingles? A. No, nothing can cure a shingles attack. However, antiviral medications may help you recover more quickly and reduce your chances of developing complications. These medications, which include acyclovir (Zovirax), famciclovir (Famvir), and valacyclovir (Valtrex), work by blocking the virus's ability to reproduce. When there is less virus present, your immune system has a better chance of getting the reactivation under control. Be certain to reach out to your doctor quickly if you suspect you have shingles, because these drugs work best if they are started within 72 hours of the start of symptoms. Q. What is the best way to prevent shingles? A. The best way to avoid a painful case of shingles is to get vaccinated. The FDA approved the Shingrix vaccine in October 2017. A few years after Shingrix was approved, an older shingles vaccine called Zostavax was discontinued because it was much less effective. Shingrix is recommended for adults over age 50 and is given in a series of two injections, six months apart. Q. Is there anything I can do to help relieve shingles symptoms? A. The most bothersome symptoms associated with shingles are typically itching and pain related to the rash. There are a number of strategies that may help. For pain, try

Sleep disturbance and obstructive sleep apnea are associated with EDS. The association is thought to be caused by abnormalities in facial soft tissues. Repeated joint injuries can cause early-onset osteoarthritis and many other orthopedic conditions.