Understand the source comparison
Survodutide COA: Quality Metrics Comparison
HPLC Purity 95–98% ≥98.5% <95% or multiple peaks >10% Below 95%, impurities interfere with receptor studies Molecular Weight (MS) ±1 Da from expected ±0.5 Da from expected ±2 Da or multiple peaks Variance >2 Da suggests synthesis error or degradation Endotoxin
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- HPLC Purity
- 95–98%
- ≥98.5%
- <95% or multiple peaks >10%
- Below 95%, impurities interfere with receptor studies
- Molecular Weight (MS)
- ±1 Da from expected
- ±0.5 Da from expected
- ±2 Da or multiple peaks
- Variance >2 Da suggests synthesis error or degradation
- Endotoxin Level
- <5 EU/mg
- <1 EU/mg
- >10 EU/mg
- Above 5 EU/mg causes immune activation in cell/animal models
- Sterility (USP <71>)
- Pass (no growth 14 days)
- Not tested or fail
- Untested batches risk contaminating cultures and protocols
- Visual Appearance
- White to off-white powder
- White lyophilized powder
- Yellow, brown, or clumped
- Color indicates oxidation; clumping suggests moisture exposure
- Professional Assessment
- Accept if all parameters meet research-grade thresholds and HPLC chromatogram shows single dominant peak
- Pharmaceutical-grade required for clinical translation; research-grade sufficient for in vitro and preclinical work
- Reject batch if any parameter exceeds red flag threshold. Do not attempt to 'work around' quality failures
- Quality failures compound across experiments; one contaminated batch can invalidate months of data