Understand the source comparison
How to Use Peptides for Alopecia: Treatment Comparison
GHK-Cu (Copper Peptide) DHT receptor blockade + TGF-β upregulation Androgenetic alopecia (pattern baldness) Topical post-microneedling 2–3× weekly, 1% concentration Gold standard for miniaturised follicle reversal. Best evidence base for non-finasteride DHT mo
No winner is assigned.
This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.
- GHK-Cu (Copper Peptide)
- DHT receptor blockade + TGF-β upregulation
- Androgenetic alopecia (pattern baldness)
- Topical post-microneedling
- 2–3× weekly, 1% concentration
- Gold standard for miniaturised follicle reversal. Best evidence base for non-finasteride DHT modulation
- Thymosin Beta-4 (TB-500)
- Wnt/β-catenin stem cell activation
- Telogen effluvium, stress shedding
- Subcutaneous injection
- 2mg twice weekly
- Most effective regenerative peptide for dormant follicles. Requires systemic delivery, not topical
- BPC-157
- VEGF upregulation, microcirculation enhancement
- Chronic telogen, low scalp blood flow
- 500mcg daily or every other day
- Best for cases where follicle density is intact but growth phase shortened. Synergistic with TB-500
- KPV (Tripeptide)
- IL-17/TNF-alpha cytokine suppression
- Alopecia areata (autoimmune)
- Topical or subcutaneous
- 1–2mg daily, minimum 24 weeks
- Only peptide with documented immunomodulation in autoimmune alopecia. Slow onset but sustained remission
- Procyanidin B-2
- 5-alpha reductase competitive inhibition
- Androgenetic alopecia
- Topical (can combine with GHK-Cu)
- 1mg/ml 3× weekly
- Lower evidence than GHK-Cu but synergistic when combined. Avoid as monotherapy