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Peptide Therapy GuideClear peptide education

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DSIP Results After 1 Week: Sleep Architecture Comparison

Sleep Latency 22–28 minutes 12–16 minutes −8 to −12 minutes Peptides (1988) intranasal study, n=34 subjects Slow-Wave Sleep % 16–18% of TST 21–26% of TST +5 to +8% Sleep Medicine Reviews meta-analysis REM Latency 85–95 minutes 70–80 minutes −10 to −15 minutes

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  • Sleep Latency
  • 22–28 minutes
  • 12–16 minutes
  • −8 to −12 minutes
  • Peptides (1988) intranasal study, n=34 subjects
  • Slow-Wave Sleep %
  • 16–18% of TST
  • 21–26% of TST
  • +5 to +8%
  • Sleep Medicine Reviews meta-analysis
  • REM Latency
  • 85–95 minutes
  • 70–80 minutes
  • −10 to −15 minutes
  • Observed in stress-dysregulated populations only
  • Total Sleep Time
  • 6.8 hours average
  • 6.9 hours average
  • +6 minutes (not significant)
  • Most protocols show redistribution, not extension
  • Subjective Stress (10-point scale)
  • 7.2
  • 4.8
  • −2.4 points
  • Correlates with CRH suppression by day 6
  • Professional Assessment
  • Baseline indicates moderate stress-disrupted sleep with prolonged latency and reduced SWS. Typical of chronic HPA-axis activation. Week-one data shows recalibration toward parasympathetic dominance with architecture improvement but minimal duration change. Results align with hypothalamic modulation rather than direct sedation.