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Peptide Therapy GuideClear peptide education

Understand the source comparison

Cathelicidin Peptide LL-37 Versus Defensins

Cathelicidin peptide LL-37 and defensins are both host defence peptides involved in innate immune protection [3], [5]. LL-37 is the major human cathelicidin-derived peptide, while defensins are a separate family with different structures, expression patterns,

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This page preserves a source comparison for education. It does not add a rating, recommendation or clinical judgment.

  • Cathelicidin peptide LL-37 and defensins are both host defence peptides involved in innate immune protection [3], [5]. LL-37 is the major human cathelicidin-derived peptide, while defensins are a separate family with different structures, expression patterns, and antimicrobial properties [3].
  • The comparison is useful for biology, not for choosing a peptide. Neither family should be reduced to a simple “stronger” or “better” ranking without indication-specific, formulation-specific, and human outcome data.