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5Amino1MQ Same as 5-Amino-1MQ: Research Applications Comparison
The following table compares how both naming conventions appear across different research contexts and what each context requires for experimental validity. In vitro enzyme assays (recombinant NNMT) 5-Amino-1MQ (systematic) 0.1–10 µM IC50 confirmation via dose
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- The following table compares how both naming conventions appear across different research contexts and what each context requires for experimental validity.
- In vitro enzyme assays (recombinant NNMT)
- 5-Amino-1MQ (systematic)
- 0.1–10 µM
- IC50 confirmation via dose-response curve
- Both names appear interchangeably in published protocols. Verify purity ≥98% by HPLC regardless of format
- Cell culture metabolic studies (3T3-L1 adipocytes)
- 5Amino1MQ (shorthand)
- 5–50 µM
- Cytotoxicity screen (MTT or LDH assay)
- Shorthand format dominates lab notebooks but systematic format appears in publications. Functional equivalence confirmed
- Animal model studies (diet-induced obesity)
- 5-Amino-1MQ (IUPAC standard)
- 50–100 mg/kg oral dosing
- Pharmacokinetic profiling (Cmax, AUC)
- IUPAC format required for regulatory documentation. Same molecule, different naming compliance
- Supplier catalogs (research-grade)
- Both formats used
- N/A (lyophilized powder)
- Third-party CoA with mass spec confirmation
- Vendors use both interchangeably. Request CAS number (42464-96-0) verification to confirm identity
- Mitochondrial respiration studies (Seahorse assays)
- 5Amino1MQ (informal)
- 10–25 µM acute treatment
- Oxygen consumption rate (OCR) baseline stability
- Informal naming in methods sections does not indicate lower grade. Verify sterility and endotoxin testing