Guide library
Plain-language education with dates, authors and original source links where available.
Dive Brief: - Sanofi will advance an experimental inflammatory disease drug into Phase 2 clinical testing after its biotechnology company partner Kymera Therapeutics reported Wednesday what it described as enc…
Read guide →April 15, 2013 (Vol. 33, No. 8) RNAi research has capitalized on the ability to design and deliver small interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs) to knock down expression of target genes with s…
Read guide →Anthropic has released Claude Science, an AI workbench for scientists that consolidates fragmented research tools, including over 60 scientific databases and connectors pre-configured for genomics, proteomics,…
Read guide →Once labeled the “disease of kings” because of its association with consuming rich foods and alcohol, gout has emerged as a royal pain to a growing number of people. A 2024 study showed the prevalence of the m…
Read guide →Biomarker development is hardly coextensive with drug development, but in every developmental stage—from exploratory research to clinical trial to therapeutic application—there is significant overlap. As medic…
Read guide →A study headed by researchers at the Centre for Genomic Regulation (CRG) in Barcelona has provided for the first time evidence that a single drug, already licensed for medical use, can stabilize nearly all mut…
Read guide →A novel strategy developed by scientists at Rice University allows scientists to zoom in on tiny segments of proteins inside living cells, revealing localized environmental changes that could indicate the earl…
Read guide →Some drug treatments, particularly those that include high-dose protein-based therapeutics, are only available as an intravenous (IV) infusion. These protein therapeutics, which need to be delivered as dilute …
Read guide →Insmed (NASDAQ: INSM) is breathing easier since the FDA has approved the company’s Brinsupri™ (brensocatib 10 mg and 25 mg tablets) as the first drug authorized to treat non-cystic fibrosis bronchiectasis (NCF…
Read guide →Until recently, protein-protein interactions (PPIs) have been considered essentially “undruggable,” in part because of the presumed featurelessness of the interface between protein partners. But PPIs play a hu…
Read guide →Immunotherapies have already shown startling effectiveness against certain previously intractable cancers and a pair of scientists were awarded this year’s Nobel Prize for their research into immune mechanisms…
Read guide →A new method developed by researchers at the Centre for Genomic Regulation (CRG) in Barcelona has revealed the number of potential therapeutic targets on the surfaces of human proteins is much greater than pre…
Read guide →Proteins are the building blocks of all cells in our bodies and in all living creatures of all kingdoms. They play a role in keeping our cells and bodies functioning. Recent studies have demonstrated that prot…
Read guide →Synthetic biology is among the most exciting emerging technologies. By taking an engineering approach to living systems, synbio—as synthetic biology is often called—aims to design and build new biological prod…
Read guide →Olezarsen reduces triglycerides, cutting pancreatitis risk by 85% Key takeaways: - Monthly olezarsen is the first treatment to significantly reduce acute pancreatitis events along with triglyceride levels. - T…
Read guide →What Is Mitomycin and How Does It Work? Mitomycin is a prescription medication used in combination with other anti-cancer drugs to treat stomach and pancreas cancer. Mitomycin is available under the following …
Read guide →Description for Lutathera LUTATHERA (lutetium Lu 177 dotatate) is a radiolabeled somatostatin analog. The drug substance lutetium Lu 177 dotatate is a cyclic peptide linked with the covalently bound chelator 1…
Read guide →July 1, 2005 (Vol. 25, No. 13) Engineering and Expressing Novel Protein Therapeutics Driven by technology, protein and peptide drug exploration has been fed by the success of the human genome project, striking…
Read guide →Company also launched antidiabetic Galvus in China. China’s drug regulator cleared Novartis’ Lucentis® (ranibizumab) as a treatment for wet age-related macular degeneration. Novartis also confirmed the Chinese…
Read guide →Studies show that MIPs act as efficient nucleants for hard to crystallize molecules. Scientists claim molecularly imprinted polymers (MIPs) can be used as effective nucleants for the formation of large single …
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