Vanicream Daily Facial Moisturizer Versus Skinfix Triple-Lipid Peptide Lotion

Vanicream Daily Facial Moisturizer Versus Skinfix Triple-Lipid Peptide Lotion

This barrier-repair moisturizer is formulated around Squalane and Hyaluronic Acid to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Caprylic/Capric Triglyceride and Jojoba Oil/Macadamia Seed Oil Esters to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Squalane

Glycerin

Pentylene Glycol

Polyglyceryl-2 Stearate

Glyceryl Stearate

Stearyl Alcohol

Hyaluronic Acid

Ceramide EOP

Ceramide Ng

Ceramide NP

Ceramide As

Ceramide AP

Carnosine

Hydrogenated Lecithin

Phytosterols

Caprylyl Glycol

Polyacrylate Crosspolymer-11

1,2-Hexanediol

Water, Squalane, Glycerin, Pentylene Glycol, Polyglyceryl-2 Stearate, Glyceryl Stearate, Stearyl Alcohol, Hyaluronic Acid, Ceramide EOP, Ceramide Ng, Ceramide NP, Ceramide As, Ceramide AP, Carnosine, Hydrogenated Lecithin, Phytosterols, Caprylyl Glycol, Polyacrylate Crosspolymer-11, 1,2-Hexanediol

Dicaprylyl Carbonate

Caprylic/Capric Triglyceride

Propanediol

Caprylyl Caprylate/Caprate

Jojoba Oil/Macadamia Seed Oil Esters

Behenyl Alcohol

Butyrospermum Parkii Butter

Lecithin

Nylon-11

Dicaprylyl Ether

Sodium Hyaluronate

Oryza Sativa Bran Extract

Glycine Soja Seed Extract

Squalene

Hydrolyzed Rice Protein

Hydrogenated Vegetable Oil

Glycine Soja Sterols

Phytosteryl Canola Glycerides

Chondrus Crispus Extract

Phytosteryl Macadamiate

Aloe Barbadensis Leaf Juice

Rosmarinus Officinalis Leaf Extract

Helianthus Annuus Extract

Ethylhexylglycerin

Tocopherol

Dilinoleic Acid/Propanediol Copolymer

Trisodium Ethylenediamine Disuccinate

Gluconolactone

Sodium Benzoate

Xanthan Gum

Phenoxyethanol

Potassium Sorbate

Citric Acid

Water, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Behenyl Alcohol, Glyceryl Stearate, Butyrospermum Parkii Butter, Lecithin, Stearyl Alcohol, Nylon-11, Dicaprylyl Ether, Sodium Hyaluronate, Oryza Sativa Bran Extract, Glycine Soja Seed Extract, Squalene, Hydrolyzed Rice Protein, Hydrogenated Vegetable Oil, Glycine Soja Sterols, Phytosteryl Canola Glycerides, Chondrus Crispus Extract, Phytosteryl Macadamiate, Phytosterols, Aloe Barbadensis Leaf Juice, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Extract, Ethylhexylglycerin, Tocopherol, Dilinoleic Acid/Propanediol Copolymer, Pentylene Glycol, Trisodium Ethylenediamine Disuccinate, Gluconolactone, Sodium Benzoate, Xanthan Gum, Phenoxyethanol, Potassium Sorbate, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phytosterols are plant-derived sterols (you can think of them as the plant world's version of cholesterol). In cosmetics, this ingredient is usually sourced from soybean, rice bran, shea, sunflower, and other seed oils.

The main actors in this group are β-sitosterol, campesterol, and stigmasterol (the CIR covers 27 phytosterols).

They work by fitting perfectly into your stratum corneum's lipid matrix since they're structurally similar to cholesterol. Here, they reinforce your skin's barrier.

One small in vivo human study showed topical soybean phytosterols sped up barrier recovery within three days on tape-stripped skin.

Broader research credits them with:

Formulation use typically sit under 5%.

Testing in soy-allergic subjects found no sensitization signals, but be sure to patch test if you are unsure or have existing allergies.

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.

Emollients help soothe and hydrate the skin by trapping moisture.

Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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