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Skinfix Triple-Lipid Peptide Lotion Versus Tula Skincare 24-7 Moisture Hydrating Day & Night Cream

Skinfix Triple-Lipid Peptide Lotion Versus Tula Skincare 24-7 Moisture Hydrating Day & Night Cream This barrier-repair moisturizer is formulated around Caprylic/Capric Triglyceride and Jojoba Oil/Macadamia Seed Oil Esters to strengthen the skin barrier and hyd

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Skinfix Triple-Lipid Peptide Lotion Versus Tula Skincare 24-7 Moisture Hydrating Day & Night Cream

This barrier-repair moisturizer is formulated around Caprylic/Capric Triglyceride and Jojoba Oil/Macadamia Seed Oil Esters to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Squalane and Bifida Ferment Lysate to strengthen the skin barrier and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dicaprylyl Carbonate

Caprylic/Capric Triglyceride

Glycerin

Propanediol

Caprylyl Caprylate/Caprate

Jojoba Oil/Macadamia Seed Oil Esters

Behenyl Alcohol

Glyceryl Stearate

Butyrospermum Parkii Butter

Lecithin

Stearyl Alcohol

Nylon-11

Dicaprylyl Ether

Sodium Hyaluronate

Oryza Sativa Bran Extract

Glycine Soja Seed Extract

Squalene

Hydrolyzed Rice Protein

Hydrogenated Vegetable Oil

Glycine Soja Sterols

Phytosteryl Canola Glycerides

Chondrus Crispus Extract

Phytosteryl Macadamiate

Phytosterols

Aloe Barbadensis Leaf Juice

Rosmarinus Officinalis Leaf Extract

Helianthus Annuus Extract

Ethylhexylglycerin

Tocopherol

Dilinoleic Acid/Propanediol Copolymer

Pentylene Glycol

Trisodium Ethylenediamine Disuccinate

Gluconolactone

Sodium Benzoate

Xanthan Gum

Phenoxyethanol

Potassium Sorbate

Citric Acid

Water, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Glycerin, Propanediol, Caprylyl Caprylate/Caprate, Jojoba Oil/Macadamia Seed Oil Esters, Behenyl Alcohol, Glyceryl Stearate, Butyrospermum Parkii Butter, Lecithin, Stearyl Alcohol, Nylon-11, Dicaprylyl Ether, Sodium Hyaluronate, Oryza Sativa Bran Extract, Glycine Soja Seed Extract, Squalene, Hydrolyzed Rice Protein, Hydrogenated Vegetable Oil, Glycine Soja Sterols, Phytosteryl Canola Glycerides, Chondrus Crispus Extract, Phytosteryl Macadamiate, Phytosterols, Aloe Barbadensis Leaf Juice, Rosmarinus Officinalis Leaf Extract, Helianthus Annuus Extract, Ethylhexylglycerin, Tocopherol, Dilinoleic Acid/Propanediol Copolymer, Pentylene Glycol, Trisodium Ethylenediamine Disuccinate, Gluconolactone, Sodium Benzoate, Xanthan Gum, Phenoxyethanol, Potassium Sorbate, Citric Acid

Butylene Glycol

Ethylhexyl Palmitate

Squalane

Cetyl Alcohol

Dimethicone

PEG-100 Stearate

Bifida Ferment Lysate

Lactose

Lactis Proteinum

Yogurt Extract

Cichorium Intybus Root Extract

Vaccinium Angustifolium Fruit Extract

Vegetable Oil

Camelina Sativa Seed Oil

Camellia Sinensis Leaf Extract

Curcuma Longa Root Extract

Tocopheryl Acetate

Ascorbyl Palmitate

Carthamus Tinctorius Seed Oil

Olea Europaea Fruit Oil

Pyrus Malus Fruit Extract

Citrullus Lanatus Fruit Extract

Lens Esculenta Fruit Extract

Sodium Lactate

Sodium PCA

Carbomer

Sodium Hydroxide

Caprylyl Glycol

Bulnesia Sarmientoi Wood Oil

Citrus Limon Fruit Oil

Citrus Aurantium Dulcis Oil

Juniperus Mexicana Oil

Cananga Odorata Flower Oil

Disodium EDTA

Sorbic Acid

Phenethyl Alcohol

Parfum

Alpha-Isomethyl Ionone

Butylphenyl Methylpropional

Linalool

Hexyl Cinnamal

Water, Butylene Glycol, Ethylhexyl Palmitate, Squalane, Glycerin, Cetyl Alcohol, Caprylic/Capric Triglyceride, Dimethicone, Hydrogenated Vegetable Oil, Glyceryl Stearate, PEG-100 Stearate, Bifida Ferment Lysate, Lactose, Lactis Proteinum, Yogurt Extract, Hydrolyzed Rice Protein, Cichorium Intybus Root Extract, Vaccinium Angustifolium Fruit Extract, Vegetable Oil, Camelina Sativa Seed Oil, Camellia Sinensis Leaf Extract, Curcuma Longa Root Extract, Tocopheryl Acetate, Ascorbyl Palmitate, Carthamus Tinctorius Seed Oil, Olea Europaea Fruit Oil, Pyrus Malus Fruit Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Sodium Lactate, Sodium PCA, Carbomer, Sodium Hydroxide, Pentylene Glycol, Caprylyl Glycol, Bulnesia Sarmientoi Wood Oil, Citrus Limon Fruit Oil, Citrus Aurantium Dulcis Oil, Juniperus Mexicana Oil, Cananga Odorata Flower Oil, Ethylhexylglycerin, Stearyl Alcohol, Disodium EDTA, Citric Acid, Sorbic Acid, Phenethyl Alcohol, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol, Parfum, Alpha-Isomethyl Ionone, Butylphenyl Methylpropional, Linalool, Hexyl Cinnamal

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss.

Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid.

In practice, that translates to a long shelf life and a consistently elegant skin feel.

While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns.

Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source.

This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out.

This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%.

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Hydrogenated Vegetable Oil is created by adding hydrogen to vegetable oil in order to give it more stability. This process also raises the melting point of vegetable oil. In cosmetics, it is an emollient.

Emollients help soothe and soften the skin. They do this by creating a protective film on your skin. This barrier helps trap moisture and keeps your skin hydrated. Emollients may be effective at treating dry or itchy skin.

The term "Hydrogenated Vegetable Oil" is an umbrella term and can refer to a variety of vegetable oils and blends of: sunflower oil, soybean oil, olive oil, coconut oil, palm oil, and more.

Due to the differences in vegetables, the benefits may vary.

Hydrolyzed Rice Protein is protein extracted from rice. This ingredient is rich in antioxidants and peptides.

Studies show this ingredient may help with blocking the melanin creation process when skin is exposed to UV.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.

This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.

Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.

You'll often find this ingredient used with other preservatives.

Sodium Benzoate is a preservative. It's used in both cosmetic and food products to inhibit the growth of mold and bacteria. It is typically produced synthetically.

Both the US FDA and EU Health Committee have approved the use of sodium benzoate. In the US, levels of 0.1% (of the total product) are allowed.

Sodium benzoate works as a preservative by inhibiting the growth of bacteria inside of cells. It prevents the cell from fermenting a type of sugar using an enzyme called phosphofructokinase.

It is the salt of benzoic acid. Foods containing sodium benzoate include soda, salad dressings, condiments, fruit juices, wines, and snack foods.

Studies for using ascorbic acid and sodium benzoate in cosmetics are lacking, especially in skincare routines with multiple steps.

We always recommend speaking with a professional, such as a dermatologist, if you have any concerns.

Stearyl Alcohol is a type of fatty alcohol from stearic acid. It is a white, waxy compound used to emulsify ingredients used as an emollient or to thicken a product.

Emollients help soothe and hydrate the skin by trapping moisture.

Fatty alcohols are usually derived from natural fats and oils and therefore do not have the same drying or irritating effect as solvent (ethanol) alcohols.

The FDA allows products labeled "alcohol-free" to have fatty alcohols.

This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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