Theramid Derma-Peptides 35% Versus The Ordinary GF 15% Solution

Theramid Derma-Peptides 35% Versus The Ordinary GF 15% Solution

This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture.

This anti-aging serum is formulated around Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 and Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 to soften the look of wrinkles and fade the look of dark spots.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Glycerin

Propanediol

Caprylic/Capric Triglyceride

Butylene Glycol

Dodecane

C15-19 Alkane

Ethyl Macadamiate

Silica

Glycine Soja Seed Extract

Sodium Hyaluronate

Acetyl Hexapeptide-1

N-Prolyl Palmitoyl Tripeptide-56 Acetate

Acetyl Tetrapeptide-2

Palmitoyl Tripeptide-38

Palmitoyl Tripeptide-1

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-11

Sh-Polypeptide-9

Palmitoyl Dipeptide-10

Palmitoyl Tetrapeptide-7

Nonapeptide-1

Palmitoyl Tetrapeptide-72 Amide

Acetyl Glutamine

Bacillus/Folic Acid Ferment Filtrate Extract

Tocopherol

Polyacrylate-13

Pullulan

Polyisobutene

Pentylene Glycol

Polysorbate 20

1,2-Hexanediol

Lecithin

Sorbitan Isostearate

Carbomer

Sclerotium Gum

Xanthan Gum

Sodium Lactate

Cetyl Alcohol

Hydroxypropyl Cyclodextrin

Malic Acid

Dextran

Caprylyl Glycol

Ethylhexylglycerin

Phenoxyethanol

Water, Glycerin, Propanediol, Caprylic/Capric Triglyceride, Butylene Glycol, Dodecane, C15-19 Alkane, Ethyl Macadamiate, Silica, Glycine Soja Seed Extract, Sodium Hyaluronate, Acetyl Hexapeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Acetyl Tetrapeptide-2, Palmitoyl Tripeptide-38, Palmitoyl Tripeptide-1, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Palmitoyl Dipeptide-10, Palmitoyl Tetrapeptide-7, Nonapeptide-1, Palmitoyl Tetrapeptide-72 Amide, Acetyl Glutamine, Bacillus/Folic Acid Ferment Filtrate Extract, Tocopherol, Polyacrylate-13, Pullulan, Polyisobutene, Pentylene Glycol, Polysorbate 20, 1,2-Hexanediol, Lecithin, Sorbitan Isostearate, Carbomer, Sclerotium Gum, Xanthan Gum, Sodium Lactate, Cetyl Alcohol, Hydroxypropyl Cyclodextrin, Malic Acid, Dextran, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76

Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2

Trisodium Ethylenediamine Disuccinate

Citric Acid

Sodium Citrate

Chlorphenesin

Water, Butylene Glycol, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2, Sclerotium Gum, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Sodium Citrate, Phenoxyethanol, Chlorphenesin

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sclerotium Gum is a natural sugar-based fiber made by fermenting a fungus called Sclerotium rolfsii. It's often used as the plant-friendly alternative for synthetic thickeners like carbomer.

In skincare, it works as a thickener, gel former, and stabilizer that keeps heavy ingredients suspended so a product does not separate.

It is non-ionic and forms a triple helix in solution. This is just a fancy way of saying it builds a smooth, cushiony, and non-sticky gel that feels silkier than many other gums.

Another perk of this ingredient is that it is very sturdy and holds up across a wide pH range (~2-11). It's also good at resisting heat and hydrolysis.

Since it holds water at the skin surface, it can provide some light hydration as well.

Typical use levels are around 0.25-2%; formulators usually use 0.2-0.5% to thicken lotions and up to 2% for a firmer gel base.

This ingredient has been found safe in cosmetics with no meaningful evidence of skin sensitization.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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