T1 peptide

Product Information

• Product Name

  T1 peptide

• Documents
• Sequence Shortening

  MSRPACPNDKYE

• Sequence

  H-Met-Ser-Arg-Pro-Ala-Cys-Pro-Asn-Asp-Lys-Tyr-Glu-OH

• Length (aa)

  12

• Peptide Purity (HPLC)

  95.9%

• Molecular Formula

  C58H91N17O20S2

• Molecular Weight

  1410.6

• Source

  Synthetic

• Form

  Powder

• Description

  This peptide is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. It has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor.MSRPACPNDKYE has served as model peptide in protein modification and

• Storage Guidelines

  Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides

• References
  • J.Doorbar and G.Winter, J. Mol. Biol., 244, 361 (1994)
  • H.Schafberg et al., Br. J. Cancer, 76, 1592 (1997)
  • R.Kaufmann et al., NeuroReport, 9, 709 (1998)
  • H.Y. Tang and D.W.Speicher, Anal. Biochem., 334, 48 (2004)
  • M.C.Sun et al., J. Sep. Sci., 31, 538 (2008)
• About TFA salt

  Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

  Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

  Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

  In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

• Molar Concentration Calculator

• Dilution Calculator

• Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Peptide Property

• Analysed Sequence:H-MSRPACPNDKYE-OH
• Chemical Formula:C58H91N17O20S2
• Sequence length:12
• Extinction coefficient:1280 M-1cm-1
• GRAVY:-1.5
• Mw average:1410.57
• Theoretical pI:6.34
• Data Source:Peptide Property Calculator

GRAVY = grand average of hydropathy

X: Hydrophobic uncharged residues, like F I L M V W A and P

X: Basic residues, like R K H

X: Acidic residues, like D E

X: Polar uncharged residues, like G S T C N Q and Y

• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.