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Sungboon Editor Silk Peptide Intensive Lifting Ampoule Versus BOH Bio Heal Probioderm 3D Lifting Ampoule

Sungboon Editor Silk Peptide Intensive Lifting Ampoule Versus BOH Bio Heal Probioderm 3D Lifting Ampoule This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles. This anti-aging ampoule is formulated around Lactobaci

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Sungboon Editor Silk Peptide Intensive Lifting Ampoule Versus BOH Bio Heal Probioderm 3D Lifting Ampoule

This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles.

This anti-aging ampoule is formulated around Lactobacillus Ferment Lysate and Adenosine to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Butylene Glycol

Glycerin

Methylpropanediol

1,2-Hexanediol

Niacinamide

Carbomer

Tromethamine

PPG-13-Decyltetradeceth-24

Hydroxyethylcellulose

Silk Extract

Adenosine

Iron Powder

Agar

Ethylhexylglycerin

Disodium EDTA

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Synthetic Fluorphlogopite

Betaine

Panthenol

Hydrolyzed Elastin

Titanium Dioxide

CI 77491

Mica

Gellan Gum

Hydrolyzed Collagen

Centella Asiatica Extract

Propanediol

Magnesium Ascorbyl Phosphate

Polygonum Fagopyrum Seed Extract

Lecithin

Acetyl Glutamine

Phenoxyethanol

Artemisia Vulgaris Extract

Sodium Hyaluronate

Caprylyl Glycol

Tin Oxide

Gold

Squalane

Hydrogenated Polyisobutene

Benzyl Glycol

Sh-Oligopeptide-1

Sh-Polypeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-11

Sh-Polypeptide-9

Bacillus

Hydrolyzed Glycosaminoglycans

Collagen

Tocopherol

Sodium Hyaluronate Crosspolymer

Caffeoyl Hexapeptide-65

Hydrolyzed Hyaluronic Acid

Sh-Decapeptide-7

Sh-Octapeptide-4

Sh-Oligopeptide-9

Sh-Pentapeptide-19

Hydroxypropyltrimonium Hyaluronate

Palmitoyl Pentapeptide-4

Acetyl Hexapeptide-8

Copper Tripeptide-1

Hyaluronic Acid

Ulmus Davidiana Root Extract

Sodium Acetylated Hyaluronate

Water, Butylene Glycol, Glycerin, Methylpropanediol, 1,2-Hexanediol, Niacinamide, Carbomer, Tromethamine, PPG-13-Decyltetradeceth-24, Hydroxyethylcellulose, Silk Extract, Adenosine, Iron Powder, Agar, Ethylhexylglycerin, Disodium EDTA, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Synthetic Fluorphlogopite, Betaine, Panthenol, Hydrolyzed Elastin, Titanium Dioxide, CI 77491, Mica, Gellan Gum, Hydrolyzed Collagen, Centella Asiatica Extract, Propanediol, Magnesium Ascorbyl Phosphate, Polygonum Fagopyrum Seed Extract, Lecithin, Acetyl Glutamine, Phenoxyethanol, Artemisia Vulgaris Extract, Sodium Hyaluronate, Caprylyl Glycol, Tin Oxide, Gold, Squalane, Hydrogenated Polyisobutene, Benzyl Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-11, Sh-Polypeptide-9, Bacillus, Hydrolyzed Glycosaminoglycans, Collagen, Tocopherol, Sodium Hyaluronate Crosspolymer, Caffeoyl Hexapeptide-65, Hydrolyzed Hyaluronic Acid, Sh-Decapeptide-7, Sh-Octapeptide-4, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Hydroxypropyltrimonium Hyaluronate, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hyaluronic Acid, Ulmus Davidiana Root Extract, Sodium Acetylated Hyaluronate

Lactobacillus Ferment Lysate

Isopentyldiol

Caprylic/Capric Triglyceride

Polyglycerin-3

Cetyl Ethylhexanoate

Lactobacillus Ferment

Fructooligosaccharides

Fructan

Inulin

Beta-Glucan

Saponins

Soluble Proteoglycan

Nonapeptide-1

Acetyl Tetrapeptide-9

Acetyl Tetrapeptide-5

Acetyl Hexapeptide-1

Palmitoyl Tripeptide-8

Dipeptide Diaminobutyroyl Benzylamide Diacetate

Tripeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Palmitoyl Tripeptide-5

Palmitoyl Hexapeptide-12

Pentapeptide-3

Hexapeptide-9

Oligopeptide-2

Glyceryl Citrate/Lactate/Linoleate/Oleate

Malt Extract

Dioscorea Japonica Root Extract

Elaeis Guineensis Oil

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Polyacrylate Crosspolymer-6

Maltodextrin

Glyceryl Polymethacrylate

Sodium Polyacrylate

Sorbitan Isostearate

Algin

Biosaccharide Gum-4

Cyanocobalamin

Cetearyl Glucoside

Cetearyl Alcohol

Sodium Stearoyl Glutamate

Xanthan Gum

Hydrolyzed Corn Starch

Sucrose

Sodium Phosphate

Mineral Salts

Dextran

Disodium Phosphate

Parfum

Lactobacillus Ferment Lysate, Water, Isopentyldiol, Glycerin, Caprylic/Capric Triglyceride, Polyglycerin-3, 1,2-Hexanediol, Cetyl Ethylhexanoate, Lactobacillus Ferment, Fructooligosaccharides, Fructan, Inulin, Panthenol, Betaine, Beta-Glucan, Adenosine, Saponins, Soluble Proteoglycan, Nonapeptide-1, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-5, Acetyl Hexapeptide-1, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-8, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Pentapeptide-3, Hexapeptide-9, Oligopeptide-2, Glyceryl Citrate/Lactate/Linoleate/Oleate, Malt Extract, Dioscorea Japonica Root Extract, Elaeis Guineensis Oil, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyacrylate Crosspolymer-6, Maltodextrin, Ethylhexylglycerin, Propanediol, Glyceryl Polymethacrylate, Sodium Polyacrylate, Sorbitan Isostearate, Algin, Biosaccharide Gum-4, Cyanocobalamin, Cetearyl Glucoside, Cetearyl Alcohol, Butylene Glycol, Sodium Stearoyl Glutamate, Tocopherol, Xanthan Gum, Hydrolyzed Corn Starch, Sucrose, Sodium Phosphate, Caprylyl Glycol, Mineral Salts, Dextran, Disodium Phosphate, Parfum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative".

It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time.

The comparison to Botox does have limits because the molecule is water-loving and relatively large.

Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles.

So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging.

A 12 week human study of a multi-ingredient regimen containing this ingredient saw:

While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone).

Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations.

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Betaine is a humectant. Like hyaluronic acid, it helps attract and retain moisture in the skin. It’s known for being gentle and for helping the skin maintain balanced hydration.

Betaine is mainly used to improve hydration and support calmer skin. It helps skin cells regulate water balance because it functions as an osmolyte.

Some studies suggest betaine may support making skin tone more even.

Fun fact: Betaine naturally exists in the skin and the body. In cosmetic products, it can be either plant-derived (most commonly from sugar beets) or synthetically produced for consistency and stability.

Betaine is also known as trimethylglycine.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Copper Tripeptide-1 (GHK-Cu) is a skin repairing ingredient known for its ability to boost collagen, improve firmness, and support skin regeneration.

It is a complex made up of a naturally occurring peptide (glycine-histidine-lysine) and copper, an essential trace element.

While studying wound healing, researchers noticed GHK-Cu stimulated hair follicle enlargement and growth by keeping hair in its active growth phase longer. This has made it a promising ingredient for hair regrowth treatments.

Some people have reported increased facial hair. While GHK-Cu can make your hair follicles bigger, it usually doesn’t turn soft, barely-visible facial hairs into thick, dark ones.

Anecdotal reports suggest that overusing copper peptides might lead to premature aging due to excess free copper or enzyme imbalances. This claim isn’t backed by large-scale studies.

Unfortunately, there are limited human studies for this ingredient. While early results are promising, many studies are either small, in-vitro, or not rigorously controlled.

For example, there is a 1998 study that explored the effects of copper tripeptide, vitamin C, tretinoin, and melatonin on skin repair and collagen synthesis.

After one month, increased procollagen production was seen in 7 out of 10 participants using copper tripeptide (more than those using vitamin C, melatonin, or tretinoin.

While the study was exploratory, it offers early evidence that copper tripeptide may support collagen production. Larger, well-designed trials are still needed to confirm its potential and understand individual responses.

Read more about other common types of peptides here:

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

You might know this ingredient as Matrixyl. It is a synthetic peptide made up of five amino acids attached to a palmitic acid, a fatty acid that helps it absorb into skin more easily.

As a signal peptide, Matrixyl acts like a little messenger. Once it reaches your skin cells, it tells them to ramp up production of collagen, elastin, and other proteins that keep skin looking firm and smooth.

A 12 week clinical study found that a moisturizer containing just 3 ppm of Matrixyl led to a significant improvement in fine-lines and wrinkles. Another study showed an 18% reduction in wrinkle depth, 37% reduction in wrinkle thickness, and a 21% improvement in skin firmness after just 28 days of twice-daily use.

The coolest part is that it works at incredibly low concentrations (like 0.0003%) and it plays well with other actives.

The CIR (Cosmetic Ingredient Review) panel found it to be non-sensitizing across multiple tests and human patch tests also showed no irritation or sensitization.

Fun fact: Matrixyl was originally developed by French company Sederma and Procter & Gamble.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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