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VT Cosmetics PDRN Glow Ampoule Versus Sungboon Editor Silk Peptide Intensive Lifting Ampoule

VT Cosmetics PDRN Glow Ampoule Versus Sungboon Editor Silk Peptide Intensive Lifting Ampoule This brightening ampoule is formulated around Niacinamide and Sodium DNA to brighten dull-looking skin and soften the look of wrinkles. This anti-aging serum is formul

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

VT Cosmetics PDRN Glow Ampoule Versus Sungboon Editor Silk Peptide Intensive Lifting Ampoule

This brightening ampoule is formulated around Niacinamide and Sodium DNA to brighten dull-looking skin and soften the look of wrinkles.

This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

No concerns

Ingredients Side-by-side

Water

Methylpropanediol

Limnanthes Alba Seed Oil

Niacinamide

Butylene Glycol

Glycerin

Triethylhexanoin

Polyglycerin-3

Dipropylene Glycol

1,2-Hexanediol

Hydroxyacetophenone

Sodium Citrate

Polyglyceryl-10 Myristate

Ethylhexylglycerin

Citric Acid

Adenosine

Sodium Phytate

Panthenol

Allantoin

Disodium EDTA

Squalane

Caprylic/Capric Triglyceride

Ceramide NP

Adansonia Digitata Seed Oil

Hydrogenated Lecithin

Polyglucuronic Acid

Tocopherol

Sodium Hyaluronate

Ceramide As

Ceramide Ns

Ceramide AP

Ceramide EOP

Panax Ginseng Root Extract

Sodium DNA

Water, Methylpropanediol, Limnanthes Alba Seed Oil, Niacinamide, Butylene Glycol, Glycerin, Triethylhexanoin, Polyglycerin-3, Dipropylene Glycol, 1,2-Hexanediol, Hydroxyacetophenone, Sodium Citrate, Polyglyceryl-10 Myristate, Ethylhexylglycerin, Citric Acid, Adenosine, Sodium Phytate, Panthenol, Allantoin, Disodium EDTA, Squalane, Caprylic/Capric Triglyceride, Ceramide NP, Adansonia Digitata Seed Oil, Hydrogenated Lecithin, Polyglucuronic Acid, Tocopherol, Sodium Hyaluronate, Ceramide As, Ceramide Ns, Ceramide AP, Ceramide EOP, Panax Ginseng Root Extract, Sodium DNA

Carbomer

Tromethamine

PPG-13-Decyltetradeceth-24

Hydroxyethylcellulose

Silk Extract

Iron Powder

Agar

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Synthetic Fluorphlogopite

Betaine

Hydrolyzed Elastin

Titanium Dioxide

CI 77491

Mica

Gellan Gum

Hydrolyzed Collagen

Centella Asiatica Extract

Propanediol

Magnesium Ascorbyl Phosphate

Polygonum Fagopyrum Seed Extract

Lecithin

Acetyl Glutamine

Phenoxyethanol

Artemisia Vulgaris Extract

Caprylyl Glycol

Tin Oxide

Gold

Hydrogenated Polyisobutene

Benzyl Glycol

Sh-Oligopeptide-1

Sh-Polypeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-11

Sh-Polypeptide-9

Bacillus

Hydrolyzed Glycosaminoglycans

Collagen

Sodium Hyaluronate Crosspolymer

Caffeoyl Hexapeptide-65

Hydrolyzed Hyaluronic Acid

Sh-Decapeptide-7

Sh-Octapeptide-4

Sh-Oligopeptide-9

Sh-Pentapeptide-19

Hydroxypropyltrimonium Hyaluronate

Palmitoyl Pentapeptide-4

Acetyl Hexapeptide-8

Copper Tripeptide-1

Hyaluronic Acid

Ulmus Davidiana Root Extract

Sodium Acetylated Hyaluronate

Water, Butylene Glycol, Glycerin, Methylpropanediol, 1,2-Hexanediol, Niacinamide, Carbomer, Tromethamine, PPG-13-Decyltetradeceth-24, Hydroxyethylcellulose, Silk Extract, Adenosine, Iron Powder, Agar, Ethylhexylglycerin, Disodium EDTA, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Synthetic Fluorphlogopite, Betaine, Panthenol, Hydrolyzed Elastin, Titanium Dioxide, CI 77491, Mica, Gellan Gum, Hydrolyzed Collagen, Centella Asiatica Extract, Propanediol, Magnesium Ascorbyl Phosphate, Polygonum Fagopyrum Seed Extract, Lecithin, Acetyl Glutamine, Phenoxyethanol, Artemisia Vulgaris Extract, Sodium Hyaluronate, Caprylyl Glycol, Tin Oxide, Gold, Squalane, Hydrogenated Polyisobutene, Benzyl Glycol, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-11, Sh-Polypeptide-9, Bacillus, Hydrolyzed Glycosaminoglycans, Collagen, Tocopherol, Sodium Hyaluronate Crosspolymer, Caffeoyl Hexapeptide-65, Hydrolyzed Hyaluronic Acid, Sh-Decapeptide-7, Sh-Octapeptide-4, Sh-Oligopeptide-9, Sh-Pentapeptide-19, Hydroxypropyltrimonium Hyaluronate, Palmitoyl Pentapeptide-4, Acetyl Hexapeptide-8, Copper Tripeptide-1, Hyaluronic Acid, Ulmus Davidiana Root Extract, Sodium Acetylated Hyaluronate

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Methylpropanediol is a synthetic solvent and humectant.

As a solvent, it helps dissolve other ingredients, helping to evenly distribute ingredients throughout the product. This ingredient has also been shown to have antimicrobial properties which makes it a preservative booster.

Methylpropanediol is able to add a bit of moisture to the skin. It also helps other ingredients be better absorbed into the skin, such as salicylic acid.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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