Skintific 5X Ceramide Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

Skintific 5X Ceramide Serum Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

This barrier-repair serum is formulated around Bifida Ferment Lysate and Niacinamide to strengthen the skin barrier and calm redness.

This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Methylpropanediol

Bifida Ferment Lysate

Glycerin

Niacinamide

Dimethicone

Pentylene Glycol

Dipropylene Glycol

Glycereth-26

Centella Asiatica Extract

Propylene Glycol

Maris Aqua

Ceramide NP

Panthenol

Ceramide Ns

Ceramide Ng

Ceramide As

Ceramide EOP

Ceramide AP

Sodium Hyaluronate

PEG-60 Hydrogenated Castor Oil

Hydroxyethyl Urea

Bis-PEG-18 Methyl Ether Dimethyl Silane

4-T-Butylcyclohexanol

Ubiquinone

PEG-10 Dimethicone

Isononyl Isononanoate

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Bisabolol

Ectoin

Ammonium Polyacryloyldimethyl Taurate

Tocopherol

Lactobacillus/Soymilk Ferment Filtrate

Hydrogenated Lecithin

Hamamelis Virginiana Extract

Zingiber Officinale Root Extract

1,2-Hexanediol

Polyacrylate Crosspolymer-6

C12-20 Alkyl Glucoside

O-Cymen-5-Ol

Hydroxyacetophenone

Dimethiconol

Sodium Polyacrylate

Glucose

Water, Methylpropanediol, Bifida Ferment Lysate, Glycerin, Niacinamide, Dimethicone, Pentylene Glycol, Dipropylene Glycol, Glycereth-26, Centella Asiatica Extract, Propylene Glycol, Maris Aqua, Ceramide NP, Panthenol, Ceramide Ns, Ceramide Ng, Ceramide As, Ceramide EOP, Ceramide AP, Sodium Hyaluronate, PEG-60 Hydrogenated Castor Oil, Hydroxyethyl Urea, Bis-PEG-18 Methyl Ether Dimethyl Silane, 4-T-Butylcyclohexanol, Ubiquinone, PEG-10 Dimethicone, Isononyl Isononanoate, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Bisabolol, Ectoin, Ammonium Polyacryloyldimethyl Taurate, Tocopherol, Lactobacillus/Soymilk Ferment Filtrate, Hydrogenated Lecithin, Hamamelis Virginiana Extract, Zingiber Officinale Root Extract, 1,2-Hexanediol, Polyacrylate Crosspolymer-6, C12-20 Alkyl Glucoside, O-Cymen-5-Ol, Hydroxyacetophenone, Dimethiconol, Sodium Polyacrylate, Glucose

PEG-8

Propanediol

Methyl Gluceth-20

PEG-75

Butylene Glycol

Adansonia Digitata Seed Extract

Tripeptide-32

Faex Extract

Lactobacillus Ferment

Cola Acuminata Seed Extract

Anthemis Nobilis Flower Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Sodium Rna

Squalane

Oleth-3 Phosphate

Caprylyl Glycol

Oleth-3

Oleth-5

Choleth-24

Jojoba Wax PEG-120 Esters

Ceteth-24

Tocopheryl Acetate

Carbomer

Triethanolamine

Tetrasodium EDTA

BHT

Xanthan Gum

Potassium Sorbate

Disodium EDTA

Phenoxyethanol

CI 14700

CI 19140

Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Bifida Ferment Lysate is a postbiotic ingredient made by fermenting Bifidobacterium to extract a nutrient-rich mix of peptides, amino acids, vitamins, organic acids, and polysaccharides.

These components are basically the building blocks that your skin already uses to stay hydrated, repair itself, and maintain its barrier. That's why this ingredient helps your skin hold onto moisture and stay resilient against irritation.

One in-vitro study found that this ingredient tells your skin cells to produce more of the proteins (filaggrin, loricrin, and involucrin) for building a strong and healthy barrier. This study also found this ingredient to be a solid antioxidant that helped neutralize damage against UV and pollution.

A study with people from 2010 found that sensitive, reactive skin using a cream with 10% of this ingredient for a month became noticeably less dry, less reactive, and harder to irritate compared to the group using a plain cream.

In short, this ingredient is a well-tolerated ingredient that can help with barrier repair, antioxidant protection, and calming reactive skin.

This ingredient is generally considered fungal acne (Malassezia) safe; Bifidobacterium is a bacterium, not a yeast or fungus.

The fungal acne concern with fermented ingredients mainly applies to yeast-derived ferments like Saccharomyces and Galactomyces, because those are in the same kingdom as Malassezia and could theoretically contain residual compounds that feed it.

Bifida is a completely different organism, so on its own it doesn't provide a food source for the Malassezia yeast that causes fungal acne.

Bis-Peg-18 Methyl Ether Dimethyl Silane belongs to the siloxanes and silicones classes. It is synthetically created and has a waxy composition.

This ingredient is a humectant and emollient, meaning it helps hydrate the skin. Humectants draw moisture to your skin, while emollients prevent moisture from escaping.

Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient.

It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation.

A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin.

In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum.

You'll likely see use concentrations quite low, usually 0.1-0.2%.

Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin.

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

It is a humectant and helps add texture to products. It can make your product thicker.

As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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