Independent education resourceInformation here does not replace care from a qualified health professional.
Peptide Therapy GuideClear peptide education

Educational guide

SkinCeuticals Triple Lipid Restore 2:4:2 Versus iNNBEAUTY PROJECT 10 + 10 Moisturizer with 10% Vitamin C + 10% Peptide Complex + Ceramides

SkinCeuticals Triple Lipid Restore 2:4:2 Versus iNNBEAUTY PROJECT 10 + 10 Moisturizer with 10% Vitamin C + 10% Peptide Complex + Ceramides This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and softe

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

SkinCeuticals Triple Lipid Restore 2:4:2 Versus iNNBEAUTY PROJECT 10 + 10 Moisturizer with 10% Vitamin C + 10% Peptide Complex + Ceramides

This barrier-repair moisturizer is formulated around Cholesterol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles.

This anti-aging moisturizer is formulated around 3-O-Ethyl Ascorbic Acid and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and brighten dull-looking skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Hydrogenated Polyisobutene

Glycerin

Cholesterol

C12-15 Alkyl Benzoate

Ceramide NP

Helianthus Annuus Seed Oil Unsaponifiables

Bis-PEG-18 Methyl Ether Dimethyl Silane

Sodium Polyacrylate

PEG-10 Dimethicone

Nylon-12

Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone

Dimethicone/PEG-10/15 Crosspolymer

Phenoxyethanol

Disteardimonium Hectorite

Hydroxyethylpiperazine Ethane Sulfonic Acid

Ammonium Polyacryloyldimethyl Taurate

Chlorphenesin

Caprylyl Glycol

PEG/PPG-18/18 Dimethicone

Propylene Carbonate

Disodium EDTA

Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer

Adenosine

Dipropylene Glycol

Lavandula Angustifolia Oil

Rosmarinus Officinalis Leaf Oil

T-Butyl Alcohol

Mentha Piperita Oil

Sodium Citrate

Linalool

Isobutane

Ceramide EOP

BHT

Tocopherol

Limonene

Water, Dimethicone, Hydrogenated Polyisobutene, Glycerin, Cholesterol, C12-15 Alkyl Benzoate, Ceramide NP, Helianthus Annuus Seed Oil Unsaponifiables, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sodium Polyacrylate, PEG-10 Dimethicone, Nylon-12, Lauryl PEG-9 Polydimethylsiloxyethyl Dimethicone, Dimethicone/PEG-10/15 Crosspolymer, Phenoxyethanol, Disteardimonium Hectorite, Hydroxyethylpiperazine Ethane Sulfonic Acid, Ammonium Polyacryloyldimethyl Taurate, Chlorphenesin, Caprylyl Glycol, PEG/PPG-18/18 Dimethicone, Propylene Carbonate, Disodium EDTA, Acrylonitrile/Methyl Methacrylate/Vinylidene Chloride Copolymer, Adenosine, Dipropylene Glycol, Lavandula Angustifolia Oil, Rosmarinus Officinalis Leaf Oil, T-Butyl Alcohol, Mentha Piperita Oil, Sodium Citrate, Linalool, Isobutane, Ceramide EOP, BHT, Tocopherol, Limonene

Butyrospermum Parkii Butter

Caprylic/Capric/Myristic/Stearic Triglyceride

3-O-Ethyl Ascorbic Acid

Tapioca Starch

Cetearyl Alcohol

Arachidyl Alcohol

Squalane

Coco-Caprylate/Caprate

Pentaerythrityl Tetraisostearate

Tridecyl Trimellitate

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Tetrahexyldecyl Ascorbate

Caprylyl/Capryl Glucoside

Linoleic Acid

Citric Acid

Phytosterols

Glucose

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Behenyl Alcohol

Polyisobutene

Bis-Diglyceryl Polyacyladipate-2

Hydroxyacetophenone

1,2-Hexanediol

Cetearyl Glucoside

Arachidyl Glucoside

Carrageenan

Sorbitan Laurate

Sodium Phytate

C18-36 Acid Glycol Ester

C18-36 Acid Triglyceride

Water, Glycerin, Dimethicone, Butyrospermum Parkii Butter, Caprylic/Capric/Myristic/Stearic Triglyceride, C12-15 Alkyl Benzoate, 3-O-Ethyl Ascorbic Acid, Tapioca Starch, Cetearyl Alcohol, Arachidyl Alcohol, Squalane, Coco-Caprylate/Caprate, Pentaerythrityl Tetraisostearate, Tridecyl Trimellitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tetrahexyldecyl Ascorbate, Ceramide NP, Caprylyl Glycol, Caprylyl/Capryl Glucoside, Linoleic Acid, Citric Acid, Phytosterols, Glucose, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Behenyl Alcohol, Polyisobutene, Bis-Diglyceryl Polyacyladipate-2, Hydroxyacetophenone, 1,2-Hexanediol, Cetearyl Glucoside, Arachidyl Glucoside, Carrageenan, Sorbitan Laurate, Sodium Phytate, C18-36 Acid Glycol Ester, C18-36 Acid Triglyceride

Reviews

Be the first to review

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

C12-15 Alkyl Benzoate is a lightweight emollient made by combinig benzoic acid with fatty alcohols that are 12-15 carbons long.

In cosmetics, it plays several roles:

The Cosmetic Review Expert Panel has concluded the alkyl benzoate group to be safe as used in cosmetics; it wasn't found to be a skin irritant and unlikely to be absorbed due to its low water solubility.

This report recorded almost 1000 reported uses with concentrations up to 59% in leave-on products but your cosmetics will typically use 0.5-15% depending on the product.

It's often called a "SPF booster": this is because it keeps UV filters properly dissolved and evenly distributed to support a sunscreen's performance. It doesn't actually raise SPF on its own.

Overall, this ingredient is well tolerated.

This ingredient is fungal acne safe because it is an ester of benzoic acid.

Think of this ingredient as two parts stuck together: an oily part and an acid part. Malassezia only gets a meal when it can snip off a fatty acid to eat. With C12-15 Alkyl Benzoate, the acid part is benzoic acid, which isn't a fatty acid and which the yeast can't use as food.

Benzoic acid is actually used as a preservative to stop yeast from growing.

The oily part is a blend of C12-15 fatty alcohols but fatty alcohols in this size range can support only a little Malassezia growth (mostly for one species of Malassezia as well).

In the ingredient, those alcohols stay locked inside the molecule. The yeast can only reach them by snipping the benzoate bond, and that type of bond is harder for it to cut than a normal fatty bond.

So not much gets released. And whatever does get snipped comes packaged with benzoic acid, which discourages yeast growth.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Similar Comparisons

Connected reading

Helpful context for this guide

Source-derived material selected through this article’s indexed topics.

P

About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

View all articles →