iNNBEAUTY PROJECT 10 + 10 Moisturizer with 10% Vitamin C + 10% Peptide Complex + Ceramides Versus DRMTLGY Needle-Less Serum

iNNBEAUTY PROJECT 10 + 10 Moisturizer with 10% Vitamin C + 10% Peptide Complex + Ceramides Versus DRMTLGY Needle-Less Serum

This anti-aging moisturizer is formulated around 3-O-Ethyl Ascorbic Acid and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and brighten dull-looking skin.

This anti-aging serum is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Dimethicone

Butyrospermum Parkii Butter

Caprylic/Capric/Myristic/Stearic Triglyceride

C12-15 Alkyl Benzoate

3-O-Ethyl Ascorbic Acid

Tapioca Starch

Cetearyl Alcohol

Arachidyl Alcohol

Squalane

Coco-Caprylate/Caprate

Pentaerythrityl Tetraisostearate

Tridecyl Trimellitate

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-1

Tetrahexyldecyl Ascorbate

Ceramide NP

Caprylyl Glycol

Caprylyl/Capryl Glucoside

Linoleic Acid

Citric Acid

Phytosterols

Glucose

Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Behenyl Alcohol

Polyisobutene

Bis-Diglyceryl Polyacyladipate-2

Hydroxyacetophenone

1,2-Hexanediol

Cetearyl Glucoside

Arachidyl Glucoside

Carrageenan

Sorbitan Laurate

Sodium Phytate

C18-36 Acid Glycol Ester

C18-36 Acid Triglyceride

Water, Glycerin, Dimethicone, Butyrospermum Parkii Butter, Caprylic/Capric/Myristic/Stearic Triglyceride, C12-15 Alkyl Benzoate, 3-O-Ethyl Ascorbic Acid, Tapioca Starch, Cetearyl Alcohol, Arachidyl Alcohol, Squalane, Coco-Caprylate/Caprate, Pentaerythrityl Tetraisostearate, Tridecyl Trimellitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tetrahexyldecyl Ascorbate, Ceramide NP, Caprylyl Glycol, Caprylyl/Capryl Glucoside, Linoleic Acid, Citric Acid, Phytosterols, Glucose, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Behenyl Alcohol, Polyisobutene, Bis-Diglyceryl Polyacyladipate-2, Hydroxyacetophenone, 1,2-Hexanediol, Cetearyl Glucoside, Arachidyl Glucoside, Carrageenan, Sorbitan Laurate, Sodium Phytate, C18-36 Acid Glycol Ester, C18-36 Acid Triglyceride

Sodium Chondroitin Sulfate

Sodium Hyaluronate

Pisum Sativum Extract

Bambusa Vulgaris Leaf/Stem Extract

Ceramide EOP

Glucosamine Hcl

Glycosaminoglycans

Palmitoyl Tripeptide-5

Ceramide AP

Phytosphingosine

Cholesterol

Niacinamide

Sodium Lauroyl Lactylate

Methylglucoside Phosphate

Copper Lysinate/Prolinate

Panthenol

Tocopheryl Acetate

Phenoxyethanol

Polysorbate 20

Ethylhexylglycerin

Disodium EDTA

Butylene Glycol

Carbomer

Xanthan Gum

Water, Glycerin, Sodium Chondroitin Sulfate, Sodium Hyaluronate, Pisum Sativum Extract, Bambusa Vulgaris Leaf/Stem Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Ceramide EOP, Glucosamine Hcl, Glycosaminoglycans, Ceramide NP, Palmitoyl Tripeptide-5, Ceramide AP, Phytosphingosine, Cholesterol, Niacinamide, Sodium Lauroyl Lactylate, Methylglucoside Phosphate, Copper Lysinate/Prolinate, Panthenol, Tocopheryl Acetate, Phenoxyethanol, Polysorbate 20, Ethylhexylglycerin, Disodium EDTA, Butylene Glycol, Carbomer, Xanthan Gum

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging".

"Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age.

This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break down collagen and elastin.

Clinical testing showed statistically significant improvements in:

Studies also found the more of this ingredient used, the more your skin produces Collagen I, fibronectin, and hyaluronic acid.

You'll likely see this ingredient paired with Palmitoyl Tripeptide-1 in the well-known Matrixyl 3000 complex for enhanced anti-aging effects.

A 3% concentration applied twice daily for two months showed meaningful skin rejuvenation results in clinical panels.

Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne.

Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid.

That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference.

Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid.

In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing.

Human clinical data is promising, but modest:

A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm.

A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks.

You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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