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PURITO Luminous Ceramide Moisturizer Versus Nø Cosmetics All-In Barrier Cream

PURITO Luminous Ceramide Moisturizer Versus Nø Cosmetics All-In Barrier Cream This barrier-repair moisturizer is formulated around Ceramide NP and Panthenol to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around B

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

PURITO Luminous Ceramide Moisturizer Versus Nø Cosmetics All-In Barrier Cream

This barrier-repair moisturizer is formulated around Ceramide NP and Panthenol to strengthen the skin barrier and hydrate skin.

This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Panthenol to strengthen the skin barrier and calm redness.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Glycerin

Caprylic/Capric Triglyceride

Hydrogenated Poly(C6-14 Olefin)

Behenyl Alcohol

Limnanthes Alba Seed Oil

Polyglyceryl-6 Stearate

1,2-Hexanediol

Cetyl Alcohol

Candida/Garcinia Cambogia Ferment

Ceramide NP

Glyceryl Stearate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Polyglyceryl-6 Behenate

Allantoin

Squalane

Caprylyl Glycol

Panthenol

Macadamia Ternifolia Seed Oil

Xanthan Gum

Butyrospermum Parkii Butter

Ethylhexylglycerin

Disodium EDTA

Dipropylene Glycol

Hydrogenated Lecithin

Ceramide Ns

Ceramide As

Ceramide AP

Cholesterol

Ceramide EOP

Water, Propanediol, Glycerin, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Behenyl Alcohol, Limnanthes Alba Seed Oil, Polyglyceryl-6 Stearate, 1,2-Hexanediol, Cetyl Alcohol, Candida/Garcinia Cambogia Ferment, Ceramide NP, Glyceryl Stearate, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyglyceryl-6 Behenate, Allantoin, Squalane, Caprylyl Glycol, Panthenol, Macadamia Ternifolia Seed Oil, Xanthan Gum, Butyrospermum Parkii Butter, Ethylhexylglycerin, Disodium EDTA, Dipropylene Glycol, Hydrogenated Lecithin, Ceramide Ns, Ceramide As, Ceramide AP, Cholesterol, Ceramide EOP

Cetearyl Alcohol

Simmondsia Chinensis Seed Oil

Dicaprylyl Ether

Prunus Armeniaca Kernel Oil

C13-15 Alkane

Pentylene Glycol

Cetearyl Olivate

Argania Spinosa Kernel Oil

Diglycerin

Ectoin

Sucrose Distearate

Heterotheca Inuloides Flower Extract

Sorbitan Olivate

Sea Water

Laminaria Digitata Extract

Chlorella Vulgaris Extract

Saccharide Isomerate

Hydroxyacetophenone

Phenoxyethanol

Lactic Acid

Citric Acid

Water, Butyrospermum Parkii Butter, Panthenol, Cetearyl Alcohol, Simmondsia Chinensis Seed Oil, Dicaprylyl Ether, Glycerin, Glyceryl Stearate, Prunus Armeniaca Kernel Oil, C13-15 Alkane, Propanediol, Pentylene Glycol, Cetearyl Olivate, Argania Spinosa Kernel Oil, Diglycerin, Ectoin, Ceramide EOP, Ceramide Ns, Ceramide NP, Ceramide As, Ceramide AP, Cholesterol, Hydrogenated Lecithin, Sucrose Distearate, Heterotheca Inuloides Flower Extract, Dipropylene Glycol, Sorbitan Olivate, Sea Water, Laminaria Digitata Extract, Chlorella Vulgaris Extract, Saccharide Isomerate, Xanthan Gum, Hydroxyacetophenone, Phenoxyethanol, Ethylhexylglycerin, Lactic Acid, Citric Acid

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients.

Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL).

In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!).

Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo.

Shea butter also contains vitamins A and E which may contribute to antioxidant activity.

While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement.

This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize.

Ceramide AP is is a skin-identical lipid that mimics what your skin already makes naturally. Ceramides help maintain epidermal integrity and barrier function.

You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has.

The skin's ability to produce ceramides gets disrupted in skin conditions like eczema. This in turn weakens the skin barrier and applying ceramides topically has been shown to replenish what's been lost to restore barrier function.

Most of the studies with Ceramide AP test it as part of a multi-ceramide complex; studies reinforce ceramide AP's role in rebalancing ceramides in skin and improving skin hydration.

Ceramide AS is formally known as Ceramides 4 and 5.

Ceramides are intercellular lipids naturally found in our skin that bonds dead skin cells together to create a barrier. They are known for their ability to hold water and thus are a great ingredient for dry skin.

Ceramide EOP is formally known as Ceramide 1.

It is naturally found in skin and part of the intercellular "mortar" holding everything together in your outermost layer.

EOP stands for a linked Ester fatty acid, a linked Omega hydroxy fatty acid, and the Phytosphingosine base.

What makes Ceramide EOP special is its ultra-long fatty acid chain; this unique structure allows it to bridge the lipid layers in your skin barrier to prevent water loss (something no other ceramide can do).

Low levels of Ceramide EOP have been found in people with eczema and psoriasis.

Using it together with other ceramides, cholesterol, and linoleic acid have been shown to meaningfully improve hydration and reduce water loss.

In one clinical study, a regimen using Ceramide EOP, NP, and AP led to significant symptom improvements in patients with eczema, psoriasis, and dry skin in just 4 weeks.

You'll usually see concentrations between 0.1-0.5% in formulations. Overall, this is a well-tolerated and safe ingredient for cosmetic use.

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Ceramide NS is formally known as Ceramide 2. It is one of the major ceramides in the stratum corneum (outermost layer of skin) plays a role in forming a protective barrier.

Due to its structure, skin lipids can be packed tightly and in turn, this strengthens the barrier and reduces water loss.

Studies show conditions like atopic dermatitis can worsen when ceramide NS levels are low.

Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.

It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).

This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.

Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.

Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.

Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Hydrogenated Lecithin is a more stable version of lecithin.

It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.

This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.

Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.

Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.

A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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