Educational guide
PepMix HCV (Capsid Protein) Ultra Peptide Pool
PepMix™ HCV (Capsid Protein) Ultra US$877.50 Excluding tax and shipping fees In stock Description About PepMix™ HCV (Capsid Protein) Ultra Pool of 140 peptides derived from a peptide scan (15mers with 11 aa overlap) through Capsid protein of Hepatitis C Virus
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PepMix™ HCV (Capsid Protein) Ultra
US$877.50
Excluding tax and shipping fees
In stock
Description
About PepMix™ HCV (Capsid Protein) Ultra
Pool of 140 peptides derived from a peptide scan (15mers with 11 aa overlap) through Capsid protein of Hepatitis C Virus (HCV).
PepMix™ HCV (Capsid Protein) Ultra - Specifications
Amount: 25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)
Purity: Development Grade: each peptide purified to > 70% (HPLC/MS) - (equivalent to an average purity of 85%)
Delivery Format: Freeze-dried in glass vial
Application(s): T-cell Immunity
Condition(s)/Topic(s): Hepatitis, Infection, Sequence diversity
Standard Delivery Time: 2-5 days
Are you interested in your own custom PepMix? Choose your sequence, amount, purity and pool format. We will assist you along the way. Custom PepMix Peptide Pools.
PepMix™ Peptide PoolsProtein-spanning mixtures of overlapping peptides (PepMix™) are extremely efficient for- Antigen-specific T cell stimulation in T cell assays (e.g. in ELISpot, ICS, cell-mediated cytotoxicity or proliferation assays)- In-vitro T cell expansion- Dendritic cell pulsing- Immune monitoring- Cellular immune response profiling- T cell epitope identification- Standardization of T cell assays
Benefits of PepMix™- Each peptide quality controlled and guaranteed for identity and purity- CoA and HPLC-MS data available- High batch-to-batch consistency- No false positive T cell responses by contaminating deletion peptides- No toxic inhibition of T cell responses due to stringent purification of each peptide- Minimization of endotoxin contamination due to low bioburden process- ADCF policy in place- HLA independent stimulation (with antigen spanning peptide pools)
References
References for PepMix™ HCV (Capsid Protein) Ultra
ReferencesRead References with PepMix™ Peptide Pools for Infectious Diseases COVID-19 related PepMixes™ PepMix™ Control Pools
Application NotesCross-reactive T cells enhance immune responses in SARS-CoV-2 infection and vaccinationLoyal et al (2021) Full textPeptide Tools to Support the Fight against COVID-19Alem et al (2020) Full textCEFX/EFX Ultra SuperStim Pools: Superior positive controls for T-cell assays with broad MHC-allele and antigen coverageEckey et al. (2017) Full textDeveloping Multi-HIV Antigen Specific T-Cells as a Component of a Cure StrategyLam et al. (2015) Full textPeptide-stimulated Expansion of Virus-specific T cells For Preventative Treatment After Allogeneic Stem Cell TransplantationGary et al. (2015) Full textPepMix™ Peptide Pools for Clinical Applications: T Cell Therapy for Viral Infections after Hematopoietic Stem Cell TransplantKeirnan et al. (2012) Full textCytomegalovirus Protein Spanning PepMix™ Peptide Pools to Discover Changes in T-Cell Immunity in the Aging PopulationKern (2012) Full text
Testimonials "To establish a novel role for myeloid derived suppressor cells (Pallett et al, Nat. Med. 2015) in chronic viral infection, we utilised the PepMix CEF Pool (extended) as well as a custom synthesized PepMix spanning the core region of HBV genotype D . Whereas, the CEF peptide pool consists of 32 peptides, each corresponding to a defined HLA class I-restricted T-cell epitope from Cytomegalo, Epstein-Barr, and Influenza virus, the latter custom PepMix included 15meric peptides overlapping by 10 amino acids. Specifically this composition enabled us to monitor both the antiviral CD8+ and CD4+ T cell responses in chronic HBV infection and the non-antigen specific T cells that are known to mediate immunopathology in the liver. Our entire experience with JPT, from ordering/delivery to use in the lab was excellent. Not only were the reagents able to perform reliably and consistently in vitro from batch to batch, the customer and technical support provided was continually available and efficient when needed. JPT will remain our go-to company for purchasing peptides." Dr. Laura J Pallett, Infection and Immunity, University College London, UK
Documentation
Documentation for PepMix™ HCV (Capsid Protein) Ultra
Protocol_PepMix.pdf
PM-HCV-Capsid-Protein.pdf
HCV-C-ULTRA-Annotations.pdf
Properties
Properties of PepMix™ HCV (Capsid Protein) Ultra
25 µg (approx. 15 nmol) / peptide (for stimulation of up to 2,5 x 108 cells)
T-cell immunity
PepMix Peptide Pools, PepMix Ultra Peptide Pools
Hepatitis, Infection, Sequence diversity
Freeze-dried in glass vial
Hepatitis C Virus (HCV)
Capsid protein
>70% (HPLC-MS), Development Grade: each peptide purified to > 70% (HPLC/MS)
No
Further Information to PepMix™ HCV (Capsid Protein) Ultra
Values
see additional product documentation
15 mer peptides generated via ULTRA algorithm for optimal sequence coverage
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