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MediCube Collagen Jelly Cream Versus Biologique Recherche Crème Dermopurifiante Purifying Face Cream

MediCube Collagen Jelly Cream Versus Biologique Recherche Crème Dermopurifiante Purifying Face Cream This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles. This oil-control moisturizer is formulated around Niacinamide to b

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

MediCube Collagen Jelly Cream Versus Biologique Recherche Crème Dermopurifiante Purifying Face Cream

This anti-aging moisturizer is formulated around Niacinamide to soften the look of wrinkles.

This oil-control moisturizer is formulated around Niacinamide to balance excess oil and clear breakouts.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Propanediol

Dipropylene Glycol

Butylene Glycol

Methylpropanediol

Diethoxyethyl Succinate

Ethoxydiglycol

Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer

Niacinamide

Trehalose

1,2-Hexanediol

Chlorella Vulgaris Extract

Collagen

Hydrolyzed Collagen

Cynanchum Atratum Extract

Althaea Rosea Flower Extract

Soluble Collagen

Allium Sativum Bulb Extract

Avena Sativa Kernel Extract

Bertholletia Excelsa Seed Extract

Brassica Oleracea Italica Extract

Camellia Sinensis Seed Extract

Salmon Egg Extract

Solanum Lycopersicum Fruit Extract

Spinacia Oleracea Leaf Extract

Vaccinium Angustifolium Fruit Extract

Wine Extract

Polyglyceryl-10 Isostearate

Tromethamine

Glucose

Polyglyceryl-10 Oleate

Ethylhexylglycerin

Fructooligosaccharides

Fructose

Adenosine

Sodium Phytate

Cyanocobalamin

Tocopherol

Pullulan

Glycerin

Hydroxypropyltrimonium Hyaluronate

Squalane

Soluble Proteoglycan

Hydrolyzed Elastin

Sodium DNA

Carbomer

Xanthan Gum

Parfum

Water, Propanediol, Dipropylene Glycol, Butylene Glycol, Methylpropanediol, Diethoxyethyl Succinate, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate/Beheneth-25 Methacrylate Crosspolymer, Niacinamide, Trehalose, 1,2-Hexanediol, Chlorella Vulgaris Extract, Collagen, Hydrolyzed Collagen, Cynanchum Atratum Extract, Althaea Rosea Flower Extract, Soluble Collagen, Allium Sativum Bulb Extract, Avena Sativa Kernel Extract, Bertholletia Excelsa Seed Extract, Brassica Oleracea Italica Extract, Camellia Sinensis Seed Extract, Salmon Egg Extract, Solanum Lycopersicum Fruit Extract, Spinacia Oleracea Leaf Extract, Vaccinium Angustifolium Fruit Extract, Wine Extract, Polyglyceryl-10 Isostearate, Tromethamine, Glucose, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Fructooligosaccharides, Fructose, Adenosine, Sodium Phytate, Cyanocobalamin, Tocopherol, Pullulan, Glycerin, Hydroxypropyltrimonium Hyaluronate, Squalane, Soluble Proteoglycan, Hydrolyzed Elastin, Sodium DNA, Carbomer, Xanthan Gum, Parfum

Propylene Glycol

Dicaprylyl Carbonate

Sucrose Polystearate

C10-18 Triglycerides

Cetyl Alcohol

Polyamide-5

Arctium Lappa Root Extract

Betula Alba Bark Extract

Enantia Chlorantha Bark Extract

Equisetum Arvense Extract

Mimosa Tenuiflora Bark Extract

Hedera Helix Leaf/Stem Extract

Fucus Vesiculosus Extract

Centella Asiatica Extract

Spiraea Ulmaria Extract

Arnica Montana Flower Extract

Rosa Canina Fruit Extract

Achillea Millefolium Extract

Aesculus Hippocastanum Seed Extract

Lavandula Angustifolia Flower Extract

Thymus Vulgaris Flower/Leaf Extract

Myrtus Communis Extract

Allium Cepa Bulb Extract

Commiphora Myrrha Resin Extract

Oleanolic Acid

Glycine Soja Oil

Yeast Extract

Citric Acid

Sodium Stearoyl Glutamate

Hydrogenated Polyisobutene

Polyacrylate Crosspolymer-6

T-Butyl Alcohol

Caprylyl Glycol

Phenoxyethanol

Sodium Benzoate

Potassium Sorbate

Sorbic Acid

Water, Propylene Glycol, Glycerin, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, 1,2-Hexanediol, Niacinamide, Polyamide-5, Arctium Lappa Root Extract, Betula Alba Bark Extract, Enantia Chlorantha Bark Extract, Equisetum Arvense Extract, Mimosa Tenuiflora Bark Extract, Hedera Helix Leaf/Stem Extract, Fucus Vesiculosus Extract, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Achillea Millefolium Extract, Aesculus Hippocastanum Seed Extract, Lavandula Angustifolia Flower Extract, Thymus Vulgaris Flower/Leaf Extract, Myrtus Communis Extract, Allium Cepa Bulb Extract, Commiphora Myrrha Resin Extract, Oleanolic Acid, Glycine Soja Oil, Yeast Extract, Citric Acid, Tocopherol, Sodium Stearoyl Glutamate, Hydrogenated Polyisobutene, Polyacrylate Crosspolymer-6, T-Butyl Alcohol, Caprylyl Glycol, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate, Sorbic Acid

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Tocopherol is a fat-soluble antioxidant known as Vitamin E.

You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.

Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.

It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.

This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.

Concentrations usually range from 0.1-1% in most leave-on products.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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