Educational guide
MEDI-PEEL Peptide9 Volume White Cica Essence Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
MEDI-PEEL Peptide9 Volume White Cica Essence Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum This anti-aging essence is formulated around Niacinamide and Centella Asiatica Extract to soften the look of wrinkles and calm redn
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MEDI-PEEL Peptide9 Volume White Cica Essence Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum
This anti-aging essence is formulated around Niacinamide and Centella Asiatica Extract to soften the look of wrinkles and calm redness.
This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Glycerin
Methylpropanediol
Methyl Perfluoroisobutyl Ether
Hydrogenated Polyisobutene
Butylene Glycol Dicaprylate/Dicaprate
Caprylic/Capric Triglyceride
Methyl Perfluorobutyl Ether
Niacinamide
Cyclopentasiloxane
Cetearyl Alcohol
Cyclohexasiloxane
Elaeis Guineensis Oil
Sodium Myristoyl Glutamate
Arginine
Glyceryl Stearate
PEG-100 Stearate
Decyl Glucoside
Betaine
Hydrogenated Lecithin
Hydroxyethyl Urea
Elaeis Guineensis Kernel Oil
Dimethicone
Decylene Glycol
Ammonium Acryloyldimethyltaurate/Vp Copolymer
Myristic Acid
Hexylene Glycol
Carbomer
Propanediol
Eucalyptus Globulus Leaf Extract
Juniperus Communis Fruit Extract
Butylene Glycol
Dimethicone/Vinyl Dimethicone Crosspolymer
Glyceryl Acrylate/Acrylic Acid Copolymer
Sodium Hyaluronate Crosspolymer
Urea
Allantoin
Ammonium Lactate
Adenosine
Sodium Hyaluronate
Hydrolyzed Glycosaminoglycans
Laureth-23
Propylene Glycol
Disodium EDTA
Buteth-3
Centella Asiatica Extract
Centella Asiatica Leaf Extract
Anthemis Nobilis Flower Water
Argania Spinosa Kernel Oil
Camellia Sinensis Leaf Extract
Magnolia Officinalis Bark Extract
Fructan
Taraxacum Officinale Rhizome/Root Extract
Sodium Benzotriazolyl Butylphenol Sulfonate
Benzyl Glycol
Alcohol Denat.
Decyl Alcohol
Tris(Tetramethylhydroxypiperidinol)Citrate
Hydrolyzed Hyaluronic Acid
Glucose
Desamido Collagen
Hydrolyzed Collagen
Tranexamic Acid
Tributyl Citrate
Trideceth-6
Sodium Polyacrylate
Pentylene Glycol
Hydrogenated Polydecene
Glyceryl Polymethacrylate
Anemarrhena Asphodeloides Root Extract
Chamaecyparis Obtusa Leaf Extract
Asiaticoside
Origanum Vulgare Leaf Extract
Salix Alba Bark Extract
Hyaluronic Acid
Lactobacillus/Soybean Ferment Extract
Cinnamomum Cassia Bark Extract
Scutellaria Baicalensis Root Extract
Portulaca Oleracea Extract
Sorbitan Laurate
Polysorbate 20
Raspberry Ketone
Polysorbate 80
Chondrus Crispus Extract
Hydroxyethylcellulose
Acetyl Dipeptide-1 Cetyl Ester
Astaxanthin
Hydrolyzed Elastin
Palmitoyl Tripeptide-5
Madecassoside
Madecassic Acid
Acetyl Hexapeptide-8
Copper Tripeptide-1
Asiatic Acid
Oligopeptide-29
Oligopeptide-32
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Palmitoyl Oligopeptide
Palmitoyl Pentapeptide-4
1,2-Hexanediol
Ethylhexylglycerin
Totarol
Caprylyl Glycol
Parfum
CI 42090
CI 15985
CI 19140
Water, Glycerin, Methylpropanediol, Methyl Perfluoroisobutyl Ether, Hydrogenated Polyisobutene, Butylene Glycol Dicaprylate/Dicaprate, Caprylic/Capric Triglyceride, Methyl Perfluorobutyl Ether, Niacinamide, Cyclopentasiloxane, Cetearyl Alcohol, Cyclohexasiloxane, Elaeis Guineensis Oil, Sodium Myristoyl Glutamate, Arginine, Glyceryl Stearate, PEG-100 Stearate, Decyl Glucoside, Betaine, Hydrogenated Lecithin, Hydroxyethyl Urea, Elaeis Guineensis Kernel Oil, Dimethicone, Decylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Myristic Acid, Hexylene Glycol, Carbomer, Propanediol, Eucalyptus Globulus Leaf Extract, Juniperus Communis Fruit Extract, Butylene Glycol, Dimethicone/Vinyl Dimethicone Crosspolymer, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium Hyaluronate Crosspolymer, Urea, Allantoin, Ammonium Lactate, Adenosine, Sodium Hyaluronate, Hydrolyzed Glycosaminoglycans, Laureth-23, Propylene Glycol, Disodium EDTA, Buteth-3, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Anthemis Nobilis Flower Water, Argania Spinosa Kernel Oil, Camellia Sinensis Leaf Extract, Magnolia Officinalis Bark Extract, Fructan, Taraxacum Officinale Rhizome/Root Extract, Sodium Benzotriazolyl Butylphenol Sulfonate, Benzyl Glycol, Alcohol Denat., Decyl Alcohol, Tris(Tetramethylhydroxypiperidinol)Citrate, Hydrolyzed Hyaluronic Acid, Glucose, Desamido Collagen, Hydrolyzed Collagen, Tranexamic Acid, Tributyl Citrate, Trideceth-6, Sodium Polyacrylate, Pentylene Glycol, Hydrogenated Polydecene, Glyceryl Polymethacrylate, Anemarrhena Asphodeloides Root Extract, Chamaecyparis Obtusa Leaf Extract, Asiaticoside, Origanum Vulgare Leaf Extract, Salix Alba Bark Extract, Hyaluronic Acid, Lactobacillus/Soybean Ferment Extract, Cinnamomum Cassia Bark Extract, Scutellaria Baicalensis Root Extract, Portulaca Oleracea Extract, Sorbitan Laurate, Polysorbate 20, Raspberry Ketone, Polysorbate 80, Chondrus Crispus Extract, Hydroxyethylcellulose, Acetyl Dipeptide-1 Cetyl Ester, Astaxanthin, Hydrolyzed Elastin, Palmitoyl Tripeptide-5, Madecassoside, Madecassic Acid, Acetyl Hexapeptide-8, Copper Tripeptide-1, Asiatic Acid, Oligopeptide-29, Oligopeptide-32, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Oligopeptide, Palmitoyl Pentapeptide-4, 1,2-Hexanediol, Ethylhexylglycerin, Totarol, Caprylyl Glycol, Parfum, CI 42090, CI 15985, CI 19140
Bifida Ferment Lysate
PEG-8
Bis-PEG-18 Methyl Ether Dimethyl Silane
Methyl Gluceth-20
Glycereth-26
PEG-75
Adansonia Digitata Seed Extract
Tripeptide-32
Faex Extract
Lactobacillus Ferment
Cola Acuminata Seed Extract
Anthemis Nobilis Flower Extract
Hydrolyzed Algin
Pantethine
Caffeine
Lecithin
Sodium Rna
Bisabolol
Squalane
Oleth-3 Phosphate
Oleth-3
Oleth-5
Choleth-24
Jojoba Wax PEG-120 Esters
Ceteth-24
Tocopheryl Acetate
Triethanolamine
Tetrasodium EDTA
BHT
Xanthan Gum
Potassium Sorbate
Phenoxyethanol
CI 14700
Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
CI 19140 is also known as Tartrazine. Tartrazine is a synthetic dye used in cosmetics, foods, and medicine to add a yellow color.
Tartrazine is created from petroleum and is water-soluble.
Some people may experience allergies from this dye, especially asthmatics and those with an aspirin intolerance.
Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.
This ingredient mainly works behind the scenes and helps with:
On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.
One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).
Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.
You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!