MEDI-PEEL Peptide 9 Volumn Lif-Tox Eye Cream Versus Abib Collagen Eye Crème Jericho Rose Tube

MEDI-PEEL Peptide 9 Volumn Lif-Tox Eye Cream Versus Abib Collagen Eye Crème Jericho Rose Tube

This anti-aging eye moisturizer is formulated around Niacinamide and Acetyl Hexapeptide-8 to soften the look of wrinkles.

This anti-aging eye moisturizer is formulated around Niacinamide and Collagen Extract to soften the look of wrinkles and hydrate skin.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Cetyl Ethylhexanoate

Salvia Officinalis Extract

Glycerin

Niacinamide

Dipropylene Glycol

Polyglyceryl-3 Methylglucose Distearate

Cyclohexasiloxane

Cetearyl Alcohol

Stearic Acid

1,2-Hexanediol

Olea Europaea Fruit Oil

Butyrospermum Parkii Butter

Panthenol

Tremella Fuciformis Extract

Pimpinella Anisum Seed Extract

Salmon Egg Extract

Butylene Glycol

Juniperus Oxycedrus Wood Extract

Carnosine

Hydrolyzed Soy Protein

Acetyl Hexapeptide-8

Copper Tripeptide-1

Palmitoyl Pentapeptide-4

Tripeptide-1

Palmitoyl Tripeptide-1

Hexapeptide-9

Nonapeptide-1

Palmitoyl Tetrapeptide-7

Palmitoyl Tripeptide-5

Leontopodium Alpinum Callus Culture Extract

Camellia Sinensis Leaf Extract

Centella Asiatica Extract

Glycyrrhiza Glabra Root Extract

Golden Extract

Rosa Canina Fruit Extract

Chamomilla Recutita Extract

Rosmarinus Officinalis Leaf Extract

Lactobacillus

Salix Alba Bark Extract

Cinnamomum Zeylanicum Bark Extract

Origanum Vulgare Leaf Extract

Cupressus Sempervirens Leaf Extract

Portulaca Oleracea Extract

Hydrogenated Polyisobutene

Ulmus Davidiana Root Extract

Hydroxypropyltrimonium Hyaluronate

Sodium Acetylated Hyaluronate

Hydrolyzed Hyaluronic Acid

Hyaluronic Acid

Sodium Hyaluronate Crosspolymer

Hydrolyzed Sodium Hyaluronate

Potassium Hyaluronate

Hydrolyzed Collagen

Royal Jelly Extract

Argania Spinosa Kernel Oil

Squalane

Ceramide NP

Tocopheryl Acetate

Adenosine

Disodium EDTA

Betaine

Sodium Hyaluronate

Carbomer

Ethylhexylglycerin

Glyceryl Stearate

Tromethamine

Sodium Polyacrylate

Ethylhexyl Stearate

Trideceth-6

Pentylene Glycol

Caprylyl Glycol

Hydroxyacetophenone

Dipotassium Glycyrrhizate

Parfum

Water, Cetyl Ethylhexanoate, Salvia Officinalis Extract, Glycerin, Niacinamide, Dipropylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Cyclohexasiloxane, Cetearyl Alcohol, Stearic Acid, 1,2-Hexanediol, Olea Europaea Fruit Oil, Butyrospermum Parkii Butter, Panthenol, Tremella Fuciformis Extract, Pimpinella Anisum Seed Extract, Salmon Egg Extract, Butylene Glycol, Juniperus Oxycedrus Wood Extract, Carnosine, Hydrolyzed Soy Protein, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Pentapeptide-4, Tripeptide-1, Palmitoyl Tripeptide-1, Hexapeptide-9, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Leontopodium Alpinum Callus Culture Extract, Camellia Sinensis Leaf Extract, Centella Asiatica Extract, Glycyrrhiza Glabra Root Extract, Golden Extract, Rosa Canina Fruit Extract, Chamomilla Recutita Extract, Rosmarinus Officinalis Leaf Extract, Lactobacillus, Salix Alba Bark Extract, Cinnamomum Zeylanicum Bark Extract, Origanum Vulgare Leaf Extract, Cupressus Sempervirens Leaf Extract, Portulaca Oleracea Extract, Hydrogenated Polyisobutene, Ulmus Davidiana Root Extract, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate, Hydrolyzed Collagen, Royal Jelly Extract, Argania Spinosa Kernel Oil, Squalane, Ceramide NP, Tocopheryl Acetate, Adenosine, Disodium EDTA, Betaine, Sodium Hyaluronate, Carbomer, Ethylhexylglycerin, Glyceryl Stearate, Tromethamine, Sodium Polyacrylate, Ethylhexyl Stearate, Trideceth-6, Pentylene Glycol, Caprylyl Glycol, Hydroxyacetophenone, Dipotassium Glycyrrhizate, Parfum

Octyldodecanol

Caprylyl Methicone

Caprylic/Capric Triglyceride

Pentaerythrityl Tetraethylhexanoate

Behenyl Alcohol

Methylpropanediol

Polymethylsilsesquioxane

Macadamia Integrifolia Seed Oil

Cetearyl Olivate

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer

Sorbitan Olivate

Mangifera Indica Seed Butter

Polyglyceryl-3 Distearate

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Bis-Diglyceryl Polyacyladipate-2

Stearyl Alcohol

Cetearyl Glucoside

Xanthan Gum

Sorbitan Isostearate

Anastatica Hierochuntica Extract

Allantoin

Glyceryl Stearate Citrate

Trisodium Ethylenediamine Disuccinate

Hydrogenated Lecithin

Lactobacillus Ferment

Hippophae Rhamnoides Oil

Tocopherol

Collagen Extract

Bakuchiol

Caffeine

Trehalose

Macadamia Ternifolia Seed Oil

Polyglyceryl-10 Laurate

Phosphatidylcholine

Asiaticoside

Phytosphingosine

Asiatic Acid

Glycolipids

Madecassic Acid

Sorbitol

Bifida Ferment Filtrate

Water, Glycerin, Niacinamide, Octyldodecanol, Caprylyl Methicone, Caprylic/Capric Triglyceride, Pentaerythrityl Tetraethylhexanoate, Pentylene Glycol, Polyglyceryl-3 Methylglucose Distearate, Behenyl Alcohol, Methylpropanediol, Polymethylsilsesquioxane, 1,2-Hexanediol, Panthenol, Macadamia Integrifolia Seed Oil, Cetearyl Olivate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sorbitan Olivate, Glyceryl Stearate, Mangifera Indica Seed Butter, Polyglyceryl-3 Distearate, Cetearyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Bis-Diglyceryl Polyacyladipate-2, Stearyl Alcohol, Caprylyl Glycol, Cetearyl Glucoside, Squalane, Ethylhexylglycerin, Dipotassium Glycyrrhizate, Xanthan Gum, Sorbitan Isostearate, Anastatica Hierochuntica Extract, Adenosine, Allantoin, Glyceryl Stearate Citrate, Trisodium Ethylenediamine Disuccinate, Hydrogenated Lecithin, Lactobacillus Ferment, Hippophae Rhamnoides Oil, Ceramide NP, Tocopherol, Collagen Extract, Sodium Hyaluronate, Bakuchiol, Caffeine, Trehalose, Dipropylene Glycol, Macadamia Ternifolia Seed Oil, Butylene Glycol, Polyglyceryl-10 Laurate, Phosphatidylcholine, Asiaticoside, Phytosphingosine, Asiatic Acid, Glycolipids, Madecassic Acid, Palmitoyl Tripeptide-5, Sorbitol, Bifida Ferment Filtrate

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.

The way it works is fairly well mapped out:

Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.

The clinical backing is pretty solid too.

A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.

A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.

On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.

This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.

Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids.

Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes.

This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants.

A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%.

Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days.

Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient.

Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically.

Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier.

Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient.

It plays several roles in a formula:

Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products.

Multiple assessments have found it to be non-irritating and non-sensitizing to most people.

However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers.

Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy.

Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans.

Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients.

This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain lengths that fall within the range that Malassezia can metabolize.

A 2019 study has also observed Malassezia growth in the presence of this ingredient, confirming it to be not-fungal acne safe.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Dipropylene Glycol is a synthetically created humectant, stabilizer, and solvent.

This ingredient helps:

Dipropylene glycol is technically an alcohol, but it belongs to the glycol family (often considered part of the ‘good’ alcohols). This means it is hydrating and gentle on skin unlike drying solvent alcohols like denatured alcohol.

As a masking agent, Dipropylene Glycol can be used to cover the smell of other ingredients. However, it does not have a scent.

Studies show Dipropylene Glycol is considered safe to use in skincare.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive.

Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture.

This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic.

A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier.

Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range.

Fun fact: The human body also creates Glyceryl Stearate naturally.

Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.

And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.

You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.

In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.

If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.

When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.

When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.

In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).

Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.

Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.

The type of niacinamide used in skincare is synthetically created.

Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier.

This peptide has a "build more, lose less" approach.

It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein.

The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days.

This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers.

Typical use levels range from 1-3% and this ingredient gets along with pretty much everything.

On the fungal acne front: Although palmitic acid sits in the chain length that Malassezia can feed on, this ingredient has it locked in an amine bond. This makes it hard for Malassezia to access as a source of food, and therefore fungal acne safe.

Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair.

There are two forms of panthenol: D and L.

D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol.

Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons):

Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated.

This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds.

Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells.

This ingredient is also referred to as pro-vitamin B5.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Polyglyceryl-3 Methylglucose Distearate is a plant-derived emulsifier whose only job is to keep the oily and watery parts of a formula blended so it doesn't separate into layers.

It's compatible with a wide-range of active ingredients and especially good at making emulsions survive heat/freeze cycles.

Typical use concentrations range from 2-3% and it works across a pH of 4.5-8.5.

This ingredient has been found safe to use in cosmetics and has a low irritation profile.

Because it's build on stearic acid, it may not be fungal acne safe. Stearic acid is a C18 fatty acid that falls within the range (C11-24) that Malassezia can feed on.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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