Educational guide
MEDI-PEEL Peptide 9 Bio Sun Stick SPF 50+ PA+++ Versus SKIN1004 Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++
MEDI-PEEL Peptide 9 Bio Sun Stick SPF 50+ PA+++ Versus SKIN1004 Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++ This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. This chemical sunscreen covers the full UV range a
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MEDI-PEEL Peptide 9 Bio Sun Stick SPF 50+ PA+++ Versus SKIN1004 Madagascar Centella Hyalu-Cica Water-Fit Sun Serum SPF50+ PA++++
This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
This chemical sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Triethylhexanoin
Ceresin
Acrylates Copolymer
Water
Diethylamino Hydroxybenzoyl Hexyl Benzoate
Isononyl Isononanoate
Isoamyl Laurate
Dibutyl Adipate
Isoamyl P-Methoxycinnamate
Butyloctyl Salicylate
Caprylic/Capric Triglyceride
4-Methylbenzylidene Camphor
Ethylhexyl Palmitate
Euphorbia Cerifera Wax
Polymethyl Methacrylate
Ozokerite
Zinc Oxide
Titanium Dioxide
Glycerin
Niacinamide
Nylon-12
Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate
Microcrystalline Wax
Sorbitan Sesquioleate
1,2-Hexanediol
Bis-Diglyceryl Polyacyladipate-2
Sorbitan Olivate
Aluminum Hydroxide
Stearic Acid
Tocopherol
Butylene Glycol
Ethylhexylglycerin
Adenosine
Glycine Soja Oil
Disodium EDTA
Dioscorea Japonica Root Extract
Aloe Barbadensis Leaf Extract
Laminaria Japonica Extract
Ulmus Davidiana Root Extract
Viola Mandshurica Flower Extract
Polyglyceryl-3 Diisostearate
Fructan
Oryza Sativa Germ Extract
Oryza Sativa Extract
BHT
Cimicifuga Racemosa Root Extract
Angelica Gigas Root Extract
Glycyrrhiza Glabra Root Extract
Morus Alba Bark Extract
Phellinus Linteus Extract
Polygonum Multiflorum Root Extract
Paeonia Lactiflora Root Extract
Sophora Flavescens Root Extract
Scutellaria Baicalensis Root Extract
Sesamum Indicum Seed Extract
Pvp
Hydrogenated Polyisobutene
Cynanchum Atratum Extract
Lycopodium Clavatum Extract
Equisetum Arvense Extract
Propanediol
Biosaccharide Gum-4
Sodium Hyaluronate
Hydrolyzed Elastin
Atelocollagen
Desamido Collagen
Hydrolyzed Collagen
Hydroxypropyl Cyclodextrin
Polysorbate 80
Soluble Collagen
Hydrolyzed Hyaluronic Acid
Hydrolyzed Sodium Hyaluronate
Ubiquinone
Collagen
Collagen Amino Acids
Astaxanthin
Glutathione
Sodium Benzoate
Fullerenes
Hexapeptide-9
Acetyl Hexapeptide-8
Copper Tripeptide-1
Procollagen
Hydroxypropyltrimonium Hyaluronate
Nonapeptide-1
Palmitoyl Pentapeptide-4
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-5
Sodium Acetylated Hyaluronate
Tripeptide-1
Acetyl Tetrapeptide-2
Dimethylsilanol Hyaluronate
Anemarrhena Asphodeloides Root Extract
Sodium Hyaluronate Crosspolymer
Hyaluronic Acid
Pentylene Glycol
Potassium Hyaluronate
Parfum
Triethylhexanoin, Ceresin, Acrylates Copolymer, Water, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Isononyl Isononanoate, Isoamyl Laurate, Dibutyl Adipate, Isoamyl P-Methoxycinnamate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, 4-Methylbenzylidene Camphor, Ethylhexyl Palmitate, Euphorbia Cerifera Wax, Polymethyl Methacrylate, Ozokerite, Zinc Oxide, Titanium Dioxide, Glycerin, Niacinamide, Nylon-12, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Microcrystalline Wax, Sorbitan Sesquioleate, 1,2-Hexanediol, Bis-Diglyceryl Polyacyladipate-2, Sorbitan Olivate, Aluminum Hydroxide, Stearic Acid, Tocopherol, Butylene Glycol, Ethylhexylglycerin, Adenosine, Glycine Soja Oil, Disodium EDTA, Dioscorea Japonica Root Extract, Aloe Barbadensis Leaf Extract, Laminaria Japonica Extract, Ulmus Davidiana Root Extract, Viola Mandshurica Flower Extract, Polyglyceryl-3 Diisostearate, Fructan, Oryza Sativa Germ Extract, Oryza Sativa Extract, BHT, Cimicifuga Racemosa Root Extract, Angelica Gigas Root Extract, Glycyrrhiza Glabra Root Extract, Morus Alba Bark Extract, Phellinus Linteus Extract, Polygonum Multiflorum Root Extract, Paeonia Lactiflora Root Extract, Sophora Flavescens Root Extract, Scutellaria Baicalensis Root Extract, Sesamum Indicum Seed Extract, Pvp, Hydrogenated Polyisobutene, Cynanchum Atratum Extract, Lycopodium Clavatum Extract, Equisetum Arvense Extract, Propanediol, Biosaccharide Gum-4, Sodium Hyaluronate, Hydrolyzed Elastin, Atelocollagen, Desamido Collagen, Hydrolyzed Collagen, Hydroxypropyl Cyclodextrin, Polysorbate 80, Soluble Collagen, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Ubiquinone, Collagen, Collagen Amino Acids, Astaxanthin, Glutathione, Sodium Benzoate, Fullerenes, Hexapeptide-9, Acetyl Hexapeptide-8, Copper Tripeptide-1, Procollagen, Hydroxypropyltrimonium Hyaluronate, Nonapeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Sodium Acetylated Hyaluronate, Tripeptide-1, Acetyl Tetrapeptide-2, Dimethylsilanol Hyaluronate, Anemarrhena Asphodeloides Root Extract, Sodium Hyaluronate Crosspolymer, Hyaluronic Acid, Pentylene Glycol, Potassium Hyaluronate, Parfum
Polymethylsilsesquioxane
Ethylhexyl Triazone
Methylene Bis-Benzotriazolyl Tetramethylbutylphenol
Coco-Caprylate/Caprate
Caprylyl Methicone
Diethylhexyl Butamido Triazone
Behenyl Alcohol
Poly C10-30 Alkyl Acrylate
Polyglyceryl-3 Methylglucose Distearate
Decyl Glucoside
Tromethamine
Carbomer
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
Sodium Stearoyl Glutamate
Polyacrylate Crosspolymer-6
Xanthan Gum
Centella Asiatica Extract
T-Butyl Alcohol
Betula Platyphylla Japonica Bark Extract
Camellia Sinensis Leaf Extract
Ginkgo Biloba Leaf Extract
Brassica Oleracea Italica Sprout Extract
Camellia Japonica Leaf Extract
Eruca Sativa Leaf Extract
Medicago Sativa Extract
Triticum Vulgare Sprout Extract
Inositol
Water, Dibutyl Adipate, Propanediol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Polymethylsilsesquioxane, Ethylhexyl Triazone, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Niacinamide, Coco-Caprylate/Caprate, Caprylyl Methicone, Diethylhexyl Butamido Triazone, Glycerin, 1,2-Hexanediol, Butylene Glycol, Pentylene Glycol, Behenyl Alcohol, Poly C10-30 Alkyl Acrylate, Polyglyceryl-3 Methylglucose Distearate, Decyl Glucoside, Tromethamine, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Glutamate, Polyacrylate Crosspolymer-6, Ethylhexylglycerin, Adenosine, Xanthan Gum, Centella Asiatica Extract, T-Butyl Alcohol, Sodium Hyaluronate, Betula Platyphylla Japonica Bark Extract, Tocopherol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Extract, Ginkgo Biloba Leaf Extract, Brassica Oleracea Italica Sprout Extract, Camellia Japonica Leaf Extract, Eruca Sativa Leaf Extract, Medicago Sativa Extract, Triticum Vulgare Sprout Extract, Inositol, Hyaluronic Acid
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.
It is a:
Humectant, drawing moisture into the skin
Emollient, helping to soften skin
Solvent, dispersing and stabilizing formulas
Preservative booster, enhancing the antimicrobial activity of other preservatives
Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent.
The way it works is fairly well mapped out:
Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going.
The clinical backing is pretty solid too.
A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months.
A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration.
On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses.
This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization.
Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Dibutyl Adipate is a lightweight, oil-soluble ester that acts as an emollient and solvent. It helps products spread more easily and leaves a soft, silky, dry-touch finish without being greasy.
You'll likely see this ingredient in sunscreens because it does a nice job dissolving UV filters and keeping them evenly distributed.
This ingredient has been found to be safe as used in cosmetics, wasn't a skin or eye irritant in clinical patch testing, and wasn't phototoxic.
In a clinical comedogenicity test, this ingredient tested negative so it isn't likely to clog pores.
Typical use levels are about 5-8% for sunscreens + nail products, but can range from 0.005%-8% depending on the product.
Diethylamino Hydroxybenzoyl Hexyl Benzoate (DHHB) is a chemical UV-A absorber. It is formulated for high UVA protection (320-400 nm).
DHHB is well-liked for:
DHHB has been approved by the EU, Japan, Taiwan, and South America for use up to 10%. Unfortunately, it has not been approved for use in the US or Canada due to slow regulatory processes.
This ingredient is soluble in oils, fats, and lipids.
Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:
The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.
Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hyaluronic acid (HA) is a glycosaminoglycan (basically a long sugar chain) that your skin already makes on its own. In your skin, HA lives in the extracellular matrix and acts as the body's moisture reservoir.
Topically, HA is a humectant that binds water and helps skin look more plump, smooth, and hydrated.
The only catch is that HA isn't a single thing; it actually comes in a wide range of molecular weights (~50 - 2,000+ kDA) and size matters.
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
This is why the best HA serums blend the two sizes together so you get the best of both worlds.
The majority of cosmetic HA is produced by bacterial fermentation, typically using Streptococcus or Bacillus strains. Typical use levels in skincare sit around 0.1-2%.
A clinical study using a 0.2% low-molecular weight HA gel showed improvement in facial seborrheic dermatitis with excellent tolerance.
These are some other common types of Hyaluronic Acid:
Hydrolyzed Hyaluronic Acid is hyaluronic acid (HA) that is broken down into lower molecular weight fragments.
It's a humectant that pulls and holds water in the skin to help with hydration, plumpness, and reduce transepidermal water loss.
Because hydrolyzed hyaluronic acid is smaller in size, it can slip past your outermost layer of skin more easily than full-sized HA.
Most formulations will combine all sizes to get the best of both worlds.
Typical usage levels range from 0.01-1%. Any percentage higher than 2% might become goopy and tacky.
Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging.
And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin.
You might have heard of "niacin flush", or the reddening of skin that causes itchiness. Niacinamide has not been found to cause this.
In very rare cases, some individuals may not be able to tolerate niacinamide at all or experience an allergic reaction to it.
If you are experiencing flaking, irritation, and dryness with this ingredient, be sure to double check all your products as this ingredient can be found in all categories of skincare.
When incorporating niacinamide into your routine, look out for concentration amounts. Typically, 5% niacinamide provides benefits such as fading dark spots. However, if you have sensitive skin, it is better to begin with a smaller concentration.
When you apply niacinamide to your skin, your body converts it into nicotinamide adenine dinucleotide (NAD). NAD is an essential coenzyme that is already found in your cells as "fuel" and powers countless biological processes.
In your skin, NAD helps repair cell damage, produce new healthy cells, support collagen production, strengthen the skin barrier, and fight environmental stressors (like UV and pollution).
Our natural NAD levels start to decline with age, leading to slower skin repair, visible aging, and a weaker skin barrier. By providing your skin niacinamide, you're recharging your skin's NAD levels. This leads to stronger, healthier, and younger looking skin.
Another name for vitamin B3 is nicotinamide. This vitamin is water-soluble and our bodies don't store it. We obtain Vitamin B3 from either food or skincare. Meat, fish, wheat, yeast, and leafy greens contain vitamin B3.
The type of niacinamide used in skincare is synthetically created.
Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:
Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.
On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.
Typical use levels in a formula run about 1-5%.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Tocopherol is a fat-soluble antioxidant known as Vitamin E.
You'll find this ingredient in the vast majority of skincare (for good reason). It works to neutralize free radicals, or unstable molecules generated by UV exposure, pollution, and other environmental stressors, before they can cause oxidative damage to your skin cells.
Topically applied tocopherol has been shown to protect against UV damage by ramping up the skin's own natural defense enzymes.
It also acts as a skin conditioning agent; some studies show that regular topical use can improve the skin's water-binding capacity over 2-4 weeks.
This ingredient is especially loved for being a team player. When combined with Vitamin C, the photoprotective effect of both ingredients roughly doubles and the combo also helps reduce UV-induced DNA damage.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
In formulations, it also serves as a stabilizer that helps protect other oxidation-prone ingredients from degrading.
Concentrations usually range from 0.1-1% in most leave-on products.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!