Educational guide
La Mer The Moisturizing Soft Cream Versus Biologique Recherche Crème Masque Vernix Revitalizing, Regenerating and Protective Cream/Mask for the Face
La Mer The Moisturizing Soft Cream Versus Biologique Recherche Crème Masque Vernix Revitalizing, Regenerating and Protective Cream/Mask for the Face This barrier-repair moisturizer is formulated around Petrolatum and Cholesterol to strengthen the skin barrier
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
La Mer The Moisturizing Soft Cream Versus Biologique Recherche Crème Masque Vernix Revitalizing, Regenerating and Protective Cream/Mask for the Face
This barrier-repair moisturizer is formulated around Petrolatum and Cholesterol to strengthen the skin barrier and hydrate skin.
This barrier-repair moisturizer is formulated around Lecithin and Ceramide NP to strengthen the skin barrier and hydrate skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Algae Extract
Cyclopentasiloxane
Petrolatum
Glyceryl Distearate
Phenyl Trimethicone
Cyclohexasiloxane
Butylene Glycol
Cholesterol
Butyrospermum Parkii Butter
Steareth-10
Dimethicone
Glyceryl Stearate Se
Polysilicone-11
Glyceryl Triacetyl Ricinoleate
Macadamia Integrifolia Seed Oil
Glycerin
Sesamum Indicum Seed Oil
Medicago Sativa Seed Powder
Helianthus Annuus Seedcake
Prunus Amygdalus Dulcis Seed Meal
Eucalyptus Globulus Leaf Oil
Sodium Gluconate
Copper Gluconate
Calcium Gluconate
Magnesium Gluconate
Zinc Gluconate
Tocopheryl Succinate
Niacin
Sesamum Indicum Seed Powder
Water
Citrus Aurantifolia Peel Extract
Laminaria Digitata Extract
Crithmum Maritimum Extract
Salicornia Herbacea Extract
Plankton Extract
Chlorella Vulgaris Extract
Rosmarinus Officinalis Leaf Extract
Sodium Hyaluronate
Tocopheryl Acetate
Acetyl Hexapeptide-8
Caffeine
Tetrahexyldecyl Ascorbate
Palmitoyl Hexapeptide-12
Caprylic/Capric Triglyceride
Triethylhexanoin
Sodium PCA
Cetyl Alcohol
Diethylhexyl Succinate
Isocetyl Stearoyl Stearate
Cyanocobalamin
C13-14 Isoparaffin
Distearyldimonium Chloride
Dipalmitoyl Hydroxyproline
Sucrose
Hydrogenated Vegetable Oil
Trehalose
Hydrolyzed Algin
Micrococcus Lysate
Maris Sal
Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate
Lactoperoxidase
Glucose Oxidase
Urea
Glucose
Polyacrylamide
Glyceryl Polymethacrylate
PEG-8
Laureth-7
Lecithin
Triacetin
Sodium Chloride
Polyquaternium-51
Potassium Phosphate
Alcohol Denat.
Parfum
Limonene
Linalool
Hydroxycitronellal
Citronellol
Geraniol
BHT
Disodium EDTA
Sorbic Acid
Chlorphenesin
Potassium Sorbate
Phenoxyethanol
Algae Extract, Cyclopentasiloxane, Petrolatum, Glyceryl Distearate, Phenyl Trimethicone, Cyclohexasiloxane, Butylene Glycol, Cholesterol, Butyrospermum Parkii Butter, Steareth-10, Dimethicone, Glyceryl Stearate Se, Polysilicone-11, Glyceryl Triacetyl Ricinoleate, Macadamia Integrifolia Seed Oil, Glycerin, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Water, Citrus Aurantifolia Peel Extract, Laminaria Digitata Extract, Crithmum Maritimum Extract, Salicornia Herbacea Extract, Plankton Extract, Chlorella Vulgaris Extract, Rosmarinus Officinalis Leaf Extract, Sodium Hyaluronate, Tocopheryl Acetate, Acetyl Hexapeptide-8, Caffeine, Tetrahexyldecyl Ascorbate, Palmitoyl Hexapeptide-12, Caprylic/Capric Triglyceride, Triethylhexanoin, Sodium PCA, Cetyl Alcohol, Diethylhexyl Succinate, Isocetyl Stearoyl Stearate, Cyanocobalamin, C13-14 Isoparaffin, Distearyldimonium Chloride, Dipalmitoyl Hydroxyproline, Sucrose, Hydrogenated Vegetable Oil, Trehalose, Hydrolyzed Algin, Micrococcus Lysate, Maris Sal, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Lactoperoxidase, Glucose Oxidase, Urea, Glucose, Polyacrylamide, Glyceryl Polymethacrylate, PEG-8, Laureth-7, Lecithin, Triacetin, Sodium Chloride, Polyquaternium-51, Potassium Phosphate, Alcohol Denat., Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Geraniol, BHT, Disodium EDTA, Sorbic Acid, Chlorphenesin, Potassium Sorbate, Phenoxyethanol
Amniotic Fluid
Lanolin Oil
Propylene Glycol
Pentylene Glycol
Sodium Acrylates Copolymer
Ethylhexyl Palmitate
Squalane
Raspberry Seed Oil/Palm Oil Aminopropanediol Esters
Hydrolyzed Placental Protein
Hydrolyzed Gelatin
Yeast Extract
Hydrolyzed Ceratonia Siliqua Seed Extract
Sodium Lauroyl Lactylate
Sodium Dehydroacetate
Luffa Cylindrica Seed Oil
Tocopherol
Dimethylmethoxy Chromanol
Embryo Extract
Helianthus Annuus Seed Oil
Ethylhexylglycerin
Ceramide NP
Potassium Sulfate
Ceramide AP
Phytosphingosine
Papain
Xanthan Gum
Carbomer
Caprylyl Glycol
Diaminopropionoyl Tripeptide-33
Ceramide EOP
Water, Amniotic Fluid, Lecithin, Lanolin Oil, Propylene Glycol, Pentylene Glycol, Sodium Acrylates Copolymer, Glycerin, Alcohol Denat., Ethylhexyl Palmitate, Squalane, Raspberry Seed Oil/Palm Oil Aminopropanediol Esters, Hydrolyzed Placental Protein, Hydrolyzed Gelatin, Yeast Extract, Hydrolyzed Ceratonia Siliqua Seed Extract, Phenoxyethanol, Sodium Lauroyl Lactylate, Sodium Dehydroacetate, Luffa Cylindrica Seed Oil, Tocopherol, Dimethylmethoxy Chromanol, Embryo Extract, Helianthus Annuus Seed Oil, Ethylhexylglycerin, Ceramide NP, Cholesterol, Potassium Sulfate, Ceramide AP, Phytosphingosine, Papain, Xanthan Gum, Carbomer, Caprylyl Glycol, Diaminopropionoyl Tripeptide-33, Ceramide EOP
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Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Alcohol Denat. is an alcohol with a denaturant property. It is created by mixing ethanol with other additives.
The "denat" part just means "denatured"; common denaturants include Denatonium Benzoate, t-butyl alcohol, and Diethyl Phthalate. This step makes the alcohol undrinkable (and lets brand skip taxes related to beverage alcohol).
This ingredient gets a bad rep because it is irritating and drying due to its astringent property. Astringents draw out natural oils in tissue to constrict pores and dry out your skin.
However, alcohol denat. is not all that bad.
Due to its low molecular weight, alcohol denat. tends to evaporate quickly. One study on pig skin found half of applied alcohol evaporated in 10 seconds and less than 3% stayed on skin.
This also helps other ingredients become better absorbed upon application.
Studies are conflicted about whether this ingredient causes skin dehydration. One study from 2005 found adding emollients to propanol-based sanitizer decreased skin dryness and irritation. Another study found irritation only occurs if your skin is already damaged.
Small amounts of alcohol are generally tolerated by oily skin or people who live in humid environments.
The rule of thumb is this ingredient will probably not affect your skin much if it is near the end of an ingredients list.
One thing to note: People with ALDH2 (aldehyde dehydrogenase 2) deficiency may experience skin irritation from continued alcohol use. About 8% of the world's population have this deficiency.
The Cosmetic Ingredient Review Expert Panel has determined denatured alcohols to be safe for use in concentrations between 0.05% and 12% (depending on which denaturant is used).
Also...
This ingredient has antimicrobial and solvent properties.
The antimicrobial property helps preserve products and increase their shelf life. As a solvent, it helps dissolve other ingredients.
Look for formulas that contain glycerin, hyaluronic acid, or panthenol if you want to offset any drying effect.
This ingredient will trip away your skin's natural oils/lipids that help it lock in moisture. This can worsen dryness, trigger eczema flare-ups, and aggravate rosacea.
Be sure to patch test any product with this ingredient if you have dry or sensitive skin, eczema, or rosacea.
Cholesterol is a lipid that is naturally found in human skin and is one of the three key components of your skin barrier. In skincare, it is an emollient and barrier-repairing ingredient.
It works by fitting directly into the lipid layers of skin to help restore structure and reduce transepidermal water loss (TEWL).
This is a great ingredient for dry, compromised, or aging skin; our skin starts to produce less cholesterol with age.
Research shows cholesterol works best in combination with ceramides and fatty acids, the other two major components in your skin barrier.
Cholesterol is also a well-establish penetration enhancer and can help other actives absorb more effectively.
Cosmetic-grade cholesterol is usually derived from lanolin but plant and synthetic options also exist. We recommend reaching out to the brand if you have questions about their source of cholesterol.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.
Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:
It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.
Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).
It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.
On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.
Another perk of this ingredient is that it stays functional across a wide pH range (3-10).
You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.
Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.
Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.
Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!