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Jorgobé Multi Peptide Lifting Filler Versus Drunk Elephant B-Hydra Intensive Hydration Serum

Jorgobé Multi Peptide Lifting Filler Versus Drunk Elephant B-Hydra Intensive Hydration Serum This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Acetyl Hexapeptide-8 to soften the look of wrinkles. This hydrating serum is formulated around S

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Jorgobé Multi Peptide Lifting Filler Versus Drunk Elephant B-Hydra Intensive Hydration Serum

This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Acetyl Hexapeptide-8 to soften the look of wrinkles.

This hydrating serum is formulated around Sclerocarya Birrea Seed Oil and Panthenol to hydrate skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Glycerin

Pentylene Glycol

Coco-Caprylate/Caprate

Butyrospermum Parkii Butter

Sclerotium Gum

Ethylhexyl Stearate

Sodium PCA

Squalane

Glyceryl Stearate Citrate

Disodium Acetyl Glucosamine Phosphate

Palmitoyl Tripeptide-38

Acetyl Hexapeptide-8

Sodium Hyaluronate Crosspolymer

Dipotassium Glycyrrhizate

Glyceryl Caprylate

Caprylyl Glycol

Hydrolyzed Jojoba Esters

Jojoba Esters

Ethylhexylglycerin

Hydroxypropyl Cyclodextrin

Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate

Sodium Isostearate

Sodium Gluconate

Water, Glycerin, Pentylene Glycol, Coco-Caprylate/Caprate, Butyrospermum Parkii Butter, Sclerotium Gum, Ethylhexyl Stearate, Sodium PCA, Squalane, Glyceryl Stearate Citrate, Disodium Acetyl Glucosamine Phosphate, Palmitoyl Tripeptide-38, Acetyl Hexapeptide-8, Sodium Hyaluronate Crosspolymer, Dipotassium Glycyrrhizate, Glyceryl Caprylate, Caprylyl Glycol, Hydrolyzed Jojoba Esters, Jojoba Esters, Ethylhexylglycerin, Hydroxypropyl Cyclodextrin, Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate, Sodium Isostearate, Sodium Gluconate

Coconut Alkanes

Ammonium Acryloyldimethyltaurate/Vp Copolymer

Sclerocarya Birrea Seed Oil

Wheat Amino Acids

Ananas Sativus Fruit Extract

Berberis Vulgaris Root Extract

Citrullus Lanatus Fruit Extract

Lens Esculenta Fruit Extract

Pyrus Malus Fruit Extract

Panthenol

Niacinamide

Cyclodextrin

Sodium Hyaluronate

Sodium Lactate

Phenoxyethanol

Hydroxyproline

Trisodium Ethylenediamine Disuccinate

Citric Acid

Chlorphenesin

Water, Coconut Alkanes, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Glycerin, Pentylene Glycol, Sclerocarya Birrea Seed Oil, Wheat Amino Acids, Ananas Sativus Fruit Extract, Berberis Vulgaris Root Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Coco-Caprylate/Caprate, Panthenol, Sodium PCA, Sodium Hyaluronate Crosspolymer, Dipotassium Glycyrrhizate, Niacinamide, Cyclodextrin, Sodium Hyaluronate, Sodium Lactate, Phenoxyethanol, Hydroxyproline, Trisodium Ethylenediamine Disuccinate, Citric Acid, Caprylyl Glycol, Chlorphenesin, Ethylhexylglycerin

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Coco-Caprylate/Caprate is a lightweight ester created from coconut oil fatty acids, caprylic acid, and capric acid.

It is an emollient that helps soften skin and reduce transepidermal water loss (TEWL). What sets it apart from heavier emollients is its ultralight, non-greasy feel.

Once applied, this ingredient dries down quickly and leaves a dry, silky finish behind. This also helps improve spreadability and texture.

This ingredient has an excellent safety-record and is non-irritating.

Typical concentrations for cosmetics range from 0.5-62%.

Research on Malassezia growth found no growth on fatty acid esters with chain lengths shorter than 12 carbons (it prefers C11-24).

Since Coco-Caprylate/Caprate is built on C8 and C10 fatty acids, it is out of the range that Malassezia metabolizes, and therefore safe for fungal acne.

Dipotassium Glycyrrhizate comes from licorice root.

Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties.

One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs.

Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties.

Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this.

Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation.

Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues.

Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that:

The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure.

Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula:

Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses.

On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations.

Typical use levels in a formula run about 1-5%.

Sodium Hyaluronate Crosspolymer is a crosslinked version of sodium hyaluronate. This just means it's linked into a 3D mesh network that lets it be more stable and sit on skin as a cohesive, gel-like film rather than sinking into skin.

A 2016 human skin study found crosslinked HA increased epidermal water content by 7.6% over the control group and reduced transepidermal water loss by 27.8%.

A follow-up clinical trial found that a topical crosslinked HA serum applied after fillers, microneedling, or chemical peels was well-tolerated and enhanced skin quality at 14 / 28 days.

More recent research suggests that concentrations as low as 0.03% can act as a penetration enhancer for other skincare actives.

Sodium PCA (the salt of PCA) is one of the most well-established humectants in skincare.

Why is it so special? Your skin already makes it naturally; it's a natural component of your skin's Natural Moisturizing Factor (NMF), or the mix of water-binding compounds inside your skin cells that keeps things soft and hydrated.

As a cosmetic ingredient, it grabs water and holds it in the upper layers of skin to smooth roughness and ease dehydration.

There's some clinical support for the NMF approach with a study showing that a cream built to mimic the skin's NMF significantly boosted hydration.

Safety-wise, this ingredient non-irritating, non-comedogenic, and non-phototoxic in testing, with minimal skin absorption.

It also works really well with other hydrators like glycerin or hyaluronic acid, and typical usage is somewhere between 0.2-4%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Source: realpeptides.co ↗
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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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