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Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Numbuzin No.3 Super Glowing Essence Toner

Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Numbuzin No.3 Super Glowing Essence Toner This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier. This brightening toner is formulated aroun

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Numbuzin No.3 Super Glowing Essence Toner

This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier.

This brightening toner is formulated around Niacinamide and Lactobacillus Ferment to brighten dull-looking skin and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Bifida Ferment Lysate

Methyl Gluceth-20

PEG-75

Bis-PEG-18 Methyl Ether Dimethyl Silane

Butylene Glycol

Propanediol

Cola Acuminata Seed Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Tripeptide-32

Ethylhexylglycerin

Sodium Rna

Bisabolol

Glycereth-26

Squalane

Sodium Hyaluronate

Oleth-3 Phosphate

Caprylyl Glycol

Lactobacillus Ferment

Oleth-3

Oleth-5

Anthemis Nobilis Flower Extract

Faex Extract

Choleth-24

Hydrogenated Lecithin

Ceteth-24

Tocopheryl Acetate

Ethylhexyl Methoxycinnamate

Hexylene Glycol

Carbomer

Triethanolamine

Trisodium EDTA

BHT

Xanthan Gum

Phenoxyethanol

CI 14700

CI 19140

Water, Bifida Ferment Lysate, Methyl Gluceth-20, PEG-75, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Propanediol, Cola Acuminata Seed Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Tripeptide-32, Ethylhexylglycerin, Sodium Rna, Bisabolol, Glycereth-26, Squalane, Sodium Hyaluronate, Oleth-3 Phosphate, Caprylyl Glycol, Lactobacillus Ferment, Oleth-3, Oleth-5, Anthemis Nobilis Flower Extract, Faex Extract, Choleth-24, Hydrogenated Lecithin, Ceteth-24, Tocopheryl Acetate, Ethylhexyl Methoxycinnamate, Hexylene Glycol, Carbomer, Triethanolamine, Trisodium EDTA, BHT, Xanthan Gum, Phenoxyethanol, CI 14700, CI 19140

Dipropylene Glycol

1,2-Hexanediol

Niacinamide

Glycerin

Spiraea Ulmaria Extract

Lactococcus/Bean Seed Extract Ferment Filtrate

Lactobacillus/Rice Ferment

Chlorella Ferment

Lactobacillus/Algae Extract Ferment

Saccharomyces/Grape Ferment Extract

Lactobacillus/Pumpkin Ferment Extract

Lactobacillus/Soybean Ferment Extract

Lactobacillus/Soybean Extract Ferment Filtrate

Saccharomyces/Rice Ferment Filtrate

Saccharomyces/Barley Seed Ferment Filtrate

Saccharomyces/Calcium Ferment

Saccharomyces/Laminaria Saccharina Ferment

Saccharomyces/Potato Extract Ferment Filtrate

Lactobacillus/Eriodictyon Californicum Ferment Extract

Lactobacillus/Water Hyacinth Ferment

Lactobacillus/Rye Flour Ferment

Lactobacillus/Hibiscus Sabdariffa Flower Ferment Filtrate

Lactobacillus/Milk Ferment Filtrate

Lactobacillus

Lactobacillus/Acerola Cherry Ferment

Lactobacillus Ferment Lysate Filtrate

Lactococcus/Milk Ferment Lysate

Lactococcus Ferment

Lactococcus Ferment Extract

Lactococcus Ferment Lysate

Streptococcus Thermophilus Ferment

Aureobasidium Pullulans Ferment Filtrate

Bifida Ferment Filtrate

Leuconostoc/Radish Root Ferment Filtrate

Lactobacillus/Wasabia Japonica Root Ferment Extract

Lactobacillus/Punica Granatum Fruit Ferment Extract

Bacillus/Glutamic Acid Ferment Filtrate

Bacillus/Rice Bran Extract/Soybean Extract Ferment Filtrate

Monascus/Rice Ferment

Saccharomyces/Rice Bran Ferment Filtrate Extract

Saccharomyces/Rice Bran Ferment

Lactobacillus/Pear Juice Ferment Filtrate

Pichia Ferment Lysate Filtrate

Alteromonas Ferment Extract

Saccharomyces/Coix Lacryma-Jobi Ma-Yuen Seed Ferment Filtrate

Saccharomyces/Soy Protein Ferment

Sphingomonas Ferment Extract

Saccharomyces/Malachite Ferment

Saccharomyces Ferment

Saccharomyces Ferment Filtrate

Aspergillus Ferment

Aspergillus/Glucose/Soybean/Starch Ferment Filtrate

Pelargonium Graveolens Flower Oil

Polyglyceryl-10 Laurate

Cetearyl Alcohol

Betaine

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

Tromethamine

Polyquaternium-51

Hydroxyethylcellulose

Adenosine

Geraniol

Citronellol

Water, Dipropylene Glycol, Glycereth-26, 1,2-Hexanediol, Niacinamide, Butylene Glycol, Glycerin, Methyl Gluceth-20, Spiraea Ulmaria Extract, Lactococcus/Bean Seed Extract Ferment Filtrate, Lactobacillus/Rice Ferment, Chlorella Ferment, Lactobacillus/Algae Extract Ferment, Saccharomyces/Grape Ferment Extract, Lactobacillus/Pumpkin Ferment Extract, Lactobacillus/Soybean Ferment Extract, Lactobacillus/Soybean Extract Ferment Filtrate, Saccharomyces/Rice Ferment Filtrate, Saccharomyces/Barley Seed Ferment Filtrate, Saccharomyces/Calcium Ferment, Saccharomyces/Laminaria Saccharina Ferment, Saccharomyces/Potato Extract Ferment Filtrate, Lactobacillus/Eriodictyon Californicum Ferment Extract, Lactobacillus/Water Hyacinth Ferment, Lactobacillus/Rye Flour Ferment, Lactobacillus/Hibiscus Sabdariffa Flower Ferment Filtrate, Lactobacillus/Milk Ferment Filtrate, Lactobacillus, Lactobacillus/Acerola Cherry Ferment, Lactobacillus Ferment, Lactobacillus Ferment Lysate Filtrate, Lactococcus/Milk Ferment Lysate, Lactococcus Ferment, Lactococcus Ferment Extract, Lactococcus Ferment Lysate, Streptococcus Thermophilus Ferment, Aureobasidium Pullulans Ferment Filtrate, Bifida Ferment Filtrate, Leuconostoc/Radish Root Ferment Filtrate, Lactobacillus/Wasabia Japonica Root Ferment Extract, Lactobacillus/Punica Granatum Fruit Ferment Extract, Bacillus/Glutamic Acid Ferment Filtrate, Bacillus/Rice Bran Extract/Soybean Extract Ferment Filtrate, Monascus/Rice Ferment, Saccharomyces/Rice Bran Ferment Filtrate Extract, Saccharomyces/Rice Bran Ferment, Lactobacillus/Pear Juice Ferment Filtrate, Pichia Ferment Lysate Filtrate, Alteromonas Ferment Extract, Saccharomyces/Coix Lacryma-Jobi Ma-Yuen Seed Ferment Filtrate, Saccharomyces/Soy Protein Ferment, Sphingomonas Ferment Extract, Saccharomyces/Malachite Ferment, Saccharomyces Ferment, Saccharomyces Ferment Filtrate, Aspergillus Ferment, Aspergillus/Glucose/Soybean/Starch Ferment Filtrate, Pelargonium Graveolens Flower Oil, Sodium Hyaluronate, Polyglyceryl-10 Laurate, Cetearyl Alcohol, Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Polyquaternium-51, Hydroxyethylcellulose, Adenosine, Geraniol, Citronellol

Reviews

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Glycereth-26 is a synthetic ingredient and polyethylene glycol ether of Glycerin. Glycerin is already naturally found in your skin and helps keep your skin moisturized.

It is a humectant and helps add texture to products. It can make your product thicker.

As a humectant, it helps draw moisture from the air to your skin. This helps your skin stay hydrated.

This ingredient is made when the Lactobacillus bacteria (the same kind that makes yogurt and kimchi) are allowed to ferment a nutrient medium.

As it ferments, it collects lactic acid, peptides, enzymes, and other bioactive metabolites to provide:

A 2023 review noted that probiotic fermentation ingredients like this one can enhance antioxidant capacity, reduce UV-induced oxidative damage, and support barrier function.

One clinical study from the same year showed a Lactobacillus ferment lysate significantly reduced transepidermal water loss and improved skin hydration.

Another review highlighted that topical Lactobacillus-based preparations can improve ceramide levels in the stratum corneum, support barrier integrity, and even help reduce S. aureus colonization in atopic dermatitis.

Why is this so cool?

Basically, your skin's outer layer works as a brick wall; skin cells are bricks and ceramides are the mortar holding it together. Moisture escapes, irritants get in, and your skin gets dry and reactive when ceramide levels drop. On top of that, "bad" skin bacteria S. aureus loves to move in when your barrier is weak to make inflammation and irritation worse.

So Lactobacillus ferment is basically patching the wall and evicting the troublemaker when it boosts ceramide production and help keep S. aureus in check.

On top of all this, it also acts as a mild antimicrobial preservative booster.

Just so you know, most studies focus on specific strains or the lysate form rather than this generic "Lactobacillus Ferment", so results can vary.

Though it's a promising ingredient, it doesn't have decades of robust clinical data behind it just yet.

Lactobacillus Ferment is generally considered safe for fungal-acne prone skin. The key thing to understand is that it comes from bacteria, not yeast or fungus.

Yeast-derived ferments (like galactomyces) have been shown to activate a protein that's linked to Malassezia-related skin issues whereas lactobacillus doesn't have that problem.

Its byproducts also don't contain the types of fatty acids (C11-24 chain lengths) that Malassezia feeds on.

Methyl Gluceth-20 is a humectant. Humectants help draw moisture from the air to your skin.

It is created by combining polyethylene glycol with glucose.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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