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Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Guerlain Abeille Royale Double R Renew & Repair Advanced Serum

Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Guerlain Abeille Royale Double R Renew & Repair Advanced Serum This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier. This smoothing serum

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Estée Lauder Advanced Night Repair Synchronized Recovery Complex II Versus Guerlain Abeille Royale Double R Renew & Repair Advanced Serum

This barrier-repair serum is formulated around Bifida Ferment Lysate to strengthen the skin barrier.

This smoothing serum is formulated around Gluconolactone and Royal Jelly to refine skin texture and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Bifida Ferment Lysate

Methyl Gluceth-20

PEG-75

Bis-PEG-18 Methyl Ether Dimethyl Silane

Butylene Glycol

Propanediol

Cola Acuminata Seed Extract

Hydrolyzed Algin

Pantethine

Caffeine

Lecithin

Tripeptide-32

Ethylhexylglycerin

Sodium Rna

Bisabolol

Glycereth-26

Squalane

Sodium Hyaluronate

Oleth-3 Phosphate

Caprylyl Glycol

Lactobacillus Ferment

Oleth-3

Oleth-5

Anthemis Nobilis Flower Extract

Faex Extract

Choleth-24

Hydrogenated Lecithin

Ceteth-24

Tocopheryl Acetate

Ethylhexyl Methoxycinnamate

Hexylene Glycol

Carbomer

Triethanolamine

Trisodium EDTA

BHT

Xanthan Gum

Phenoxyethanol

CI 14700

CI 19140

Water, Bifida Ferment Lysate, Methyl Gluceth-20, PEG-75, Bis-PEG-18 Methyl Ether Dimethyl Silane, Butylene Glycol, Propanediol, Cola Acuminata Seed Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Tripeptide-32, Ethylhexylglycerin, Sodium Rna, Bisabolol, Glycereth-26, Squalane, Sodium Hyaluronate, Oleth-3 Phosphate, Caprylyl Glycol, Lactobacillus Ferment, Oleth-3, Oleth-5, Anthemis Nobilis Flower Extract, Faex Extract, Choleth-24, Hydrogenated Lecithin, Ceteth-24, Tocopheryl Acetate, Ethylhexyl Methoxycinnamate, Hexylene Glycol, Carbomer, Triethanolamine, Trisodium EDTA, BHT, Xanthan Gum, Phenoxyethanol, CI 14700, CI 19140

Glycerin

Alcohol

Gluconolactone

Pentylene Glycol

Caprylic/Capric Triglyceride

Mel

Diglycerin

Mel Extract

Royal Jelly

Sodium Hydroxide

Polyacrylate Crosspolymer-6

Lauroyl Lysine

Coco-Caprylate/Caprate

Glyceryl Stearate

Limnanthes Alba Seed Oil

Avena Sativa Kernel Extract

Parfum

Glycolic Acid

Sorbitol

Chlorphenesin

Citric Acid

PPG-26-Buteth-26

Lactic Acid

Sodium Magnesium Silicate

Dimethicone

Sodium Stearoyl Glutamate

PEG-40 Hydrogenated Castor Oil

Algin

Sodium Benzoate

Sodium Citrate

Hydrolyzed Soy Flour

Malva Sylvestris Extract

Albizia Julibrissin Bark Extract

Trisodium Ethylenediamine Disuccinate

Hydroxyacetophenone

Adenosine

Rosmarinus Officinalis Leaf Extract

Polyvinyl Alcohol

Biosaccharide Gum-2

Caramel

Cellulose Gum

Potassium Sorbate

CI 77492

Lactobacillus Ferment Lysate

Yeast Ferment Extract

Silica

CI 77491

Water, Glycerin, Propanediol, Alcohol, Gluconolactone, Butylene Glycol, Pentylene Glycol, Caprylic/Capric Triglyceride, Squalane, Mel, Diglycerin, Mel Extract, Royal Jelly, Sodium Hydroxide, Polyacrylate Crosspolymer-6, Lauroyl Lysine, Coco-Caprylate/Caprate, Glyceryl Stearate, Limnanthes Alba Seed Oil, Avena Sativa Kernel Extract, Parfum, Glycolic Acid, Sorbitol, Chlorphenesin, Carbomer, Citric Acid, PPG-26-Buteth-26, Lactic Acid, Sodium Magnesium Silicate, Dimethicone, Xanthan Gum, Sodium Hyaluronate, Sodium Stearoyl Glutamate, PEG-40 Hydrogenated Castor Oil, Algin, Sodium Benzoate, Sodium Citrate, Hydrolyzed Soy Flour, Malva Sylvestris Extract, Albizia Julibrissin Bark Extract, Trisodium Ethylenediamine Disuccinate, Hydroxyacetophenone, Adenosine, Rosmarinus Officinalis Leaf Extract, Polyvinyl Alcohol, Biosaccharide Gum-2, Caprylyl Glycol, Caramel, Cellulose Gum, Potassium Sorbate, CI 77492, Lactobacillus Ferment Lysate, Yeast Ferment Extract, Silica, CI 77491

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.

Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.

It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.

Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.

A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).

It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.

This is due to how structurally similar it is to what your skin already produces.

Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.

Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.

No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).

Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.

This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.

Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.

Read more about squalene with an "e".

Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.

The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.

Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.

A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.

The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

Xanthan gum is used as a stabilizer and thickener within cosmetic products. It helps give products a sticky, thick feeling - preventing them from being too runny.

On the technical side of things, xanthan gum is a polysaccharide - a combination consisting of multiple sugar molecules bonded together.

Xanthan gum is a pretty common and great ingredient. It is a natural, non-toxic, non-irritating ingredient that is also commonly used in food products.

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About the author

Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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