Educational guide
Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum Versus FARSALI Renewal Fluid Cream
Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum Versus FARSALI Renewal Fluid Cream This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wr
This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.
Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum Versus FARSALI Renewal Fluid Cream
This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles.
This anti-aging moisturizer is formulated around Tetrahexyldecyl Ascorbate and Niacinamide to soften the look of wrinkles and brighten dull-looking skin.
What's inside
Key Ingredients
Benefits
Concerns
Ingredients Side-by-side
Water
Bifida Ferment Lysate
PEG-8
Propanediol
Bis-PEG-18 Methyl Ether Dimethyl Silane
Methyl Gluceth-20
Glycereth-26
PEG-75
Butylene Glycol
Adansonia Digitata Seed Extract
Tripeptide-32
Sodium Hyaluronate
Faex Extract
Lactobacillus Ferment
Cola Acuminata Seed Extract
Anthemis Nobilis Flower Extract
Hydrolyzed Algin
Pantethine
Caffeine
Lecithin
Sodium Rna
Bisabolol
Squalane
Glycerin
Oleth-3 Phosphate
Caprylyl Glycol
Oleth-3
Oleth-5
Choleth-24
Hydrogenated Lecithin
Jojoba Wax PEG-120 Esters
Ceteth-24
Tocopheryl Acetate
Carbomer
Triethanolamine
Tetrasodium EDTA
BHT
Xanthan Gum
Potassium Sorbate
Disodium EDTA
Phenoxyethanol
CI 14700
CI 19140
Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140
Caprylic/Capric Triglyceride
Tetrahexyldecyl Ascorbate
Niacinamide
Diheptyl Succinate
Lactic Acid
Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Rosa Canina Fruit Oil
Cetyl Stearate
Isostearyl Isostearate
Potassium Cetyl Phosphate
Allantoin
Acetyl Hexapeptide-8
Acetyl Octapeptide-3
Acetyl Tetrapeptide-2
Copper Tripeptide-1
Nonapeptide-1
Palmitoyl Tetrapeptide-7
Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-38
Pentapeptide-18
Ceramide As
Ceramide AP
Ceramide Ns
Cholesterol
Pentapeptide-28
Polyacrylate Crosspolymer-6
Ceramide NP
Ceramide EOP
Capryloyl Glycerin/Sebacic Acid Copolymer
Sorbitan Isostearate
Sodium Phytate
Centella Asiatica Extract
Aloe Barbadensis Leaf Juice
Sodium Benzoate
Sodium Hydroxide
Cetyl Alcohol
Stearic Acid
1,2-Hexanediol
Beta-Glucan
Euterpe Oleracea Fruit Extract
Porphyridium Cruentum Extract
Panax Ginseng Root Extract
Carica Papaya Fruit Extract
Lupinus Albus Seed Extract
Curcuma Longa Root Extract
Astragalus Membranaceus Root Extract
Camellia Sinensis Leaf Extract
Dipropylene Glycol
Glyceryl Stearate
Sucrose Distearate
Water, Propanediol, Caprylic/Capric Triglyceride, Glycerin, Tetrahexyldecyl Ascorbate, Niacinamide, Squalane, Diheptyl Succinate, Lactic Acid, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Rosa Canina Fruit Oil, Cetyl Stearate, Isostearyl Isostearate, Potassium Cetyl Phosphate, Allantoin, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Acetyl Tetrapeptide-2, Copper Tripeptide-1, Nonapeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Pentapeptide-18, Ceramide As, Ceramide AP, Ceramide Ns, Cholesterol, Pentapeptide-28, Polyacrylate Crosspolymer-6, Ceramide NP, Ceramide EOP, Capryloyl Glycerin/Sebacic Acid Copolymer, Tocopheryl Acetate, Sorbitan Isostearate, Sodium Phytate, Centella Asiatica Extract, Butylene Glycol, Aloe Barbadensis Leaf Juice, Sodium Benzoate, Sodium Hydroxide, Potassium Sorbate, Carbomer, Cetyl Alcohol, Stearic Acid, 1,2-Hexanediol, Beta-Glucan, Caprylyl Glycol, Euterpe Oleracea Fruit Extract, Porphyridium Cruentum Extract, Panax Ginseng Root Extract, Carica Papaya Fruit Extract, Lupinus Albus Seed Extract, Curcuma Longa Root Extract, Hydrogenated Lecithin, Astragalus Membranaceus Root Extract, Camellia Sinensis Leaf Extract, Dipropylene Glycol, Glyceryl Stearate, Sucrose Distearate
Reviews
Alternatives
Ingredients Explained
These ingredients are found in both products.
Ingredients higher up in an ingredient list are typically present in a larger amount.
Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:
Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.
Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.
Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.
Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.
Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).
Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture.
Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%.
It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier.
Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%.
A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions.
Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.
Topically, glycerin does several things at once:
Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.
Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.
This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.
Just know very high concentrations (>40%) can feel tacky in low humidity.
Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.
Hydrogenated Lecithin is a more stable version of lecithin.
It's made by taking lecithin (a phospholipid commonly found in soybeans and egg yolks) and hydrogenating it. This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily.
This ingredient is an emollient, emulsifier, and penetration enhancer. As an emollient, it helps soften and hydrate skin by trapping moisture within. As an emulsifier, it prevents oil and water ingredients from separating.
Hydrogenated Lecithin can form tiny spherical structures made of phospholipid bilayers called liposomes. These liposomes are able to capture compounds inside their structure and deliver them through the skin barrier.
Because phospholipids are a natural component of our cell membranes, this ingredient is inherently compatible with skin.
A 2021 study found lecithin-based surfactants were less harsh and more tolerable comared to Sodium Lauryl Sulfate (SLS).
Potassium Sorbate is a preservative used to prevent yeast and mold in products. It is commonly found in both cosmetic and food products.
This ingredient comes from potassium salt derived from sorbic acid. Sorbic acid is a natural antibiotic and effective against fungus.
Both potassium sorbate and sorbic acid can be found in baked goods, cheeses, dried meats, dried fruit, ice cream, pickles, wine, yogurt, and more.
You'll often find this ingredient used with other preservatives.
Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.
It’s often used to:
Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.
Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.
In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.
Interestingly, the size of the molecule affects its behavior:
Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.
Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.
You'll typically see concentrations between 0.1-2% for this ingredient.
Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum).
It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores.
This is due to how structurally similar it is to what your skin already produces.
Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer.
Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts.
No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 100% concentration).
Overall, it's a fantastic ingredient for hydration and is suitable for all skin types.
This depends on the source. Squalane can be derived from both plants and animals. Most squalane used in skincare comes from plants.
Please note: the source of squalane is only known if disclosed by the brand. We recommend reaching out to the brand if you have any questions about their squalane.
Read more about squalene with an "e".
Though squalane is often called an oil, it’s technically not one. It is a hydrocarbon, meaning it is only made of carbon and hydrogen. True oils are triglycerides and made of fatty acids and glycerol.
The term “oil-free” isn’t regulated so companies can define it however they want. Some exclude all oils, while others just avoid mineral oil or comedogenic oils.
Squalane has a comedogenic rating of 1 from the original 1972 study that tested raw ingredients under occlusion on rabbit ears. This system is not standardized or peer-reviewed, and using the raw ingredients is very different from how diluted cosmetic formulations are used on human skin.
A comedogenic rating of 1 means it is "unlikely to clog pores" according to the original rating system.
The overall formula of a product matters more than the individual ingredients on whether or not it will cause clogged pores.
Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.
Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.
It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.
One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.
Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.
Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.
This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.
Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.
The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.
Most leave-on skincare keeps it at the lower end, often between 0.5-1%.
Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.
So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.
You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!