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Shiseido Ultimune Power Infusing Eye Concentrate Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

Shiseido Ultimune Power Infusing Eye Concentrate Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex This barrier-repair eye moisturizer is formulated around Ectoin to strengthen the skin barrier and soften the look o

Written by Peptide Therapy Guide Editorial Team
For education only

This guide cannot diagnose a condition or recommend a personal treatment plan. Discuss medical questions with a qualified professional.

Shiseido Ultimune Power Infusing Eye Concentrate Versus Estée Lauder Advanced Night Repair Eye Concentrate Matrix Synchronized Recovery Complex

This barrier-repair eye moisturizer is formulated around Ectoin to strengthen the skin barrier and soften the look of wrinkles.

This barrier-repair eye moisturizer is formulated around Bifida Ferment Lysate and Caffeine to strengthen the skin barrier and soften the look of wrinkles.

What's inside

Key Ingredients

Benefits

Concerns

Ingredients Side-by-side

Water

Dimethicone

Glycerin

Dipropylene Glycol

Sd Alcohol 40-B

Sorbitol

PEG-10 Dimethicone

Dimethicone/Vinyl Dimethicone Crosspolymer

Calcium Stearate

Xylitol

Methyl Gluceth-10

Sodium Chloride

PEG/PPG-19/19 Dimethicone

Hydrogenated Polyisobutene

Phenoxyethanol

Cetyl Ethylhexanoate

Erythritol

Butylene Glycol

Cellulose Gum

PEG/PPG-14/7 Dimethyl Ether

Tocopheryl Acetate

Rosa Damascena Flower Water

Alcohol

Parfum

Tocopherol

Disodium EDTA

Ectoin

Phytosteryl/Octyldodecyl Lauroyl Glutamate

PPG-3 Dipivalate

Linalool

Sodium Metabisulfite

Geraniol

Sodium Carboxymethyl Beta-Glucan

Ginkgo Biloba Leaf Extract

Citronellol

Ziziphus Jujuba Fruit Extract

Origanum Majorana Leaf Extract

Nelumbo Nucifera Germ Extract

Hydroxyproline

Houttuynia Cordata Extract

Lactobacillus/Hibiscus Sabdariffa Flower Ferment Filtrate

Sanguisorba Officinalis Root Extract

Thymus Serpyllum Extract

Perilla Ocymoides Leaf Extract

Iris Florentina Root Extract

Ganoderma Lucidum Stem Extract

Water, Dimethicone, Glycerin, Dipropylene Glycol, Sd Alcohol 40-B, Sorbitol, PEG-10 Dimethicone, Dimethicone/Vinyl Dimethicone Crosspolymer, Calcium Stearate, Xylitol, Methyl Gluceth-10, Sodium Chloride, PEG/PPG-19/19 Dimethicone, Hydrogenated Polyisobutene, Phenoxyethanol, Cetyl Ethylhexanoate, Erythritol, Butylene Glycol, Cellulose Gum, PEG/PPG-14/7 Dimethyl Ether, Tocopheryl Acetate, Rosa Damascena Flower Water, Alcohol, Parfum, Tocopherol, Disodium EDTA, Ectoin, Phytosteryl/Octyldodecyl Lauroyl Glutamate, PPG-3 Dipivalate, Linalool, Sodium Metabisulfite, Geraniol, Sodium Carboxymethyl Beta-Glucan, Ginkgo Biloba Leaf Extract, Citronellol, Ziziphus Jujuba Fruit Extract, Origanum Majorana Leaf Extract, Nelumbo Nucifera Germ Extract, Hydroxyproline, Houttuynia Cordata Extract, Lactobacillus/Hibiscus Sabdariffa Flower Ferment Filtrate, Sanguisorba Officinalis Root Extract, Thymus Serpyllum Extract, Perilla Ocymoides Leaf Extract, Iris Florentina Root Extract, Ganoderma Lucidum Stem Extract

Bifida Ferment Lysate

Isohexadecane

Bis-PEG-18 Methyl Ether Dimethyl Silane

Disteardimonium Hectorite

Isopropyl Isostearate

PPG-15 Stearyl Ether

Sucrose

Trehalose

Adansonia Digitata Seed Extract

Tripeptide-32

Faex Extract

Sodium Hyaluronate

Lactobacillus Ferment

Algae Extract

Sodium Rna

Hydrolyzed Algin

Caffeine

Hydroxyethyl Urea

Aminopropyl Ascorbyl Phosphate

Cucumis Sativus Fruit Extract

Anthemis Nobilis Flower Extract

Hordeum Vulgare Extract

Silybum Marianum Extract

Glycine Soja Seed Extract

Camelina Sativa Seed Oil

Betula Alba Bark Extract

Scutellaria Baicalensis Root Extract

Morus Bombycis Root Extract

Poria Cocos Sclerotium Extract

Propylene Glycol Dicaprate

Sodium Polyaspartate

Hydrogenated Lecithin

Phytosphingosine

Ethylhexylglycerin

Polysilicone-11

Isododecane

Helianthus Annuus Seed Extract

Polyethylene

Propylene Carbonate

Polyacrylate Crosspolymer-6

Lecithin

Glucose

Fructose

T-Butyl Alcohol

BHT

Hydroxyacetophenone

Sodium Dehydroacetate

Potassium Sorbate

CI 77491

Water, Dimethicone, Bifida Ferment Lysate, Isohexadecane, Glycerin, Butylene Glycol, Bis-PEG-18 Methyl Ether Dimethyl Silane, PEG-10 Dimethicone, Disteardimonium Hectorite, Isopropyl Isostearate, PPG-15 Stearyl Ether, Sucrose, Trehalose, Adansonia Digitata Seed Extract, Tripeptide-32, Faex Extract, Sodium Hyaluronate, Lactobacillus Ferment, Algae Extract, Sodium Rna, Hydrolyzed Algin, Caffeine, Hydroxyethyl Urea, Aminopropyl Ascorbyl Phosphate, Cucumis Sativus Fruit Extract, Anthemis Nobilis Flower Extract, Hordeum Vulgare Extract, Silybum Marianum Extract, Glycine Soja Seed Extract, Camelina Sativa Seed Oil, Sorbitol, Betula Alba Bark Extract, Scutellaria Baicalensis Root Extract, Morus Bombycis Root Extract, Poria Cocos Sclerotium Extract, Tocopheryl Acetate, Propylene Glycol Dicaprate, Sodium Polyaspartate, Hydrogenated Lecithin, Phytosphingosine, Ethylhexylglycerin, Polysilicone-11, Isododecane, Helianthus Annuus Seed Extract, Polyethylene, Propylene Carbonate, Polyacrylate Crosspolymer-6, Lecithin, Glucose, Fructose, T-Butyl Alcohol, Disodium EDTA, BHT, Hydroxyacetophenone, Sodium Dehydroacetate, Potassium Sorbate, Phenoxyethanol, CI 77491

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Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane.

What it does:

Dimethicone comes in different viscosities:

Depending on the viscosity, dimethicone has different properties.

Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity.

This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient.

Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy.

Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air.

This ingredient mainly works behind the scenes and helps with:

On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it.

One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin).

Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption.

You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%.

Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum.

Topically, glycerin does several things at once:

Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3.

Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin.

This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products.

Just know very high concentrations (>40%) can feel tacky in low humidity.

Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine.

Peg-10 Dimethicone is silicone with conditioner and emulsifier properties. It mostly acts as an emollient in skincare and and humectant in haircare.

According to the manufacturer, acidic formulations decrease the stability of this ingredient. It works best in neutral or near neutral formulations.

Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!).

It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome.

On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive.

Another perk of this ingredient is that it stays functional across a wide pH range (3-10).

You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own.

Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU.

Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages.

Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon.

Sorbitol is a sugar alcohol. It is a hydrating and moisturizing agent created from the reduction process of glucose.

Most sorbitol is usually made from potato starch. It is also found in fruits such as apples and pears.

As a humectant, Sorbitol helps draw water to the skin. This helps keep the skin hydrated. Sorbitol also helps create a thicker texture in products. You might find sorbitol in your toothpaste and other gels.

It is a non-irritating ingredient that is great for those with dry skin.

Sorbitol is a prebiotic. It helps promote the growth of healthy bacteria on your skin. The bacteria on your skin form a microbiome. This microbiome helps protect your skin from infection and harmful bacteria.

Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E.

Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life.

It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time.

One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found the skin gained protection against UV damage even though the conversion was slow and small.

Once converted, vitamin E acts as a skin's main fat-soluble antioxidant that fights free radicals to protect skin from damage.

Topical vitamin E generally boosts the skin's photoprotection, and it reduced UV-damage in animal models.

This ingredient has some brightening potential but it's more of a prevention ingredient than spot-fader. Cell studies show it can slow down melanin production but it's worth noting that it's not the most powerful brightener out there.

Overall, it has a pretty solid safety profile and has been found to be non-irritating and non-comedogenic. Allergic reactions may happen but stay rare due to how widely the ingredient gets used.

The concentration will vary depending on the formula; industry data shows 0.1% in baby lotions, 3% in lipsticks, and 5% in foot powders. You can also find this ingredient at 100% in a pure vitamin E oil.

Most leave-on skincare keeps it at the lower end, often between 0.5-1%.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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Peptide Therapy Guide Editorial Team

Editorial team for Peptide Therapy Guide.

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