Dr. Diamond's Metacine Instafacial Plasma Versus Biologique Recherche ISO-Placenta Regenerating Serum for Face

Dr. Diamond's Metacine Instafacial Plasma Versus Biologique Recherche ISO-Placenta Regenerating Serum for Face

This anti-aging serum is formulated around Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 and Sh-Oligopeptide-1 to soften the look of wrinkles and strengthen the skin barrier.

What's inside

Key Ingredients

Benefits

Ingredients Side-by-side

Water

Glycerin

1,2-Hexanediol

Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1

N-Prolyl Palmitoyl Tripeptide-56 Acetate

Sh-Oligopeptide-1

Sh-Oligopeptide-2

Sh-Polypeptide-1

Sh-Polypeptide-11

Sh-Polypeptide-9

Acetyl Hexapeptide-8

Acetyl Glutamine

Copper Tripeptide-1

Raphanus Sativus Root Extract

Bacillus/Folic Acid Ferment Filtrate Extract

Hydroxyacetophenone

Disodium Acetyl Glucosamine Phosphate

Sodium Glucuronate

Sodium Hyaluronate

Sodium Phytate

Magnesium Sulfate

Hydroxyethylcellulose

Lecithin

Citric Acid

Maltodextrin

Propanediol

Butylene Glycol

Pentylene Glycol

Ethylhexylglycerin

Caprylyl Glycol

Phenoxyethanol

Water, Glycerin, 1,2-Hexanediol, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, N-Prolyl Palmitoyl Tripeptide-56 Acetate, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-8, Acetyl Glutamine, Copper Tripeptide-1, Raphanus Sativus Root Extract, Bacillus/Folic Acid Ferment Filtrate Extract, Hydroxyacetophenone, Disodium Acetyl Glucosamine Phosphate, Sodium Glucuronate, Sodium Hyaluronate, Sodium Phytate, Magnesium Sulfate, Hydroxyethylcellulose, Lecithin, Citric Acid, Maltodextrin, Propanediol, Butylene Glycol, Pentylene Glycol, Ethylhexylglycerin, Caprylyl Glycol, Phenoxyethanol

Methylpropanediol

Ceratonia Siliqua Seed Extract

Camellia Sinensis Leaf Extract

Cryptomeria Japonica Bud Extract

Bacillus/Soybean Ferment Extract

Hexapeptide-11

Oligopeptide-1

Oligopeptide-2

Oligopeptide-3

Folic Acid

Triethanolamine

Sodium Benzoate

Water, Propanediol, Methylpropanediol, Butylene Glycol, Ceratonia Siliqua Seed Extract, Camellia Sinensis Leaf Extract, Cryptomeria Japonica Bud Extract, Bacillus/Soybean Ferment Extract, Hexapeptide-11, Oligopeptide-1, Oligopeptide-2, Oligopeptide-3, Acetyl Glutamine, Folic Acid, Sodium Hyaluronate, Citric Acid, Lecithin, 1,2-Hexanediol, Triethanolamine, Caprylyl Glycol, Sodium Benzoate

Alternatives

Ingredients Explained

These ingredients are found in both products.

Ingredients higher up in an ingredient list are typically present in a larger amount.

1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse.

It is a:

Humectant, drawing moisture into the skin

Emollient, helping to soften skin

Solvent, dispersing and stabilizing formulas

Preservative booster, enhancing the antimicrobial activity of other preservatives

We don't have a description for Acetyl Glutamine yet.

Butylene Glycol (or BG) is used within cosmetic products for a few different reasons:

Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients.

Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness.

Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created.

Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin.

Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on).

Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes.

Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath.

However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products.

Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH.

In skincare formulas, citric acid can:

While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants.

Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations.

Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger.

However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you are unsure.

Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids.

Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker:

It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers.

Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin.

It’s often used to:

Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent.

Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity.

In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface.

Interestingly, the size of the molecule affects its behavior:

Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair.

Many serums use a blend of both weights so you can get surface hydration plus longer-lasting and deeper effects.

You'll typically see concentrations between 0.1-2% for this ingredient.

Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product.

So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation.

You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!

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